Chaperones News and Research

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Study Unravels the Mystery of Hsp70 Chaperones

Proteins control most of the body's functions, and their malfunction can have severe consequences, such as neurodegenerative diseases or cancer. Therefore, cells have mechanisms in place to control protein quality.

9 Oct 2024

Unraveling the Key to Suppressing Protein Misfolding in Neurodegenerative Diseases

Proteins known as oligomeric chaperones help suppress the formation of misshaped proteins that cause a variety of degenerative and neurodegenerative diseases, such as Alzheimer's, Huntington's, and Parkinson's.

13 Apr 2024

New Synthetic Enzymes can Control Signaling Protein Vital to Embryonic Development

A University of Texas at Dallas bioengineer has developed synthetic enzymes that can control the behavior of the signaling protein Vg1, which plays a key role in the development of muscle, bone and blood in vertebrate embryos.

10 Nov 2023

Targeting Cellular Respiration for the Treatment of Glioblastoma

A new research perspective was published in Oncotarget's Volume 14 on May 4, 2023, entitled, "Targeting cellular respiration as a therapeutic strategy in glioblastoma."

22 May 2023

Researchers Elucidate the Molecular Mechanism of Protein Degradation by Extracellular Chaperones

When exposed to stressful conditions, several proteins tend to misfold and form aggregates inside or outside cells.

12 May 2023

Revealing an Unanticipated Mechanism for Chaperone-Mediated Ribosome Repair

Researchers have discovered that if oxidative stress destroys protein factories known as ribosomes, repair crews may go in to assist in repairing the damage so that production may restart rapidly.

26 Apr 2023

New research identifies a destination for zinc chaperone protein's deliveries

Most people don't think much about zinc. But all living things need zinc for survival. This trace element helps many proteins fold into the right shapes to do their jobs.

18 May 2022

Experts identify proteins that regulate dual processes

According to recent research, the protein UBR7 acts as a histone chaperone and controls histone re-deposition at certain sites at the time of DNA replication.

22 Dec 2021

Mitochondrial inner membrane fusion protein acts as a molecular chaperone

Cells contain numerous functional “micro-organs” known as organelles. Mitochondria, the “power plant” of the cell, are the energy-producing organelles.

25 Oct 2021

Prions may help yeast cope with rapidly changing environmental conditions

Prions are proteins found in the brain and familiar for their role in causing disease.

23 Sep 2021

Chaperone protein imbalance initiates toxic accumulation of tau in the aging brain

Chaperone protein imbalance can play a significant role in initiating toxic accumulation of tau in the aging brain - an early step in the development of Alzheimer's disease and related neurodegenerative disorders known as tauopathies, a new preclinical study by University of South Florida Health (USF Health) neuroscientists suggests.

21 Apr 2021

Chaperones News and Research

Study Unravels the Mystery of Hsp70 Chaperones

Unraveling the Key to Suppressing Protein Misfolding in Neurodegenerative Diseases

New Synthetic Enzymes can Control Signaling Protein Vital to Embryonic Development

Targeting Cellular Respiration for the Treatment of Glioblastoma

Researchers Elucidate the Molecular Mechanism of Protein Degradation by Extracellular Chaperones

Revealing an Unanticipated Mechanism for Chaperone-Mediated Ribosome Repair

New research identifies a destination for zinc chaperone protein's deliveries

Experts identify proteins that regulate dual processes

Mitochondrial inner membrane fusion protein acts as a molecular chaperone

Prions may help yeast cope with rapidly changing environmental conditions

Chaperone protein imbalance initiates toxic accumulation of tau in the aging brain

DNAJC9 protein plays a key role in protecting histones in the cell nucleus

Simple 'designer' pore reproduces selective cellular transport mechanisms

Study reveals the structure of heat shock proteins that could treat Huntington's disease

A Gene Mutation That Protects Against Disease

Researchers identify rare genetic marker that protects against cardiovascular disease

Study shows how chaperone activity influences the course of neurodegenerative diseases

Study reveals the role of Rubisco enzymes in carbon-fixing machinery of cyanobacteria

Study can help develop targeted drugs for cancer and other diseases

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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