Surgery News and Research

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Tumor Recurrence Prediction from Multi-Omics Information by Deep Learning

MULGONET combines deep learning and multi-omics analysis to predict tumor recurrence, addressing interpretability and enhancing cancer prognosis understanding.

16 Apr 2025

Enhanced Oral Vaccination with Competitive Gut Bacteria

Researchers are combining vaccination with targeted colonization of the intestine by innocuous microorganisms to combat bacterial infections. This strategy might signal a sea change in the antibiotic crisis.

4 Apr 2025

Scientists Discover Key Genes for Regenerating Sensory Cells in the Ear and Eye

The same genes could hold the key to regenerating cells in the ear and eye, according to a new mouse study from the USC Stem Cell laboratory of Ksenia Gnedeva, PhD, published in the Proceedings of the National Academy of Sciences.

1 Apr 2025

Scientists Develop Off-the-Shelf Vascular Grafts Using Stem Cells

Zhang, J., et al. (2025) Small-diameter artery grafts engineered from pluripotent stem cells maintain 100% patency in an allogeneic rhesus macaque model. Cell Reports Medicine. doi.org/10.1016/j.xcrm.2025.102002.

12 Mar 2025

Tumor Cell Adhesion Could Help Predict Breast Cancer Spread

By assessing how "sticky" tumor cells are, researchers at the University of California San Diego have found a potential way to predict whether a patient's early-stage breast cancer is likely to spread.

6 Mar 2025

Immunotherapy Breakthrough Targets Jumbled Proteins in Glioma

Immune therapy has transformed how cancer is treated, but many tumors continue to evade these treatments, thanks to their resemblance to healthy tissue.

20 Feb 2025

Researchers Uncover Genomic Drivers Behind Aggressive Breast Cancer

Breast cancers can be classified into subgroups that hint at the aggressiveness of the cancer and the likelihood that the patient will experience a recurrence years after their initial diagnosis.

11 Feb 2025

Research Sheds Light on How Obesity Affects Gene Expression in Fat Cells

As many as 40% of Americans are obese, putting them at an increased risk for high blood pressure, diabetes, stroke, heart disease and certain cancers, according to the CDC.

11 Feb 2025

CRISPR-Engineered Fat Cells Show Promise in Preclinical Cancer Models

Cancer is rarely discussed in the same breath as liposuction or plastic surgery.

5 Feb 2025

First Cell Atlas of Focal Cortical Dysplasia Offers New Insights for Treatment

Using a single-cell sequencing technique, Brazilian researchers have created the first cell atlas of focal cortical dysplasia (FCD), a malformation of the cerebral cortex that leads to drug-resistant epilepsy.

31 Jan 2025

Bioengineered Vessels Offer Alternative to Synthetic Grafts for Vascular Repairs

A new type of bioengineered blood vessel showed strong results in treating severe vascular injuries, potentially offering vascular surgeons a better alternative to synthetic grafts when patients' veins aren't suitable for use in repairs.

10 Jan 2025

Single-Cell RNA Sequencing Sheds Light on Craniopharyngioma Tumor Subtypes

Craniopharyngiomas are brain tumors that negatively impact the hormonal function of the nearby pituitary.

17 Dec 2024

"Molecular GPS" Developed to Guide Immune Cells into the Brain and Kill Tumors

Researchers have found a way to program immune cells to attack glioblastoma and treat the inflammation of multiple sclerosis in mice.

6 Dec 2024

Adult Neurogenesis Found to Aid Verbal Learning and Memory

Why do adults make new brain cells? A new study published in Cell Stem Cell provides the first cellular evidence that making new brain cells in adults supports verbal learning and memory, which enables people to have conversations and to remember what they hear.

6 Dec 2024

New Discovery Redefines the Shape of Axons in Mammalian Brain Cells

Biology textbooks may need a revision, say Johns Hopkins Medicine scientists, who present new evidence that an armlike structure of mammalian brain cells may be a different shape than scientists have assumed for more than a century.

3 Dec 2024

New Method for Understanding Brain Function and Dysfunction

An international group of researchers from FutureNeuro, the Research Ireland Centre for Translational Brain Science, and RCSI University of Medicine and Health Sciences have created a novel technique to characterize gene activity in the living human brain.

26 Nov 2024

Chromosome Abnormalities Found in Healthy Women’s Breast Cells

A new study from researchers at The University of Texas MD Anderson Cancer Center finds that, in healthy women, some breast cells that otherwise appear normal may contain chromosome abnormalities typically associated with invasive breast cancer. The findings question conventional thinking on the genetic origins of breast cancer, which could influence early cancer detection methods.

22 Nov 2024

Novel Approach to Isolating and Quantifying EV Cargo for Disease Diagnosis

Parkinson's disease (PD) and Alzheimer's disease (AD) are examples of brain illnesses that begin to develop in patients far earlier than the onset of their initial clinical symptoms.

4 Nov 2024

New Lab-Grown Lip Cells Could Transform Research and Treatment for Disfiguring Lip Conditions

We use our lips to talk, eat, drink, and breathe; they signal our emotions, health, and aesthetic beauty. It takes a complex structure to perform so many roles, so lip problems can be hard to repair effectively. Basic research is essential to improving these treatments, but until now, models using lip cells -; which perform differently to other skin cells -; have not been available.

4 Nov 2024