Toxicology News and Research

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Toxicology is the study of harmful interactions between chemical, physical, or biological agents and biological systems.

Synthetic Microbiome Treatment Prevents C. difficile Infection in Mice

A synthetic microbiome therapy, tested in mice, protects against severe symptoms of a gut infection that is notoriously difficult-to-treat and potentially life threatening in humans, according to a team of researchers at Penn State.

4 Mar 2025

New 3D Lung Model Offers Personalized Aerosol Therapeutic Insights

Respiratory diseases are a challenging problem to treat. Inhalable medicines are a promising solution that depend on the ability to deliver tiny particles known as aerosols to the correct location in the lungs at the correct dosage.

21 Feb 2025

CN Bio Introduces PhysioMimix DILI Assay Kit to Enhance Drug Safety Testing

CN Bio, a leading provider of Organ-on-a-chip (OOC) Systems and solutions that accelerate drug discovery and development workflows, today announced the launch of its PhysioMimix® DILI assay kit: Human 24.

10 Feb 2025

Study Reveals Mechanism Behind T Cells' Cancer-Killing Power in Hypoxia

Immune checkpoint blockades, or ICBs, have revolutionized treatment for various advanced cancers. However, their effectiveness has plateaued due to therapeutic resistance that renders tumor-infiltrating lymphocytes, or TILs, ineffective.

16 Dec 2024

Unmasking the Molecular Mechanisms of Melanoma

LMU researchers have discovered how the interplay between a key protein and an endolysosomal ion channel promotes tumor development in skin cancer.

24 Nov 2024

Exploring Drug-Microbiome Interactions in Complex Bacterial Communities

Many human medications can directly inhibit the growth and alter the function of the bacteria that constitute our gut microbiome.

25 Sep 2024

New Gene Editing Tool Shows Promise for Treating Diseases

Bacterial and archaeal CRISPR-Cas systems, comprising protein and RNA components, were initially developed as a natural defense mechanism against invading viruses.

24 Sep 2024

New Method Detects Peroxymonocarbonate and Its Role in Cellular Responses

High levels of carbon dioxide (CO2) in the atmosphere can alter not only the climate of our planet but also the functioning of our cells.

24 Sep 2024

FAM110A's Dual Role: Orchestrating Microtubule-Actin Interactions in Mitosis

An international research collaboration, led by Prof. Dr. Robert Grosse (Centre for Integrative Biological Signalling Studies and Institute of Clinical and Experimental Pharmacology and Toxicology, University of Freiburg), Dr. Libor Macurek (Institute of Molecular Genetics, Czech Academy of Sciences, Prague) and Dr. Zdenek Lansky (Institute of Biotechnology, Czech Academy of Sciences, Prague) has uncovered a new mechanism of the crosstalk between microtubules and actin cytoskeleton during cell division and revealed unique characteristics of the previously unexplored protein FAM110A.

17 Jul 2024

New Research Into the Impact of Microplastics and Nanoplastics on Human Health is Urgently Required Due to ‘Significant Threat’ to Human Health

A new metastudy published in Cambridge Prisms: Plastics by Cambridge University Press, has identified a body of evidence demonstrating the negative impact of microplastics and nanoplastics (MPs and NPs) on human health and identifying the limitations of current research.

20 Mar 2024

Dr. Bartek Rajwa of Purdue University Named Editor-in-Chief of “Cytometry Part A” Journal by the International Society for Advancement of Cytometry

The International Society for Advancement of Cytometry (ISAC) is pleased to announce the appointment of Dr. Bartek Rajwa as the new Editor-in-Chief of “Cytometry Part A – the Journal of Quantitative Cell Science.”

10 Feb 2024

National Korea Maritime and Ocean University Researchers Explore the Impact of Microplastics and Toxin Exposure on Goldfish

Microplastic particles can travel long distances in oceans and are known to carry with them harmful and persistent organic pollutants like benzo[α]pyrene (BaP), a polycyclic aromatic hydrocarbon.

11 Jan 2024

Researchers Redesign the Future of mRNA Therapeutics

Scientists have unearthed that errors in the interpretation of therapeutic mRNA by the cell’s decoding apparatus can incite an inadvertent immune reaction within the body.

7 Dec 2023

Molecular Docking Analysis Unlocks Secrets of Flavonoid Metabolism

In a world where plant-based lifestyles are on the rise, the power of foods such as broccoli, celery, and tofu, which are rich in flavonoids, is becoming clearer.

5 Dec 2023

Researchers Redesign Future mRNA Therapeutics to Prevent Potentially Harmful Immune Responses

Researchers have discovered that misreading of therapeutic mRNAs by the cell’s decoding machinery can cause an unintended immune response in the body.

5 Dec 2023

Broken String Biosciences Closes $15M Series A Funding Round

Broken String Biosciences today announced that it has closed a $15 million Series A investment round, co-led by Illumina Ventures and Mérieux Equity Partners, with contributions from HERAN Partners, and existing investors Tencent and Dieter von Holtzbrinck Ventures.

19 Sep 2023

DiNP Exposure in Early Pregnancy May Cause Birth Defects

We are constantly exposed to phthalates in our environment through plastic products such as storage containers, medical devices, packages, fabrics, and toys. Specifically, di-isononyl phthalate is inevitably becoming a part of our lives. Unfortunately, the impact of DiNP on the establishment and maintenance of pregnancy is largely unknown. In a new study, researchers used mice to understand how DiNP affects pregnancy.

4 Sep 2023

The Prevalence of Fibrinogen Aα-Chain Amyloidosis in Japanese Squirrels

Fibrinogen Aα-chain amyloidosis, a condition previously unknown in animals other than humans, has been shown to be extremely common in Japanese squirrels (Sciurus lis), according to a study conducted by Dr Tomoaki Murakami of the Tokyo University of Agriculture and Technology.

21 Aug 2023

Chemical in Widely Used Sweetener is "Genotoxic", Study Finds

A new study finds a chemical formed when we digest a widely used sweetener is "genotoxic," meaning it breaks up DNA.

1 Jun 2023

Two Bacteria Species Capable of Collapsing Stubborn Class of "Forever Chemicals" Discovered

Chemical and environmental engineering researchers from the University of California, Riverside, have determined two species of bacteria discovered in soil, which collapse a class of stubborn “forever chemicals.” This gives belief in affordable biological clean-up of industrial pollutants.

31 May 2023