Bone Health News and Research

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LINE-1 RNA from Ancient Viruses Promotes Bone Repair

Around half of the human genome is composed of DNA fragments originating from ancient viruses. These "transposable elements" (TEs) are now known to play various roles in modulating gene expression and disease development.

8 Aug 2024

Germ Cells Found to Drive Sex-Dependent Lifespan Differences in Vertebrates

Women live longer than men. This isn't unique to humans, either; we see this trend in a wide range of other animals. Biologists have theorized that the discrepancy in life expectancy between sexes might be partly related to reproduction, but how?

13 Jun 2024

Immune Checkpoint Inhibitors Confer a Protective Effect on Bone by Promoting Osteogenesis

Immune checkpoint inhibitors (ICIs), widely employed anticancer agents, have been found to impact bone turnover, potentially conferring a protective effect on bone through the promotion of osteogenesis.

3 Jun 2024

New Mechanism Regulating Tumor Growth in the Skeleton Identified

Tumor cells are known to be fickle sleeper agents, often lying dormant in distant tissues for years before reactivating and forming metastasis. Numerous factors have been studied to understand why the activation occurs, from cells and molecules to other components in the so-called tissue microenvironment.

11 Aug 2023

Identifying Drugs to Put the Brakes On Accelerated Aging From HIV Infection, Treatment

Antiretroviral cocktails can make human immunodeficiency virus, or HIV, undetectable and untransmittable, but both the virus and its treatment can also accelerate aging of bone and muscle.

24 May 2023

Effect of prune supplementation on the gut microbiome of postmenopausal women

New research published in the journal Food & Function indicates that daily prune consumption may improve the gut fecal microbiome of postmenopausal women. The fecal microbiome – the ecosystem of microorganisms found in one's fecal matter – reflects an individual's overall gut health. Results from the study showed notable enrichment in bacteria from the family Lachnospiraceae. This group of bacteria has been associated with an ability to decrease inflammatory markers in the body and help maintain the integrity of the gut barrier.

16 Feb 2023

Antibiotics deplete intestinal flora and weaken the immune response

According to a recent study conducted by scientists at Emory University in Atlanta, the administration of broad-spectrum antibiotics in mice with malignant melanoma, an aggressive type of skin cancer, expedited their metastatic bone growth.

12 Sep 2022

Study shows how the commensal oral microbiome can regulate alveolar bone health

It is becoming increasingly clear that the human microbiome – the collection of bacteria, viruses and fungi that live on and within us – significantly contributes to our health.

17 Feb 2022

Research reveals pathways controlling osteocyte development

Osteocytes are seen within bone tissue. They are cells with tree-like projections known as dendrites vital for receiving communication from other cells.

4 Nov 2021

Researchers map unique genetic profile of osteocytes for the first time

Researchers have mapped the specific genetic profile of the skeleton’s “master regulator” cells, called osteocytes, for the first time.

7 May 2021

Vegan diet leads to poorer bone health, shows study

The vegan diet is on-trend. How this type of diet affects health is the subject of scientific studies. In a new study from the German Federal Institute for Risk Assessment (BfR), the bone health of 36 vegans, as well as 36 people following a mixed-food diet, was determined with an ultrasound measurement of the heel bone.

5 Mar 2021

Adequate calcium, vitamin D intake should be ensured when adopting an increasingly plant-based diet

In a study conducted at the University of Helsinki, Finland, 136 adults adhered to one of three study diets for 12 weeks. One of them corresponded to the average Finnish diet, containing roughly 70% animal-derived protein of total protein, while most of the plant-based protein originated from cereal products.

11 Feb 2021

Longitudinal study identifies many genetic markers linked to bone mineral accrual

A multidisciplinary team of researchers led by Children's Hospital of Philadelphia has discovered several genetic markers associated with bone mineral accrual, which could ultimately help identify causes of eventual osteoporosis earlier in life through genetic testing.

7 Jan 2021

Plastics contain endocrine-disrupting chemicals that threaten human health, shows new report

Plastics contain and leach hazardous chemicals, including endocrine-disrupting chemicals (EDCs) that threaten human health.

16 Dec 2020

Dried plum diet prevents bone loss associated with spinal cord injury

Findings from a new study among mice show a diet high in dried plum (prunes) completely prevents bone loss associated with spinal cord injury (SCI), while also restoring some of the bone lost following SCI.

7 Oct 2020

Treatments targeting the gut microbiome can protect space travelers from adverse health problems

Space travelers who spend long periods of time in space can experience health problems, such as adverse effects on metabolism, and immunity.

9 Sep 2020

Psychoactive ingredient in marijuana may impair female fertility, study finds

Female eggs exposed to THC, the psychoactive ingredient in marijuana, have an impaired ability to produce viable embryos, and are significantly less likely to result in a viable pregnancy, according to an animal study accepted for presentation at ENDO 2020, the Endocrine Society's annual meeting.

6 Apr 2020