Constipation News and Research

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Constipation is a condition in which stool becomes hard, dry, and difficult to pass, and bowel movements don’t happen very often. Other symptoms may include painful bowel movements, and feeling bloated, uncomfortable, and sluggish.

Unveiling the Clinical Significance of Microbial Load in Human Health

Scientists built a new machine-learning model to predict microbial load — the density of microorganisms in the guts — and used it to explain how microbial load plays an essential role in disease-microbiome relationships.

14 Nov 2024

Nature-Inspired Approach Accelerates Folding of Cysteine-Rich Peptides for Drug Discovery

Certain types of peptides and microproteins for drug discovery research can be made more efficiently and quickly using a reaction solvent that helps mimic nature's way.

25 Mar 2024

Study Shows How Sensory Neurons Control Gastrointestinal Tracts

Gastrointestinal and digestive issues impact roughly 3 million people across the United States alone, and that number is growing.

4 Aug 2023

New model, C. elegans, helps pursue research on Parkinson's disease

A tiny worm called the C. elegans is enabling scientists to explore the emerging theory that Parkinson's disease starts in the gut.

1 Mar 2023

Adults struggling with chronic constipation benefit from a vibrating capsule

A vibrating capsule designed to stir the colon to action appears to double the ability for adults struggling with debilitating chronic constipation to defecate more normally and without drugs, researchers report.

22 Feb 2023

Blastocystis can promote or disrupt gut health, study finds

The gut microbiota contains trillions of bacteria that can promote health or cause disease under different conditions.

14 Feb 2023

Oral difelikefalin could reduce the intensity of itch in patients with notalgia paresthetica

Notalgia paresthetica-;a nerve disorder characterized by a persistent itch in the upper back-;is a common and underdiagnosed condition worldwide.

9 Feb 2023

Studying the association between gut microbe and Parkinson’s disease

A new study by the University of Surrey suggests that Parkinson’s disease may begin in the gut and pass on to the brain.

From University of Surrey 18 Jan 2023

Coffee found to have a stimulating effect on some digestive processes

A new scientific review, published in Nutrients, highlights coffee's effects on digestion and the gut, and its impact on organs involved in digestion.

19 Jan 2022

Microbiome discovery may help improve treatment for patients facing gut damage

University of Calgary researchers probing the gut -; "the inner tube of life" -; have for the first time discovered specific factors in its workings that in the future may help improve treatment for patients facing gut damage or gastrointestinal disease.

15 Nov 2021

Research reveals how foodborne infections protect the gut's nervous system

A simple stomach bug could do a lot of damage. There are 100 million neurons scattered along the gastrointestinal tract-;directly in the line of fire-;that can be stamped out by gut infections, potentially leading to long-term GI disease.

1 Nov 2021

Drug company pipelines are developing new molecules to help people safely shed extra weight

Drugs that promise to help people lose weight have had a checkered past, such as the infamous fen-phen that was pulled from the market in 1997 after reports of heart valve damage.

21 Oct 2021

Researchers discover that existing drug can enhance memory

A group of scientists identified that a prevailing drug for treating constipation might boost an individual’s capability to think with better clarity.

4 Oct 2021

Researchers generate thyroid mini-organs in the lab

Hormones produced by the thyroid gland are essential regulators of organ function. The absence of these hormones either through thyroid dysfunction due to, for example, irradiation, thyroid cancer or autoimmune disease or thyroidectomy leads to symptoms like fatigue, feeling cold, constipation, and weight gain.

12 Mar 2021

Consumption of high doses of vitamin D supplements is unnecessary

In humans, vitamin D is formed in the skin following its exposure to sunlight. In comparison to the body's own formation of vitamin D, dietary consumption generally makes up only a relatively small proportion of the vitamin D supply to the body.

21 Oct 2020

Early introduction of gluten may prevent coeliac disease in children

Introducing high doses of gluten from four months of age into infants' diets could prevent them from developing coeliac disease, a study has found.

29 Sep 2020

Disrupted circadian rhythms in older adults linked to increased risk of Parkinson's disease

Older men who have a weak or irregular circadian rhythm guiding their daily cycles of rest and activity are more likely to later develop Parkinson's disease, according to a new study by scientists at the UC San Francisco Weill Institute for Neurosciences who analyzed 11 years of data for nearly 3,000 independently living older men.

16 Jun 2020