Prion News and Research

RSS

New Insights into How Mutant p53 Promotes Tumor Growth

Research from the Federal University of Rio de Janeiro (UFRJ) and the National Institute of Science and Technology for Structural Biology and Bioimaging (INBEB) in Brazil has uncovered a critical mechanism by which mutations in the p53 protein-;a key tumor suppressor known as the "guardian of the genome"-;turn other proteins into cancer-promoting agents

17 Sep 2024

Novel Epigenetic Tool CHARM Offers Hope for Prion Disease Treatment

In a new study in mice, researchers introduce "CHARM," a compact and versatile epigenetic editor that can be used to silence prion protein throughout the brain.

28 Jun 2024

Misfolded Proteins: How They Damage Neurons and Cause Neurodegeneration

Neurodegenerative diseases are characterized by the deposition of clumped proteins in the brain and progressive neuronal cell death.

5 Dec 2023

Prion Protein Forms Dynamic Liquid Condensates to Regulate Copper Ions

In an innovative research article published in Science Advances, scientists from the Federal University of Rio de Janeiro (UFRJ) and the German Center for Neurodegenerative Diseases (DZNE-Berlin) illuminate the intricate interplay between the prion protein and copper ions in the physiopathology of live cells.

4 Dec 2023

Interactions between plasma miRNAs and cognitive performance in males

Cognitive decline brought on by aging is a precursor to dementias like Alzheimer’s and can have a significant impact on a person’s ability to carry out essential daily tasks.

16 Sep 2022

Discovery may lead to a better understanding of prion and other neurodegenerative diseases

Prion diseases, such as Creutzfeldt-Jakob Disease (CJD), are fast-moving, fatal dementia syndromes associated with the formation of aggregates of the prion protein, PrP.

23 Dec 2021

Tough protein connects directly with neurons to cause damaging inflammatory reaction in the brain

Neuroinflammatory diseases, including Alzheimer's disease and traumatic brain injury, have been linked to deposits of a tough protein known as fibrin, derived from the blood clotting factor fibrinogen.

9 Nov 2021

Viral diseases likely to contribute to neurodegeneration, says study

Scientists from DZNE revealed that certain viral diseases can contribute to neurodegeneration.

21 Oct 2021

Prions may help yeast cope with rapidly changing environmental conditions

Prions are proteins found in the brain and familiar for their role in causing disease.

23 Sep 2021

Study unravels new aspects of prions causing untreatable neurodegenerative conditions

A new study achieved the highest-ever resolution imaging of an infectious prion, offering atomic-level data of how these abnormal proteins assemble.

25 Aug 2021

Research reveals Alzheimer’s protein accumulates inside nerve cells

Experimental research has shown that amyloid-beta, the Alzheimer’s protein, accumulates within nerve cells.

23 Aug 2021

Novel agonistic effect of polyphenol compound could treat amyloidosis, other metabolic disorders

Reportedly, Curcumin has several physiological activities, which include anti-inflammatory, anti-oxidation, anti-amyloid, and anti-cancer properties.

1 Mar 2021

Study provides insight into the structure of prion proteins responsible for diseases

Prion diseases are a group of rapidly progressive, fatal and infectious neurodegenerative disorders affecting both humans and animals: Bovine Spongiform Encephalopathy (BSE) or 'mad cow' disease is one of the most famous since in 1996 scientists found that the agent responsible for the disease in cows, is the same agent responsible for the so-called variant Creutzfeldt-Jakob Disease (vCJD), a disease affecting humans.

22 Feb 2021

Prion News and Research

New Insights into How Mutant p53 Promotes Tumor Growth

Novel Epigenetic Tool CHARM Offers Hope for Prion Disease Treatment

Misfolded Proteins: How They Damage Neurons and Cause Neurodegeneration

Prion Protein Forms Dynamic Liquid Condensates to Regulate Copper Ions

Interactions between plasma miRNAs and cognitive performance in males

Discovery may lead to a better understanding of prion and other neurodegenerative diseases

Tough protein connects directly with neurons to cause damaging inflammatory reaction in the brain

Viral diseases likely to contribute to neurodegeneration, says study

Prions may help yeast cope with rapidly changing environmental conditions

Study unravels new aspects of prions causing untreatable neurodegenerative conditions

Research reveals Alzheimer’s protein accumulates inside nerve cells

Novel agonistic effect of polyphenol compound could treat amyloidosis, other metabolic disorders

Study provides insight into the structure of prion proteins responsible for diseases

Researchers study how membraneless organelles form and organize themselves

Researchers receive $2.6 million grant to examine tau-glycan interactions involved in Alzheimer's disease

Study shows chameleon-like protein can alter human brain

Protective anti-prion antibodies found in humans

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Latest in Genomics