Oncogene News and Research

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An oncogene is a gene that, when mutated or expressed at high levels, helps turn a normal cell into a tumor cell.

Study Reveals How Chronic Immune Signaling Can Promote Cancer

Along with defending against pathogens, the body's innate immune system helps to protect the stability of our genomes in unexpected ways -; ways that have important implications for the development of cancer, researchers at Memorial Sloan Kettering Cancer Center (MSK) are discovering.

6 Nov 2024

High-throughput screening identifies potential drugs for low-grade serous ovarian cancer

In a recent study, researchers used high-throughput drug screening to identify potential therapeutic targets and novel treatments for low-grade serous ovarian cancer (LGSOC), offering hope for more effective and personalized therapies.

26 Sep 2024

Lipids Found to Play Key Role in Cancer Immune Evasion

Cancer cells seldom start off stealthy. Quite to the contrary, they announce their presence to the immune system by planting chemical red flags right on their membranes.

18 Sep 2024

Breakthrough Nanoparticle Therapy Boosts Immune Response Against Aggressive Pancreatic Cancer

Innovative use of lipid nanoparticles to deliver immune agonists shows promise in activating anti-tumor immunity in pancreatic ductal adenocarcinoma models.

9 Sep 2024

A Landmark Study Reveals the Widespread Existence of DNA i-Motifs

Innovative study of DNA's hidden structures may open up new approaches for treatment and diagnosis of diseases, including cancer.

30 Aug 2024

The Hidden Link Between Cell Membrane Damage and Cellular Senescence Revealed

Researchers from the Okinawa Institute of Science and Technology (OIST) along with the researchers from University of Tokyo, Nagoya University, and Nagoya City University, found that disruption to the cell membrane accelerates cellular senescence or cell aging.

23 Feb 2024

RNA-Seq Unveils Molecular Subtypes for Tailored Pediatric B-ALL Treatment

Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, representing more than 30% of all pediatric cases.

31 Jan 2024

Novel Activation Mechanism for First Identified Oncogene

In the late 1970s, the link between the c-Src gene and cancer was unveiled, marking the identification of the inaugural oncogene.

1 Nov 2023

Targeted MicroRNA-34a Therapy Shows Promise in Slowing Tumor Growth in Mice

A new cancer therapy developed by Purdue University researchers attacks tumors by tricking cancer cells into absorbing a snippet of RNA that naturally blocks cell division.

5 Sep 2023

Liver Cancers With Key Epigenetic Alteration Tend to Have a Poor Clinical Prognosis

Researchers at the Josep Carreras Leukaemia Research Institute, led by Dr. Manel Esteller, have discovered a key epigenetic alteration that anticipates the clinical course of liver cancer.

17 May 2023

Identifying Lung Cancer Patients Who May Not Respond Well to Immunotherapy by MYC Gene Activation

Lung cancer patients who may not react well to immunotherapy (ICB) could be identified by the oncogenic activation of MYC, an important gene in the development of cancer.

17 Apr 2023

Researchers Show How a Virus can Induce Cleavage of Human Chromosome 11 to Cause Cancer

The Epstein-Barr virus (EBV) is easily spread through bodily fluids, primarily saliva, such as kissing, shared drinks or using the same eating utensils.

17 Apr 2023

RXR: A key protein in the balanced production of different blood cells

In the regulation of hematopoietic stem cells—which are the immature stem cells that produce all the blood cell lineages—the cell protein retinoid X receptor (RXR) is an important element.

19 Dec 2022

Molecular motion of “undruggable” proteins reveals drug-binding sites

“Undruggable” proteins, whose structures and roles in disease are known but who appear unable to be targeted by drugs that will bind to them, present some of the hardest problems in disease treatment.

23 Nov 2022

NIH funds research on mRNA vaccines to stop cancer development

The National Cancer Institute at the National Institutes of Health has awarded a multidisciplinary team of Weill Cornell Medicine researchers a five-year $5.7 million grant to support a center dedicated to creating messenger RNA (mRNA) vaccines to prevent the development of cancer in at-risk groups.

15 Nov 2022

Drugs used for myelodysplastic syndrome could potentially activate a sleeping oncogene

Hypomethylating agents (HMA) are currently used as a first-line treatment for patients with myelodysplastic syndrome (MDS) - a group of disorders where there is insufficient production of healthy mature blood cells in the bone marrow - and increasingly in other diseases, but their mechanism of action remains unclear.

From National University of Singapore (NUS) 27 May 2022

Oncogene News and Research

Further Reading

Study Reveals How Chronic Immune Signaling Can Promote Cancer

High-throughput screening identifies potential drugs for low-grade serous ovarian cancer

Lipids Found to Play Key Role in Cancer Immune Evasion

Breakthrough Nanoparticle Therapy Boosts Immune Response Against Aggressive Pancreatic Cancer

A Landmark Study Reveals the Widespread Existence of DNA i-Motifs

The Hidden Link Between Cell Membrane Damage and Cellular Senescence Revealed

RNA-Seq Unveils Molecular Subtypes for Tailored Pediatric B-ALL Treatment

Novel Activation Mechanism for First Identified Oncogene

Targeted MicroRNA-34a Therapy Shows Promise in Slowing Tumor Growth in Mice

Liver Cancers With Key Epigenetic Alteration Tend to Have a Poor Clinical Prognosis

Identifying Lung Cancer Patients Who May Not Respond Well to Immunotherapy by MYC Gene Activation

Researchers Show How a Virus can Induce Cleavage of Human Chromosome 11 to Cause Cancer

RXR: A key protein in the balanced production of different blood cells

Molecular motion of “undruggable” proteins reveals drug-binding sites

NIH funds research on mRNA vaccines to stop cancer development

Drugs used for myelodysplastic syndrome could potentially activate a sleeping oncogene

Study shows polymersome can effectively deliver PARP1 siRNA to treat breast cancer

Researchers discover a unique origin of severe pediatric brain cancer

Kras oncogenes use genetic reprogramming to drive tumorigenesis

Study shows how skin cells act as a firewall against cancer

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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