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ORNL Scientists Develop Fluorescent Biosensor to Track RNA in Plants

Scientists at Oak Ridge National Laboratory have developed a first-ever method of detecting ribonucleic acid, or RNA, inside plant cells using a technique that results in a visible fluorescent signal.

16 Apr 2025

Researchers Develop STITCHR to Insert Whole Genes Without Unwanted Mutations

Investigators from Mass General Brigham and Beth Israel Deaconess Medical Center have developed STITCHR, a new gene editing tool that can insert therapeutic genes into specific locations without causing unwanted mutations.

12 Apr 2025

Scientists Capture Dynamic Process of Chromatin Remodeling in Action

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can also lead to cancer and other diseases.

7 Apr 2025

Novel Bio-Conjugation Method Achieves High Efficiency and Stability for Protein Modification

A group of researchers from the Pohang University of Science and Technology Department of Materials Science and Engineering, under the direction of Professor Seung Soo Oh and Dr. Hyesung Jo, have created a novel method that allows for the accurate modification of particular proteins in intricate biological settings.

27 Mar 2025

How B Cells Know When to Mutate—and When to Chill

Study reveals B cells suppress mutations during rapid division, enhancing immune response and offering critical insights for vaccine and treatment development.

27 Mar 2025

New Discovery Sheds Light on C. Diff's Survival Mechanism in the Gut

The pathogen C. diff - the most common cause of health care-associated infectious diarrhea - can use a compound that kills the human gut's resident microbes to survive and grow, giving it a competitive advantage in the infected gut.

26 Mar 2025

Non-Active Site Mutations Drive Enzyme Adaptation to Low Temperatures

Enzymes initially developed in high-temperature environments and subsequently adapted to cooler conditions as the Earth underwent a cooling phase.

26 Mar 2025

MIT Scientists Use Light to Control Cell Movement in Starfish

Life takes shape with the motion of a single cell. In response to signals from certain proteins and enzymes, a cell can start to move and shake, leading to contractions that cause it to squeeze, pinch, and eventually divide.

25 Mar 2025

Researchers Capture Breakthrough Images of Cellulose Synthesis in Living Plant Cells

In a groundbreaking study on the synthesis of cellulose – a major constituent of all plant cell walls – a team of Rutgers University-New Brunswick researchers has captured images of the microscopic process of cell-wall building continuously over 24 hours with living plant cells, providing critical insights that may lead to the development of more robust plants for increased food and lower-cost biofuels production.

24 Mar 2025

Engineered Yeast Offers Sustainable Way to Produce D-Lactic Acid from Methanol

Great recipes require the perfect combination of ingredients - biotechnology recipes are no exception.

22 Mar 2025

First-Ever Molecular Movie Shows DNA Unzipping Mechanism in Action

Scientists at the University of Leicester have captured the first detailed "molecular movie" showing DNA being unzipped at the atomic level – revealing how cells begin the crucial process of copying their genetic material.

22 Mar 2025

RNA-Based Active Agents Successfully Shield Plants from Cucumber Mosaic Virus

New RNA-based active agents reliably protect plants against the Cucumber mosaic virus (CMV), the most common virus in agriculture and horticulture. They were developed by researchers at the Martin Luther University Halle-Wittenberg (MLU).

20 Mar 2025

Visualizing the Fundamental Process of DNA Strand Separation

The exact moment DNA starts to unravel has been seen by scientists for the first time, exposing a chemical process that is essential for DNA to be the molecule that codes for all life.

20 Mar 2025

Bispecific antibodies for SARS-CoV-2 variant neutralization

Bispecific antibodies targeting multiple SARS-CoV-2 sites offer enhanced neutralization against emerging variants, advancing COVID-19 treatment strategies.

14 Mar 2025

Low-Cost, Flexible Protein Detection Platform for Global Health

Chemical and biomolecular engineers at Georgia Tech have created a plug-and-play platform for the detection of disease protein biomarkers that is straightforward, adaptable, and user-friendly, eliminating the need for expensive laboratory equipment.

10 Mar 2025

Novel Enzyme for Synthesizing β-1,2-Galactooligosaccharides

Carbohydrate chains, also known as glycans, are intricate sugar-like molecules that are crucial for various biological functions and structures within human bodies.

7 Mar 2025

Understanding TEFM's Role in mtDNA Stability

Mitochondrial deoxyribonucleic acid (mtDNA) is vital for cellular energy production and the overall functionality of cells.

6 Mar 2025

Macrophages Use Bacterial Debris To Fine-Tune Immune Responses

Findings reveal macrophages' role in immune modulation through bacterial metabolites, paving the way for improved therapies for infections and inflammation.

6 Mar 2025

Scientists Unveil Molecular Process of Polymerase Theta in Cancer Cells

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code.

4 Mar 2025

Unveiling the Role of NUDIX Hydrolase in Fungal Infection

Researchers from The Australian National University (ANU), in partnership with scientists from Germany and the United States, have identified a potent “weapon” employed by numerous pathogenic fungi to infect staple food crops like rice and corn. This discovery may lead to novel approaches for enhancing global food security.

28 Feb 2025