Tryptophan News and Research

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Tryptophan is one of the 20 standard amino acids, as well as an essential amino acid in the human diet.

New AI Model ProteinGenerator Revolutionizes Protein Design with Sequence and Structure Integration

Harnessing deep learning, ProteinGenerator designs diverse proteins with specific properties, offering new avenues for drug development and biotechnology.

2 Oct 2024

A Novel Biosensor for Calcium Detection in Fruit Flies, Zebrafish, and Mice

In 2021, the Janelia group leaders reported that they had developed a way to combine Schreiter's engineered protein biosensors and Lavis's bright, fluorescent Janelia Fluor dyes.

23 Sep 2024

Insights into Peptide Clumping Could Transform Drug Design and Material Science

Scientists from China have investigated how short peptide chains aggregate together in order to deepen our understanding of the process, which is crucial for drug stability and material development.

4 Sep 2024

Novel Drug Targets in Gardnerella Vaginalis: A Bioinformatics Approach to Combat Bacterial Vaginosis

A computational approach to identify proteins in G. vaginalis that could be potential drug targets.

20 Aug 2024

Unveiling the Chemical Secrets of Coral Reefs and Insights into Marine Health

What species exist on this coral reef, and how healthy are they?

7 Jun 2024

What Makes Certain Mushrooms 'Magic'?

In a recent study published in the journal Nature Communications, an international research team from various Universities including Hans Knöll Institute investigated the biosynthesis of psilocybin, the primary component of hallucinogenic mushrooms.

17 Apr 2024

New Research Highlights Gut's Role in Preventing Infections

According to a study published in the journal Nature, gut bacteria and a diet high in the amino acid tryptophan can protect against pathogenic E. coli, which can cause severe upset stomach, cramps, fever, intestinal bleeding, and renal failure.

14 Mar 2024

Novel Amino Acid Nanoparticles Offer Hope for Fighting Multi-Drug Resistant Cancers

Amino acids, such as tyrosine and tryptophan, are the fundamental building blocks that make up proteins.

9 Jan 2024

Unlocking the Potential of Lab-Made Hydrogel for Tissue Growth and Medical Applications

A recently developed laboratory-created material imitates human tissue and has the potential to decrease or substitute for the utilization of animal-derived components in biomedical studies.

24 Oct 2023

Sucrose Acts as a Signal Transmitter for Light-Dependent Root Architecture Formation in Arabidopsis

Plant growth is driven by light and supplied with energy through photosynthesis by green leaves. It is the same for roots that grow in the dark – they receive the products of photosynthesis, in particular sucrose, i.e. sugar, via the central transportation pathways of phloem.

31 May 2023

Identifying Drugs to Put the Brakes On Accelerated Aging From HIV Infection, Treatment

Antiretroviral cocktails can make human immunodeficiency virus, or HIV, undetectable and untransmittable, but both the virus and its treatment can also accelerate aging of bone and muscle.

24 May 2023

Eye color genes play important roles in maintaining retinal health

Metabolic pathways consist of a series of biochemical reactions in cells that convert a starting component into other products.

24 Mar 2023

Researchers naturally breed new varieties of popcorn with improved taste, texture and prebiotics

A Nebraska-led coming attraction may soon pop into a global blockbuster. Through a decade-long project supported by Conagra Foods, a University of Nebraska–Lincoln research team led by David Holding has naturally bred new varieties of popcorn that outperform today's most popular kernels in their intrinsic nutritional value and taste.

14 Nov 2022

Researchers optimize a route for two-step synthesis of antiviral plant protectant

Plant viruses are of great variety and harm. Virus disease pandemics and epidemics were estimated to have a global economic impact in the tens of billions of dollars.

3 Mar 2022

A missing link explains how class I molecules evolved from a class II-like origin Major Histocompatibility...

Which came first, MHC class I or MHC class II? For decades, it has been debated which of these two similar classes came first in evolution. Now, Keiichiro Hashimoto and his group at Fujita Health University, Japan, in collaboration with European research groups, have provided an answer to this question in a new article in PNAS.

14 Dec 2021

Persister bacteria manipulate intracellular pH for surviving antibiotic treatment

Decreasing bacterial acidity could help reduce antimicrobial resistance by eliminating bacteria that can survive being treated with antibiotics.

From University of Exeter 21 Jul 2021

Digital tool predicts protein stability in a cheaper, safer, and faster way

A cutting-edge digital tool that will make it cheaper, safer and faster for pharmaceutical companies to predict protein stability - a vital step in the development of new medicines - is being rolled out by scientists from the UK's University of Bath through their spin-out company, BLOC Labs.

From University of Bath 31 May 2021

“Paralyzed” immune cells can be reactivated by drugs in IDH-mutant gliomas

Brain tumor cells with a certain common mutation reprogram invading immune cells. This leads to the paralysis of the body's immune defense against the tumor in the brain. Researchers from Heidelberg, Mannheim, and Freiburg discovered this mechanism and at the same time identified a way of reactivating the paralyzed immune system to fight the tumor.

25 May 2021

Metagenomic sequencing helps examine differences in the gut microbiome after injury

Researchers used metagenomic sequencing to identify variations in virus and bacterial populations that occur following spinal cord injury in mice.

13 May 2021

Researchers develop new cell-based test system to identify immunoregulatory modulators

Our immune system is very successful when it comes to warding off viruses and bacteria. It also recognizes cancer cells as potential enemies and fights them. However, cancer cells have developed strategies to evade surveillance by the immune system and to prevent immune response.

18 Mar 2021