Drug Delivery News and Research

RSS

Drug delivery is a term that refers to the delivery of a pharmaceutical compound into the body. Most common methods of delivery include the preferred non-invasive oral (through the mouth), nasal, pneumonial (inhalation), and rectal routes. Much research is now focussing on nanotechnology as a drug delivery method.

Bioengineered Bacteria with Mussel-Like Adhesion Could Clean Up Plastic

Researchers at Rice University have created bioengineered microbes with strong adhesion that have the potential to revolutionize environmental cleanup by drawing on nature's genius for adhesives, the sticky power of mussels.

8 Oct 2024

Breakthrough Nanoparticle Therapy Boosts Immune Response Against Aggressive Pancreatic Cancer

Innovative use of lipid nanoparticles to deliver immune agonists shows promise in activating anti-tumor immunity in pancreatic ductal adenocarcinoma models.

9 Sep 2024

Insights into Peptide Clumping Could Transform Drug Design and Material Science

Scientists from China have investigated how short peptide chains aggregate together in order to deepen our understanding of the process, which is crucial for drug stability and material development.

4 Sep 2024

RNA Interference Drugs Offer Faster, More Effective Alternative to Traditional Drug Discovery

Alnylam's RNA interference platform accelerates drug discovery by targeting RNA transcripts, addressing complex diseases with innovative therapeutic strategies.

28 Aug 2024

Effective Plasmid DNA Delivery Achieved with Zwitterionic Polymer Complex

Researchers from Tokyo Metropolitan University have created a new drug delivering molecule, a zwitterionic polymer complex that can help get plasmid DNA inside cells when injected into skeletal muscle, a crucial step in the expression of therapeutic RNA and proteins. The new compound effectively bound to plasmid DNA without affecting its structure. Injected into mouse muscles, the team observed widespread gene expression, promising applications to treatments of serious muscle diseases.

29 Jul 2024

Revolutionizing Biological Drug Delivery with Cell's Transit System

Each cell in the body has its own unique delivery system that scientists are working on harnessing to move revolutionary biological drugs -; molecules like proteins, RNA and combinations of the two -; to specific diseased parts of the body.

17 Jul 2024

Artificial Intelligence Drives Breakthroughs in Drug Discovery, Reducing Costs and Timelines

Researchers discussed using deep generative AI models and their diverse algorithms in de novo drug design.

12 Jul 2024

Ultrasound-Triggered Nanodroplets for Targeted Drug Delivery

Conventional drug delivery is often like cracking a nut with a sledgehammer. Whether the drug is swallowed, injected, inhaled, or absorbed through the skin, it ultimately diffuses to most parts of the body, including those where it isn’t needed – or where it even might cause harm.

22 Jun 2024

3D Cell Cultures Improve Drug Screening Accuracy but Show Lower Efficacy for Anti-Cancer Drugs

The existing knowledge on monolayers and spheroid-based cell cultures, including the constituent compounds, and the difference in efficacy during drug screening, especially for anti-cancer drugs targeting cytoskeletal dynamics and cell cycles.

21 Jun 2024

Scientists Achieve Autonomous Control of Microscopic Machines

Tohoku and Kyoto University researchers have successfully created a DNA-based molecular controller that controls molecular robot building and disassembly autonomously.

17 Jun 2024

Stem cell-based kidney chip revolutionizes disease modeling and research

An organ-on-chip system containing a kidney glomerulus using human-induced pluripotent stem cells and an ultrathin membrane.

17 Jun 2024

Johns Hopkins Scientists Engineer Synthetic Cells to Mimic Symmetry Breaking

In a feat aimed at understanding how cells move and creating new ways to shuttle drugs through the body, scientists at Johns Hopkins Medicine say they have built a minimal synthetic cell that follows an external chemical cue and demonstrates a governing principle of biology called "symmetry breaking."

14 Jun 2024

Mesenchymal stem cell-derived exosomes carrying vincristine sulfate are effective in killing cancer stem cells

Whether loading vincristine sulfate into mesenchymal stem cell-derived exosomes could improve the targeted delivery of the drug specifically to cancer stem cells.

21 May 2024

Single-Molecule Study Reveals Unexpected Role of Protein Stiffness in Nuclear Transport

The degree of softness or rigidity in specific regions of proteins can affect how quickly or slowly those proteins enter the nucleus, according to research from the Francis Crick Institute and King's College London.

14 May 2024

Localized Delivery Minimizes Side Effects of Immunotherapy

Cancer is the monster of the society.. The American Cancer Society reports that over 600,000 Americans lost their lives to cancer in the previous year. Medical progress has been shaped by the unwavering quest to understand this complex disease, leading to the development of less invasive yet highly effective treatment procedures.

22 Apr 2024

Enzymatic Cocktail Outperforms Antibiotics Against Mycobacteria, Including TB

A recent study published in Microbiology Spectrum, a journal of the American Society for Microbiology, demonstrates that an enzymatic cocktail has the capability to eliminate various mycobacterial species of bacteria, including those responsible for tuberculosis.

28 Mar 2024

Drug Delivery News and Research

Further Reading

Bioengineered Bacteria with Mussel-Like Adhesion Could Clean Up Plastic

Breakthrough Nanoparticle Therapy Boosts Immune Response Against Aggressive Pancreatic Cancer

Insights into Peptide Clumping Could Transform Drug Design and Material Science

RNA Interference Drugs Offer Faster, More Effective Alternative to Traditional Drug Discovery

Effective Plasmid DNA Delivery Achieved with Zwitterionic Polymer Complex

Revolutionizing Biological Drug Delivery with Cell's Transit System

Artificial Intelligence Drives Breakthroughs in Drug Discovery, Reducing Costs and Timelines

Ultrasound-Triggered Nanodroplets for Targeted Drug Delivery

3D Cell Cultures Improve Drug Screening Accuracy but Show Lower Efficacy for Anti-Cancer Drugs

Scientists Achieve Autonomous Control of Microscopic Machines

Stem cell-based kidney chip revolutionizes disease modeling and research

Johns Hopkins Scientists Engineer Synthetic Cells to Mimic Symmetry Breaking

Mesenchymal stem cell-derived exosomes carrying vincristine sulfate are effective in killing cancer stem cells

Single-Molecule Study Reveals Unexpected Role of Protein Stiffness in Nuclear Transport

Localized Delivery Minimizes Side Effects of Immunotherapy

Enzymatic Cocktail Outperforms Antibiotics Against Mycobacteria, Including TB

SpaceX Returns Vital Life Science Research Sponsored by the ISS National Lab

Tailored Nanoparticles Deliver siRNA to Reduce Neuroinflammation in Alzheimer's Disease Models

Unleashing the Power of Melanin in Space for Next-Gen Biomaterials

New Methods to Modify Molecular Structure Could Lead to More Tailored Drugs

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Latest in Genomics