Botox is a drug made from a toxin produced by the bacterium Clostridium botulinum. It's the same toxin that causes a life-threatening type of food poisoning called botulism. Doctors use it in small doses to treat health problems, including, temporary removal of facial wrinkles, severe underarm sweating, cervical dystonia - a neurological disorder that causes severe neck and shoulder muscle contractions, blepharospasm - uncontrollable blinking, strabismus - misaligned eyes. Botox injections work by weakening or paralyzing certain muscles or by blocking certain nerves. The effects last about three to four months. Side effects can include pain at the injection site, flu-like symptoms, headache and upset stomach. Injections in the face may also cause temporary drooping eyelids. You should not use Botox if you are pregnant or breast feeding.
A team of researchers from the University of California, Irvine, have revealed the first crystal structures of the receptor-binding domain of botulinum neurotoxin E (BoNT/E) in complex with its human neuronal receptors, synaptic vesicle glycoprotein 2A (SV2A).
Scientists have found that botulinum toxin—commonly known as Botox—can expose the inner workings of the brain, in addition to smoothing out wrinkles.
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