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Innovative Genomic Technology Uncovers Mechanisms of Marjolin's Ulcer

Researchers utilized specialized genomic technology at the University of Calgary to enhance our understanding of Marjolin's ulcer (MU), a rare, highly aggressive skin cancer that affects chronic wounds that can often arise from established scars like those caused by severe burns.

29 Oct 2024

Key Regulator of Heart Repair

UCLA researchers identified the protein GPNMB as a key regulator in the heart’s healing process following a heart attack.

28 Oct 2024

Study Reveals Immune Cells' Role in Lung Scarring After Viral Infections

Investigators involved in a multicenter study co-led by Cedars-Sinai discovered a pathway by which immune cells prevent the lungs' protective barrier from healing after viral infections like COVID-19.

5 Sep 2024

Study Identifies Key Macrophage Subpopulations in MASH Progression and Regression

Formerly known as nonalcoholic steatohepatitis, metabolic dysfunction-associated steatohepatitis (MASH) is an inflammatory disease characterized by liver scarring or fibrosis that progressively impairs liver function.

23 Aug 2024

New Study Links Keloid Formation to Microbiome Imbalance

A study explores the microbiome of keloids, which are treatment-resistant raised scars. Some wounds heal completely; some wounds leave a scar; and some wounds leave a noticeable raised and growing bump larger than the original wound called a keloid.

1 Aug 2024

Integrated Cellular Map of Heart Fibrosis Unlocks New Treatment Avenues

Scientists at the Victor Chang Cardiac Research Institute in Australia have produced a first of its kind integrated map of heart cells which unlocks the process of cardiac fibrosis – a major cause of heart failure.

24 Jun 2024

How Tumor-Associated Fibrosis Shapes Immune Responses

Immunotherapy is based on harnessing a person's own immune system to attack cancer cells. However, patients with certain tumors do not respond to these therapies and it remains unclear why.

5 Jun 2024

CAR Peptide Accelerates Tissue Repair and Minimizes Scarring

Accelerating tissue injury repair while preventing the formation of less functioning scar tissue in the injured areas is one of the main objectives of medical science.

15 Feb 2024

Understanding How Antibiotic Resistance Occurs in Pneumonia

Scientists at the University of Sheffield have uncovered an evolutionary gateway that enables pneumonia cells to develop resistance to antibiotics.

3 Oct 2023

Researchers Identify Key Cells Involved in the Process of Cartilage Regeneration in Lizards

A team of researchers from the Keck School of Medicine of USC have published the first detailed description of the interplay between two cell types that allow lizards to regenerate their tails.

11 Aug 2023

Scientists Develop Nanofiber Scaffold to Grow Retinal Cells

Scientists have found a way to use nanotechnology to create a 3D 'scaffold' to grow cells from the retina –paving the way for potential new ways of treating a common cause of blindness.

31 Jul 2023

Modulation of ERK Signaling Could be Used to Stimulate Regeneration

Why do some animals regenerate lost tissues after injury while others don't? Researchers from the lab of Kerstin Bartscherer (Osnabrück University and formerly Hubrecht Institute) and Ashley Seifert (University of Kentucky) studied spiny mice, which have a remarkable regenerative capacity, to answer this question.

26 Apr 2023

Using Cellular Reprogramming to Make the Heart Function Like New Again

A recent study using mice has revealed a way to turn back the clock after heart attack. The researchers behind the work used RNAs to instruct cells in an injured heart to eliminate scar tissue and recreate cardiac muscle, allowing the heart to function like new again.

20 Apr 2023

New type of neural implant could restore limb function to amputees

Researchers have developed a new type of neural implant that could restore limb function to amputees and others who have lost the use of their arms or legs.

23 Mar 2023

Single mechanosensitive protein shown to contribute to fibrosis in multiple organs

Researchers from Kyushu University have found how a single mechanosensitive protein induces the process that thickens and scars tissue, known as fibrosis. The protein, called VGLL3, was shown to contribute to fibrosis in multiple organs.

23 Mar 2023

SMART researchers develop the world's first microneedle-based drug delivery technique for plants

Researchers from the Disruptive & Sustainable Technologies for Agricultural Precision (DiSTAP) Interdisciplinary Research Group (IRG) of Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, and their collaborators from Temasek Life Sciences Laboratory (TLL) and Massachusetts Institute of Technology (MIT), have developed the first-ever microneedle-based drug delivery technique for plants.

14 Mar 2023

Bean genome sequencing to boost nutritional quality

The faba bean genome, which has been sequenced for the first time and published in Nature on March 8th, 2023, is more than four times as large as the human genome at 13 billion bases.

From University of Reading 10 Mar 2023

Experts sequence the faba bean genome

The faba bean genome, which at 13 billion bases is more than four times the size of the human genome, has been sequenced for the first time and is published today (08 March 2023), in Nature. This is an extraordinary technical achievement and crucial to efforts to breed beans with optimum nutritional content and sustainability of production.

8 Mar 2023

Understanding how tiny organisms thrive after wildfires

UC Riverside researchers have identified tiny organisms that not only survive but thrive during the first year after a wildfire. The findings could help bring land back to life after fires that are increasing in both size and severity.

8 Feb 2023

Antibody that blocks VEGF-B could be a potential therapeutic option for fatty liver disease

There is currently no drug for treating non-alcoholic fatty liver disease, which affects many people with type 2 diabetes and which can result in other serious liver diseases.

6 Feb 2023