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European Commission Approves Erdafitinib for Advanced Urothelial Carcinoma

Janssen-Cilag International NV, a Johnson & Johnson company, today announced that the European Commission (EC) has approved BALVERSA®▼(erdafitinib) as a once-daily oral monotherapy for the treatment of adult patients with unresectable or metastatic urothelial carcinoma (mUC), harbouring susceptible fibroblast growth factor receptor 3 (FGFR3) genetic alterations who have previously received at least one line of therapy containing a programmed death receptor-1 (PD-1) or programmed death-ligand 1 (PD-L1) inhibitor in the unresectable or metastatic treatment setting.

30 Aug 2024

Researchers on the Brink of a Scientific Breakthrough in Cancer Treatment

By figuring out how the body’s immune system targets diseased cells, a multinational team of scientists is on the cusp of a breakthrough in the fight against cancer.

29 Aug 2024

Gut Microbiome Influences Cancer Risk Through Carcinogen Metabolism

At any given time, over 10 trillion microbes call our guts their home. From breaking down nutrients in our food to strengthening our immunity against pathogens, these microbes play an essential role in how we interact with the world.

1 Aug 2024

Advancing Cancer Drug Discovery: The Enduring Value of Phenotypic Screening

The niche areas in which phenotypic screening continues to be advantageous over the targeted approach, and the recent advances in phenotypic screening technology that have increased their efficiency.

26 Jul 2024

Study Identifies Microproteins as Key Source of Tumor-Specific Antigens in Liver Cancer

If microproteins translated from noncanonical open reading frames (ncORFS) in long noncoding ribonucleic acids (RNAs) could be a potential source of tumor-specific antigens.

23 Jul 2024

Wild Chimpanzees Found to Consume Medicinal Plants to Combat Illness

Researchers from Africa and Europe observed habituated chimpanzee communities to understand this potentially self-medicating behavior.

26 Jun 2024

Lung Organoids Shed Light on Pseudomonas aeruginosa's Invasive Tactics

How do pathogens invade the lungs? Using human lung microtissues, a team at the Biozentrum of the University of Basel has uncovered the strategy used by a dangerous pathogen.

11 Jun 2024

New Insights into E. coli's UTI Survival Strategy

Due to anatomical peculiarities, women are particularly vulnerable to UTIs; nearly 50% of them will experience one at some point in their lives.

6 May 2024

Mutation in E. coli's Cellulose Machinery Unveiled as Cause of Severe Infections

Queensland researchers have discovered that a mutation allows some E. coli bacteria to cause severe disease in people while other bacteria are harmless, a finding that could help to combat antibiotic resistance.

22 Feb 2024

Bio-Techne’s Advanced Cell Diagnostics (ACD) Sets New Standard in Spatial Biology with Protease-Free RNAscope Multiomics

Bio-Techne Corporation today announced that Advanced Cell Diagnostics (ACD), a Bio-Techne spatial biology brand, has set a new standard with the development of a next-generation, protease-free RNAscope spatial multiomics workflow.

From Bio-Techne 30 Jan 2024

Researchers Develop Bio-Inspired Drug to Boost Efficacy of Cancer Immunotherapy

A new, bio-inspired drug restores the effectiveness of immune cells in fighting cancer, a team led by researchers at The University of Texas at Austin has found.

10 Oct 2023

Scientists Explain How Enhancer Reprogramming Promotes Tumor Cell Growth

Cancer cells can boost tumor development by hijacking enhancer DNA, which is typically utilized when tissues and organs form, according to researchers at the University of Toronto (U of T).

29 Sep 2023

Study Shows How Sensory Neurons Control Gastrointestinal Tracts

Gastrointestinal and digestive issues impact roughly 3 million people across the United States alone, and that number is growing.

4 Aug 2023

Study Reveals Key Insights Into the Evolution of Tumor Microenvironment in Gastric Cancer

A new study led by researchers at The University of Texas MD Anderson Cancer Center provides a deeper understanding of the evolution of the tumor microenvironment during gastric cancer progression.

7 Jul 2023

Loss of the Y Chromosome Impairs Body's Ability to Fight Cancer

According to recent Cedars-Sinai Cancer research, as men age, some of their cells lose the very feature that makes them biological males—the Y chromosome—and this loss impairs the body’s ability to fight cancer.

22 Jun 2023

Unraveling the Link Between Environmental Toxins and Lymphoma in Dogs

Lymphoma is a common cancer in dogs, but unlike human studies, which have associated the disease with environmental toxins, little is known about how it originates in dogs.

2 Jun 2023

Researchers Design Artificial Fibers that can Change Shape and Generate Force Like a Muscle

In two new studies, North Carolina State University researchers designed and tested a series of textile fibers that can change shape and generate force like a muscle.

26 May 2023

Study Offers New Insight into the Kinetics of Prostatic Inflammaging

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 9, entitled, "Highly multiplexed immune profiling throughout adulthood reveals kinetics of lymphocyte infiltration in the aging mouse prostate."

24 May 2023

New Genetic Mutations Linked to Canine Bladder Cancers Identified

Researchers have identified new genetic mutations linked to a subset of canine bladder cancers. Their findings have implications both for early cancer detection and for targeted treatments in dogs and humans.

26 Apr 2023

Previously unknown telomere and cancer connection to the immune system revealed

Johns Hopkins Medicine scientists say their 20-year study of more than 200 people with premature aging syndromes caused by abnormally short telomeres, or shortened repetitive DNA sequences at the ends of chromosomes, may upend long-held scientific dogma and settle conflicting studies about how and whether short telomeres contribute to cancer risk.

31 Mar 2023