Lassa Virus News and Research

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Lassa virus or Lassa viral haemorrhagic fever is an acute illness of 1-4 weeks duration that occurs in West Africa. Though first described in the 1950s, the virus causing the disease was not identified until 1969. The virus is a single-stranded RNA virus belonging to the virus family Arenaviridae. Lassa fever is known to be endemic in Guinea (Conakry), Liberia, Sierra Leone and parts of Nigeria, but probably exists in other West African countries as well.

GWAS Identifies Key Genetic Factors for Lassa Fever Susceptibility and Severity

While combing through the human genome in 2007, computational geneticist Pardis Sabeti made a discovery that would transform her research career.

9 Feb 2024

New antibody "cocktail" may help counter the Lassa virus

The finding, made with the use of the Advanced Photon Source, shows a new way to exploit monoclonal antibodies to subvert the "shield" of the virus, potentially paving the way for new therapies.

20 Mar 2023

Scientists unravel the structure of octopus-like Lassa viral polymerase

Endemic in Western African countries, Lassa virus is transmitted to humans through food or household items that are contaminated with the urine or faeces of Mastomys rats.

7 Dec 2021

Study shows how viruses steal genetic signals from hosts to expand their own genomes

Scientists have demonstrated that a large class of viruses, such as the influenza viruses, expand their genomes by stealing genetic signals from their hosts.

19 Jun 2020