Fracture News and Research

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Living Microbes Unearthed in 2-Billion-Year-Old Rock

Pockets of microbes have been found living within a sealed fracture in 2-billion-year-old rock. The rock was excavated from the Bushveld Igneous Complex in South Africa, an area known for its rich ore deposits. This is the oldest example of living microbes being found within ancient rock so far discovered.

4 Oct 2024

LINE-1 RNA from Ancient Viruses Promotes Bone Repair

Around half of the human genome is composed of DNA fragments originating from ancient viruses. These "transposable elements" (TEs) are now known to play various roles in modulating gene expression and disease development.

8 Aug 2024

New Mechanism Regulating Tumor Growth in the Skeleton Identified

Tumor cells are known to be fickle sleeper agents, often lying dormant in distant tissues for years before reactivating and forming metastasis. Numerous factors have been studied to understand why the activation occurs, from cells and molecules to other components in the so-called tissue microenvironment.

11 Aug 2023

New CAR T Strategy Offers a Dual-Targeting Mechanism to Fight Bone Metastatic Prostate Cancer

Prostate cancer frequently metastasizes to the bone and is incurable. Moffitt Cancer Center researchers are working to identify new treatment options for this subset of patients.

4 May 2023

Key Hox genes control stem cells involved in bone formation and repair

A new study discovered that genes that have long been known to regulate bone formation before birth also govern bone healing later in life.

From New York University (NYU) 21 Mar 2023

Gaining insights into the muscle damage protective effect

Loss of muscle strength can be one of the most damaging outcomes when someone is unable to move a part of their body for a long period of time.

2 Mar 2023

Mice study sheds light on why tissues often fail to regenerate from muscle-loss injuries

Tissues often fail to regenerate from traumatic muscle-loss injuries such as gunshot wounds and car accidents, and new research in mice from the University of Michigan sheds light on why.

6 Apr 2022

Research reveals pathways controlling osteocyte development

Osteocytes are seen within bone tissue. They are cells with tree-like projections known as dendrites vital for receiving communication from other cells.

4 Nov 2021

$Mesenchymal stem cells with enhanced fracture healing abilities identified$

Mesenchymal stem cells with enhanced fracture healing abilities identified

Mesenchymal stem cells (MSCs) are anticipated to harbor great potential in the area of regenerative medicine, which aims at restoring damaged tissues.

8 Oct 2021

$Loss of enzymatic processes can increase the risk of bone fracture$

Loss of enzymatic processes can increase the risk of bone fracture

When enzymatic processes decline inside the body, they can increase the risk of bone fracture in a person.

8 Jan 2021

Longitudinal study identifies many genetic markers linked to bone mineral accrual

A multidisciplinary team of researchers led by Children's Hospital of Philadelphia has discovered several genetic markers associated with bone mineral accrual, which could ultimately help identify causes of eventual osteoporosis earlier in life through genetic testing.

7 Jan 2021

New research opens up potential target for treating bone disorders

New research has discovered a cell type that governs the way bones form and maintain themselves, opening up a potential target for future therapies for bone disorders like osteoporosis.

23 Nov 2020

Oxytocin can help control and prevent osteoporosis

Oxytocin, produced by the hypothalamus and sometimes known as the "love hormone" for its involvement in pair bonding and orgasm, can be a strong ally in the control and prevention of osteoporosis, according to a study by scientists at São Paulo State University in Brazil.

11 Aug 2020

Novel genetic measure could improve screening for osteoporosis

An international team of scientists has developed a novel genetic measure that could dramatically improve how doctors assess the risk of sustaining a fracture due to osteoporosis or fragility.

22 Jul 2020

New study can help treat metabolic and genetic bone diseases

A team of researchers, headed by Kanazawa University, has demonstrated that a tiny fish can potentially stop painful genetic and metabolic bone diseases. The study was recently published in the Communications Biology journal.

15 Jul 2020