DNA Sequencing News and Research

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Integrative Taxonomy Uncovers Cryptic Daisy Species

Sometimes plants are sufficiently similar to one another that the procedures used by 18th-century scientist Carl Linnaeus for distinguishing species are insufficient.

14 Nov 2024

Unraveling the Spatial Complexity of Gene Expression with Seq-Scope

A new method, developed by University of Michigan researchers, creates images that are worth many gigabytes of data, which could revolutionize the way biologists study gene expression. Seq-Scope, developed by Jun Hee Lee, Ph.D., Hyun Min Kang, Ph.D., and their colleagues, was first described in Cell in 2021 as the first method to analyze gene expression at sub micrometer-scale spatial resolution.

1 Nov 2024

Next-Generation Sequencer Enhances Genetic Research at UT Arlington

The North Texas Genome Center (NTGC) at UT Arlington is getting an upgrade in the form of a next-generation genetic sequencer that will allow researchers to study genetic links between health and disease at a large scale.

16 Oct 2024

Scientists Successfully Map the Entire Fruit Fly Brain

A team of scientists supported by the National Institutes of Health (NIH)'s The BRAIN Initiative, including Davi Bock, Ph.D., Associate Professor of Neurological Sciences at UVM's Robert Larner, M.D. College of Medicine, recently made a substantial advancement in neurobiological research by successfully mapping the entire brain of Drosophila melanogaster, more commonly known as the fruit fly.

3 Oct 2024

A Novel Genetic Inference Method for Detecting Rare Disease Variants

Undiagnosed cases of Long QT syndrome have been found, thanks to an inventive examination of shared genomic sequences, which is a sign of distant “relatedness” and can cause irregular heart rhythms, fainting, and sudden cardiac death.

30 Sep 2024

Ancient Genomes Reveal Long-Term Genetic Stability in Southernmost Africa

Around 13 individuals, who died between 1,300 and 10,000 years ago, had their genomes reconstructed by a team of researchers from the University of Cape Town (South Africa) and the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, using analysis of human remains found in the southern African rock shelter.

20 Sep 2024

Gut Microbiota Modulates Rotavirus Vaccine Effectiveness

Scientists at Georgia State University's Institute for Biomedical Sciences have shown that some gut flora can reduce the effectiveness of the rotavirus vaccine.

27 Aug 2024

High-Resolution Spatial Transcriptomics at Lower Cost

A novel spatial transcriptomics method that could revolutionize tissue sample gene expression profiling.

7 Aug 2024

St. Jude Scientists Reveal Role of Non-Coding DNA Variants in Childhood Leukemia

St. Jude Children's Research Hospital scientists have identified specific DNA variants in the non-coding regions of the genome contributing to chemotherapy resistance in acute lymphoblastic leukemia (ALL).

2 May 2024

Largest Plant DNA Study Ever Unveils Flowering Plant Tree of Life

The most up-to-date understanding of the flowering plant tree of life is presented in a new study published today in the journal Nature by an international team of 279 scientists, including three University of Michigan biologists.

25 Apr 2024

Enhancing Drug Discovery Through Automated Protein Labeling

Exact protein observation in cells is crucial for many scientific fields, but it has proven to be a difficult technical task, particularly in living cells where each protein needs to have its fluorescent label applied separately.

22 Apr 2024

Genomic Research Unravels Arabica Coffee's Ancient Origins

The key to growing coffee plants that can better resist climate change in the decades to come may lie in the ancient past.

16 Apr 2024

New Virus Offers Hope for Amphibians Ravaged by Fungus

A fungus devastating frogs and toads on nearly every continent may have an Achilles heel. Scientists have discovered a virus that infects the fungus, and that could be engineered to save the amphibians.

4 Apr 2024

New Research Rewrites Bird Family History

An immense meteor spelled doom for most dinosaurs 65 million years ago. However, not all perished. In the aftermath of the extinction event, birds—technically dinosaurs themselves—prospered.

2 Apr 2024

Researchers Track the Genomic Interactions Between Tasmanian Devils and Cancer

Over the past 30 years, Australia's Tasmanian devil population has been afflicted with an infectious cancer that has pushed the species to near extinction.

29 Mar 2024

RNA-Seq Unveils Molecular Subtypes for Tailored Pediatric B-ALL Treatment

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, representing more than 30% of all pediatric cases.

31 Jan 2024

Implications of the KMAP Ocean Gene Catalog 1.0

The greatest investigation of ocean DNA reveals the diverse world of ocean bacteria. The KMAP Global Ocean Gene Catalog 1.0, an open-source database containing over 317 million gene groups, has the potential to stimulate biotechnology innovation and reveal the function of marine microbes in reducing global warming and preserving human and environmental health.

17 Jan 2024