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Predicting Disease-Causing Protein Interactions with PIONEER

Researchers at Cornell University and Cleveland Clinic developed an open-access computational platform and online database that helps identify targetable interactions between proteins for therapeutic purposes.

25 Oct 2024

Human Antibodies Offer Hope for Improved Black Widow Antivenom

Sera produced from horses can be used to treat serious illnesses caused by black widow bites. But this approach is not totally secure. To address this, scientists have produced entirely human antibodies that are capable of neutralizing the European black widow's alpha-latrotoxin.

13 Jun 2024

What Makes Certain Mushrooms 'Magic'?

In a recent study published in the journal Nature Communications, an international research team from various Universities including Hans Knöll Institute investigated the biosynthesis of psilocybin, the primary component of hallucinogenic mushrooms.

17 Apr 2024

TAM-Sense Offers Painless Imaging of Tumor Inflammation

The National Institutes of Health (NIH) has awarded two new grants totaling $6.7 million to researchers at the University of California San Diego School of Medicine.

2 Apr 2024

New Biomarker Offers Early Detection of ALS and FTD

Two progressively degenerative diseases, amyotrophic lateral sclerosis (ALS, commonly known as Lou Gehrig's disease) and frontotemporal dementia (FTD, recently in the news with the diagnoses of actor Bruce Willis and talk show host Wendy Williams), are linked by more than the fact that they both damage nerve cells critical to normal functioning -; the former affecting nerves in the brain and spinal cord leading to loss of movement, the latter eroding the brain regions controlling personality, behavior and language.

19 Mar 2024

RNA-Seq Unveils Molecular Subtypes for Tailored Pediatric B-ALL Treatment

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, representing more than 30% of all pediatric cases.

31 Jan 2024

Novel DNA Tension Probe Technology Offers Precise Measurement of Platelet Function

A novel technique to test platelet function within a person's blood sample is faster, easier and more precise than methods currently in use, an experimental study shows.

12 Dec 2023

INTEGRA Biosciences’ pipettes help to progress infectious disease testing

Cormeum Lab Services, a cutting-edge clinical testing laboratory in Louisiana, is using a range of pipetting solutions from INTEGRA Biosciences to streamline its infectious disease testing workflows.

From INTEGRA Biosciences 25 Oct 2023

AMP Releases CYP3A4 and CYP3A5 Genotyping Assay Recommendations

The Association for Molecular Pathology (AMP), the world’s leading professional society for molecular diagnostics, released consensus recommendations today to aid in the design and validation of clinical CYP3A4 and CYP3A5 genotyping assays, encourage standardization of testing across labs, and better patient care.

11 Jul 2023

First Humanized Mouse Model for Congenital Adrenal Hyperplasia Developed

Mice with a defected human gene responsible for a rare genetic disease, called congenital adrenal hyperplasia, have been developed for the first time.

16 May 2023

Women over 50 with genetic BRCA1 or BRCA2 mutation face a high risk of cancer

Although genetic mutations in BRCA1 or BRCA2 are associated with a younger onset of breast and ovarian cancer, women with these genetic mutations continue to face a high risk of cancer incidence after age 50, even if they have not been previously diagnosed with cancer.

27 Feb 2023

Employing molecular anchor for more effective CAR immunotherapies

Researchers at St. Jude Children’s Research Hospital discovered that immune cells with the attached protein boosted the killing of cancer, irrespective of the kind of cancer cell or the type of cancer being targeted.

3 Feb 2023

Diet plays a crucial role in liver disease outcome, mouse model shows

Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide. NAFLD patients are at higher risk of developing Non-alcoholic steatohepatitis (NASH), which causes severe and chronic liver inflammation, fibrosis and liver damage.

2 Jun 2021

New technological approach to rapidly develop new drugs without animal experiments

A team of researchers led by Professor Yaakov Nahmias, director of the Grass Center for Bioengineering at the Hebrew University of Jerusalem and founder of Tissue Dynamic, introduced a new technological approach that has the potential to rapidly develop new drugs without the need for animal experiments.

10 Mar 2021

Machine learning approach to identify drugs that could be repurposed to fight Covid-19

When the Covid-19 pandemic struck in early 2020, doctors and researchers rushed to find effective treatments.

16 Feb 2021

New protocol identifies mismatch repair deficiency

Researchers have developed a new integrated genetic/epigenetic DNA-sequencing protocol known as MultiMMR that can identify the presence and cause of mismatch repair (MMR) deficiency in a single test from a small sample of DNA in the colon, endometrial, and other cancers.

22 Jan 2021

Kobe University and Sysmex conduct joint research on new blood test for identifying COVID-19

Kobe University and Sysmex Corporation have been engaged in joint research on the ELISPOT method, a new blood test for identifying the novel coronavirus disease (COVID-19).

28 Dec 2020

Novel compounds may lead to potential treatment for rare terminal childhood illness

Researchers have discovered a method to “rescue” genetically mutated cells, providing opportunities to develop a new treatment for mitochondrial disease.

From University of Exeter 21 Dec 2020

CSIRO makes it easier for time-poor Australians to choose ready low carb meals

CSIRO, Australia’s national science agency, is partnering with Australian food manufacturers and retailers to make it easier for time-poor Australians to choose nutritious ready meals consistent with the successful CSIRO Low Carb Diet and Lifestyle Plan.

2 Nov 2020

New type of cancer immunotherapy trains the immune system to eliminate tumor cells

A groundbreaking new type of cancer immunotherapy developed at the Icahn School of Medicine at Mount Sinai trains the innate immune system to help it eliminate tumor cells through the use of nanobiologics, tiny materials bioengineered from natural molecules that are paired with a therapeutic component, according to a study published in Cell in October.