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Scientists Build Live African Swine Fever Virus From Synthetic DNA Using CRISPR

Utilizing CRISPR-Cas9, scientists reconstitute live African swine fever virus from synthetic genomes, accelerating vaccine development for this deadly virus.

2 Apr 2025

New Insights into How B Cells Strategically Clone High-Affinity Antibodies

A vaccine's ability to generate long-lasting, high-affinity antibodies hinges on a delicate balance. Upon exposure to a vaccine or pathogen, B cells scramble to refine their defenses, rapidly mutating in hopes of generating the most effective antibodies.

20 Mar 2025

Harbour BioMed and Insilico Collaborate on Advanced AI-Driven Antibody Discovery

Harbour BioMed (HKEX: 02142, the "Company"), a global biopharmaceutical company committed to the discovery, development and commercialization of novel antibody therapeutics focusing on immunology and oncology, and Insilico Medicine ("Insilico"), a clinical stage generative artificial intelligence (AI)-driven biotechnology company, today announced a strategic collaboration to accelerate the discovery and development of innovative therapeutic antibodies, leveraging their respective technological strengths in antibody discovery and artificial intelligence.

22 Feb 2025

Scientists Create First Healthy Mice with Two Fathers

A group of stem cell researchers has successfully engineered embryonic stem cells to create a bi-paternal mouse, a mouse with two male parents, that survived to adulthood.

29 Jan 2025

Discovery of Efficient Glycosyltransferases for Pterocarpan Glycoside Biosynthesis

A research team has identified two highly efficient glycosyltransferases, AmGT28 and AmGT44, from Astragalus membranaceus, which convert medicarpin to medicarpin 3-O-glucoside and show a preference for pterocarpans over isoflavonoids.

13 Aug 2024

Unveiling IRF1's Influence on Cancer Progression and Treatment Using Histology and Flow Cytometry

Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have discovered new information regarding the function of a protein known as interferon regulatory factor (IRF1) in the course of cancer and how it responds to treatment. This information may help increase the efficacy of cancer immunotherapy.

16 Jul 2024

New Microbe Offers Economical Solution for Synthetic Biological Experiments

Cornell University researchers have created a new version of a microbe to compete economically with E. coli – a bacteria commonly used as a research tool due to its ability to synthesize proteins – to conduct low-cost and scalable synthetic biological experiments.

14 Feb 2024

New Technique Revolutionizes the Construction of Synthetic Chromosomes

A groundbreaking new technique invented by researchers at the USC Dornsife College of Letters, Arts and Science may revolutionize the field of synthetic biology.

26 Dec 2023

Could A Small Flower Hold The Key to More Stable Peptide Drugs?

Taking inspiration from a small purple flower found in the tropics, University of Bath scientists have successfully created a new tool that could help to create more stable, efficient and cost-effective drugs.

29 Nov 2023

Researchers Advance the Breeding of High-Resistant Starch Rice

Researchers have demonstrated that the loss of function of two paralogous starch biosynthesis genes increases the amount of resistant starch (RS) in cooked rice.

8 May 2023

Study pinpoints a splicing deregulation that causes therapeutic vulnerability in pediatric AML

Pediatric acute myeloid leukemia or pAML is a childhood blood cancer, one that has proved confounding to clinicians and researchers, with a high relapse rate and relatively few identified genetic mutations (compared to the adult version) that might explain its cause.

8 Mar 2023

Gaining insights into human disease biology through CRISPR platforms

In this interview, we speak with Laralynne Przybyla about how she is utilizing CRISPR platforms to understand human disease biology in greater detail.

From Society for Laboratory Automation and Screening (SLAS) 7 Feb 2023

CRISPR technology to improve the efficacy of immunotherapy

Using CRISPR technology for the first time, researchers have inserted genes that enable immune cells to concentrate their attack on cancer cells, potentially sparing healthy cells and boosting the effectiveness of immunotherapy.

14 Nov 2022

Genetic options help researchers transmit rust resistance from one plant to another

Stem rust is a major disease in wheat crops around the world, and outbreaks are expected to become more prevalent in upcoming climate change scenarios.

12 May 2022

National DNA Day 2022: an interview with Professor Matthew Cobb

To celebrate National DNA Day 2022, we spoke to science communicator Professor Matthew Cobb.

From The University of Manchester 25 Apr 2022

VectorBuilder to expand with $500 million ‘Gene Delivery Research and Manufacturing Campus

VectorBuilder Inc. has announced the construction of a new R&D and manufacturing center in Guangzhou, China.

From VectorBuilder 12 Apr 2022

Researchers identify and clone a key gene that confers stripe rust resistance in bread wheat

Pests and diseases result in the loss of one-fifth of the global wheat harvest each year, which is enough to make around 290 billion loaves of bread. Resolving the persistent problem of the fungal rust diseases that attack wheat could help ensure future food security.

15 Mar 2022

Cloning News and Research

Scientists Build Live African Swine Fever Virus From Synthetic DNA Using CRISPR

New Insights into How B Cells Strategically Clone High-Affinity Antibodies

Harbour BioMed and Insilico Collaborate on Advanced AI-Driven Antibody Discovery

Scientists Create First Healthy Mice with Two Fathers

Discovery of Efficient Glycosyltransferases for Pterocarpan Glycoside Biosynthesis

Unveiling IRF1's Influence on Cancer Progression and Treatment Using Histology and Flow Cytometry

New Microbe Offers Economical Solution for Synthetic Biological Experiments

New Technique Revolutionizes the Construction of Synthetic Chromosomes

Could A Small Flower Hold The Key to More Stable Peptide Drugs?

Researchers Advance the Breeding of High-Resistant Starch Rice

Study pinpoints a splicing deregulation that causes therapeutic vulnerability in pediatric AML

Gaining insights into human disease biology through CRISPR platforms

CRISPR technology to improve the efficacy of immunotherapy

Genetic options help researchers transmit rust resistance from one plant to another

National DNA Day 2022: an interview with Professor Matthew Cobb

VectorBuilder to expand with $500 million ‘Gene Delivery Research and Manufacturing Campus

Researchers identify and clone a key gene that confers stripe rust resistance in bread wheat

Capturing the mechanisms underlying evolvability in a new framework

INTEGRA’s VOYAGER offers effective pipetting for plant-based transient expression and bacteriocin testing applications

Scientists identify gene with the largest impact on seed protein in soybean

Stem Cells eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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