Lymphoma News and Research

RSS

Lymphoma is cancer that begins in cells of the immune system. There are two basic categories of lymphomas. One kind is Hodgkin lymphoma, which is marked by the presence of a type of cell called the Reed-Sternberg cell. The other category is non-Hodgkin lymphomas, which includes a large, diverse group of cancers of immune system cells. Non-Hodgkin lymphomas can be further divided into cancers that have an indolent (slow-growing) course and those that have an aggressive (fast-growing) course. These subtypes behave and respond to treatment differently. Both Hodgkin and non-Hodgkin lymphomas can occur in children and adults, and prognosis and treatment depend on the stage and the type of cancer.

QRICH1 Protein Found to Control T Cell Activation in Cancer and Autoimmune Diseases

In a study of the immune systems of mice, scientists at Johns Hopkins Medicine say they have found a new role for a protein, QRICH1, which could become a target for drugs to dial up or down the activation of T cells to fight cancers and autoimmune diseases.

9 Apr 2025

DNA Aptamers Offer Precision Attack Against Leukemia Stem Cells

Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that seed cancer relapses, researchers at the University of Illinois Urbana-Champaign report.

4 Apr 2025

Fusion Proteins Offer New Path for Antibody Generation in Disease Research

The Food and Drug Administration has approved more than 100 monoclonal antibodies to treat a range of diseases. Other antibodies are used by physicians to diagnose conditions or by scientists to advance research projects.

26 Mar 2025

New CRISPR Tool Reveals Key Lymphoma Genes

This study presents an optimized CRISPR-Cas12a system for large-scale genetic screening, revealing critical genes involved in lymphoma development and therapy.

7 Feb 2025

CRISPR-Engineered Fat Cells Show Promise in Preclinical Cancer Models

Cancer is rarely discussed in the same breath as liposuction or plastic surgery.

5 Feb 2025

Mapping the Human Virome to Uncover Links Between Viruses and Health

You, my friend, are what scientists call a "holobiont"- an organism made up of human cells and the multiplicity of microscopic species living inside you and on your body.

27 Jan 2025

New computational strategy enables design of drug-induced protein interactions

A novel geometric deep learning framework designs ligand-specific protein binders, enhancing therapeutic potential in cell therapies and synthetic biology.

22 Jan 2025

Inflammasome Helps Block Malignancy in Blood Stem Cells

A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity, according to a preclinical study by Weill Cornell Medicine investigators.

17 Jan 2025

Researchers Develop Strategy to Boost Pharmaceutical Production in CHO Cells

An international team of researchers led by the University of California San Diego has developed a new strategy to enhance pharmaceutical production in Chinese hamster ovary (CHO) cells, which are commonly used to manufacture protein-based drugs for treating cancer, autoimmune diseases and much more.

16 Jan 2025

Unveiling the Impact of Antigen History on CAR-T Cell Function

The memory of previous interactions with bacteria, viruses, and other antigens is carried by some CAR-T cells that have been engineered to fight cancer and other conditions, according to research from the University of Colorado Anschutz Medical Campus.

3 Jan 2025

Scientists Discover Key to Overcoming Cancer's Evasion Tactics

A cunning culprit that aids cancer cells in avoiding CAR T cell therapy has been identified by researchers at City of Hope®, one of the biggest and most cutting-edge cancer research and treatment organizations in the United States, with a comprehensive cancer center in Los Angeles that is ranked among the top five cancer centers in the country by US News & World Report.

18 Dec 2024

Stanford Researchers Develop New Approach to Make Cancer Cells Self-Destruct

Our bodies divest themselves of 60 billion cells every day through a natural process of cell culling and turnover called apoptosis.

28 Nov 2024

Unveiling the Epigenetic Landscape of Blood Cancers

In recent years, biomedical laboratory research has undergone tremendous change, to the extent that computers have frequently replaced test tubes.

27 Nov 2024

A Closer Look at CAR T-Cell Therapy — Successes, Challenges, And Future

Chimeric antigen receptor T-cell therapy enhances immune response against cancer, with promising results in hematological malignancies and ongoing advancements.

13 Nov 2024

Understanding the Dynamics of Stem Cells

Age influences stem cell survival and immune diversity, according to new research on the long-term dynamics of transplanted stem cells in a patient’s body.

1 Nov 2024

Researchers Identify Mechanism of Immune Suppression in Ovarian Cancer

Researchers at Weill Cornell Medicine have shown that ovarian cancers disable immune cells and prevent them from attacking by cutting off the energy source that T cells rely on.

24 Oct 2024

CRISPR and Antibodies Offer New Hope for Improving CAR-T Cell Therapy Outcomes

Mayo Clinic researchers mined the molecular foundations of cancer and uncovered a new reason chimeric antigen receptor (CAR-T cell therapy) fails in some patients.

13 Sep 2024

Light-Activated Macrophages Show Increased Appetite for Cancer Cells

The body has a veritable army constantly on guard to keep us safe from microscopic threats from infections to cancer.

13 Aug 2024

Study Shows the Ability of Protein 'Signatures' to Predict Onset of 67 Diseases

Research on thousands of proteins measured from a drop of blood demonstrates the ability of proteins to predict the onset of many diverse diseases.

24 Jul 2024

New Research Aims to Improve CAR-T Cell Therapy Effectiveness

CARISMa scientists at Goethe University Frankfurt introduced innovative CAR therapy that recognizes and specifically kills tumor cells. This cancer therapy is the focus of new federally funded LOEWE research.

1 Jul 2024