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New Research Examines the Role of Skeletal Stem Cells in Bone Growth and Regeneration

Researchers at UTHealth Houston have been awarded an $8.1 million grant by the National Institutes of Health (NIH) to examine skeletal stem cells as potential drivers of craniofacial bone diseases and deformities. The study is led by Noriaki Ono, DDS, PhD, associate professor of orthodontics, and diagnostic and biomedical sciences at UTHealth Houston School of Dentistry.

14 Oct 2024

Unlocking the Mysteries of Repeat Expansion in Genetics

Research led by scientists at Queen Mary University of London is heralding in a new era for genetic sequencing and testing.

3 Oct 2024

Utah Scientists Begin New Project to Map Epigenetic Changes Across the Human Genome

The Human Genome Project changed everything. A map of the entire human sequence of DNA was the starting point for an enormous number of discoveries, from disease genes to how humans evolved.

12 Aug 2024

Study Uncovers a Biological Explanation for Long-Term Memories

Whether it's a first-time visit to a zoo or when we learned to ride a bicycle, we have memories from our childhoods kept well into adult years.

27 Jun 2024

Genetic Insights into Coffee Consumption and Health Implications

Coffee drinking is a heritable habit, and one that carries a certain amount of genetic baggage.

20 Jun 2024

Genetic Analysis Sheds Light on the Role of Ribosomal DNA Copy Number in Inflammation and Disease

Ribosomal DNA (rDNA) is present in hundreds of copies in the genome, but has not previously been part of genetic analyses.

16 May 2024

Embryonic Cells Pressed into Organizers: Mechanism Unveiled

A collaboration between research groups at the University of California, TU Dresden in Germany and Cedars-Sinai Guerin Children's in Los Angeles has identified a mechanism by which embryonic cells organize themselves to send signals to surrounding cells, telling them where to go and what to do.

4 Apr 2024

New Insights Into the Microbiome's Influence on Kidney Stone Risk

A new study from Lawson Health Research Institute and Western University published in the journal Microbiome has found changes in the microbiome in multiple locations in the body are linked to the formation of kidney stones.

21 Dec 2023

The Adaptable World of Dendritic Cells in Immunity

Dendritic cells play a pivotal role within the mammalian immune system, being distributed throughout the human body.

31 Oct 2023

Stem Cells Used to Create Tooth Enamel in the Lab

Organoids have now been created from stem cells to secrete the proteins that form dental enamel, the substance that protects teeth from damage and decay.

16 Aug 2023

A Common Diabetes Drug Helps Prevent Muscle Atrophy and Muscular Fibrosis

You might not think of diabetes when you think of muscle function. But a common diabetes drug that regulates blood sugar can also prevent muscle atrophy and muscular fibrosis-;which can help the elderly bounce back faster from injury or illness.

26 Jul 2023

T cells are Sensitive to Genetic Disturbances Within Mitochondrial Power Plants

All cells have their own power plants, called mitochondria. There are often more than 100 mitochondria per cell and each possesses their own genome, which in turn contains genes responsible for energy production.

7 Jul 2023

Altered Anti-Nausea Drug can Penetrate Cells and Provide Sustained Pain Relief

Altering the chemical properties of an anti-nausea drug enables it to enter an interior compartment of the cell and provide long-lasting pain relief, according to a new study led by researchers at NYU College of Dentistry's Pain Research Center.

23 May 2023

Researchers Identify Genes Responsible for Craniofacial Dysmorphology in Down Syndrome

Researchers at the Francis Crick Institute, King's College London and University College London have shed light on the genetics behind changes in the structure and shape of the face and head in a mouse model of Down Syndrome.

27 Apr 2023

Astrocytes in the Brain may Play a Key Role in Regulating Information

Long thought of as "brain glue," the star-shaped cells called astrocytes-;members of a family of cells found in the central nervous system called glial that help regulate blood flow, synaptic activity, keep neurons healthy, and play an important role in breathing.

3 Apr 2023

Chloride ions evoke taste sensation by binding to sweet taste receptors

Humans perceive five basic taste sensations: sweet, umami, bitter, salty, and sour. Specific foods trigger taste recognition of these sensations through the activation of different receptors in our taste buds.

24 Mar 2023

Study suggests new strategy for treating arrhythmogenic cardiomyopathy

University of Utah Health scientists have corrected abnormal heart rhythms in mice by restoring healthy levels of a protein that heart cells need to establish connections with one another.

20 Mar 2023

Experts unravel a vast network that shows how cells adjust in real-time to withstand stresses

Every minute of every day, our body adapts to meet the needs of each moment. When we binge on carbs, exercise, or become sick, chemical reactions inside our cells switch on, slow down, or shift strategy so that we have the energy and strength we need.

14 Mar 2023

Researchers use artificial human skin to block invasive tumor growth in skin cancer model

By using artificial human skin, a research group from the University of Copenhagen have managed to block invasive growth in a skin cancer model.

27 Jan 2023

New 3D organoid model reveals a possible biological target for treating GEJ cancers

Researchers at Johns Hopkins Medicine say they have created a laboratory-grown three-dimensional "organoid" model that is derived from human tissue and designed to advance understanding about how early stages of cancer develop at the gastroesophageal junction (GEJ) — the point where the digestive system's food tube meets the stomach.

2 Dec 2022