Neuroblastoma News and Research

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Neuroblastoma is cancer that arises in immature nerve cells and affects mostly infants and children.

Innovative Approach Reveals Brain Evolution Through Ancient DNA Methylation

This research introduces a novel method for inferring DNA methylation patterns in non-skeletal tissues from ancient specimens, providing new insights into human evolution.

21 Nov 2024

Study Shows How Genetic Variations Can Enhance Cancer Drug Effectiveness

By exploiting the genetic variation in cancer cells, an already approved cancer drug demonstrated enhanced effects against cancer cells in specific patient groups.

15 Nov 2024

High-throughput screening identifies potential drugs for low-grade serous ovarian cancer

In a recent study, researchers used high-throughput drug screening to identify potential therapeutic targets and novel treatments for low-grade serous ovarian cancer (LGSOC), offering hope for more effective and personalized therapies.

26 Sep 2024

Unlocking the Secrets of Childhood Cancer Genetics

Scientists have revealed a fresh insight into the genetic pathway of childhood cancer, providing new potential for personalized treatment.

15 May 2024

Targeting RNA Modifications: A Novel Approach for Neuroblastoma Treatment

Neuroblastoma is a common pediatric cancer that originates in developing nerve cells outside the brain.

6 May 2024

Study Unveils Dual Role of 7-DHC in Ferroptosis and Cancer Cell Survival

Cell death is fundamental to life and, thus, healthy aging. In the realm of cellular biology, ferroptosis (a form of programmed cell death) has emerged not only as a focal point of research for its potential in eliminating cancer cells, but also its role in a plethora of other diseases, including neurodegenerative diseases such as Alzheimer's disease, eye diseases such as Retinitis pigmentosa and age-related macular degeneration, as well as ischemia, cardiovascular disease, liver disease, acute kidney injury and inflammation.

2 Feb 2024

AI Program Reveals Cellular Neighborhoods in Cancer Microenvironments

A novel AI-powered program has been developed by researchers at Children's Hospital of Philadelphia (CHOP) to assist in comprehending how various cells arrange themselves into certain tissues and communicate with one another.

9 Jan 2024

Lactate Signaling Found to Be Critical for Neuronal Differentiation

Scientists at Tohoku University have discovered the critical role that lactate plays in helping neural stem cells develop into specialized neurons, a process dubbed neuronal differentiation.

25 Jul 2023

RNA Regulatory Mechanism Involving Stress Granules Directly Regulates Alzheimer’s Development

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 10, entitled, "Stress granules sequester Alzheimer's disease-associated gene transcripts and regulate disease-related neuronal proteostasis."

2 Jun 2023

Randomness governs the responsiveness of tumor cells to chemotherapy

According to a recent study done by the Garvan Institute of Medical Research, cancer cells have an inbuilt unpredictability in their capacity to respond to chemotherapy, which is another tool in their armory for fighting treatment.

6 Mar 2023

Fastest-evolved regions of the human genome diverged rapidly after split from chimpanzee ancestor

A team of Duke researchers has identified a group of human DNA sequences driving changes in brain development, digestion and immunity that seem to have evolved rapidly after our family line split from that of the chimpanzees, but before we split with the Neanderthals.

24 Nov 2022

New method combines AI and microfluidics to easily barcode individual cells

An innovative new method for more efficient and accurate barcoding of individual cells could help realize faster diagnosis of diseases.

From University of Exeter 21 Dec 2021

Genetic makeup of neuroblastoma shows marked spatial and temporal variability

Tumors are heterogeneous, which means that different parts of the same tumor can be genetically distinct. This phenomenon, known as intratumor heterogeneity, is steadily gaining in significance within the field of cancer research.

13 Dec 2021

New study shows how neuroblastoma cells deal with rapid division

The cells of a certain tumor type, called neuroblastoma, divide very rapidly. This rapid division can have potentially fatal consequences for them. A new study shows how neuroblastoma cells deal with this dilemma.

1 Dec 2021

Natural killer cells target breast cancer using the body’s immune system

In a recent study, researchers investigated how natural killer cells target breast cancer using the body's own immune system.

18 Jun 2021

New study shows why some children get secondary leukemia after neuroblastoma treatment

Researchers from the Wellcome Sanger Institute and the University of Cambridge discovered that in children with neuroblastoma—a tumor of immature nerve cells—platinum chemotherapy created mutations in the genome that might lead to leukemia in some children later on.

31 May 2021

Customized tumor cell vaccine produces active immune response in melanoma, neuroblastoma models

A pre-clinical study for melanoma and neuroblastoma shows that a customized tumor cell vaccine technique that targets Myc oncogenes coupled with checkpoint therapy produces an active immune response that bypasses antigen selection and immune privilege.

5 Apr 2021