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Scientists Build Live African Swine Fever Virus From Synthetic DNA Using CRISPR

Utilizing CRISPR-Cas9, scientists reconstitute live African swine fever virus from synthetic genomes, accelerating vaccine development for this deadly virus.

2 Apr 2025

Serendipitous Discovery Reveals How Whole-Genome Duplication Drives Evolution

Sometimes, the most significant scientific discoveries happen by accident. Scientists have long known that whole-genome duplication (WGD) - the process by which organisms copy all their genetic material - plays an important role in evolution.

27 Mar 2025

Study Sheds Light on Cell’s Adaptive Response to Stress

The body's cells respond to stress-toxins, mutations, starvation or other assaults-by pausing normal functions to focus on conserving energy, repairing damaged components and boosting defenses.

27 Mar 2025

Researchers Create Yeast Consortium for Efficient Lignan Biosynthesis

Lignans are low molecular weight polyphenolic compounds with important antitumor and antiviral properties.

25 Mar 2025

Engineered Yeast Offers Sustainable Way to Produce D-Lactic Acid from Methanol

Great recipes require the perfect combination of ingredients - biotechnology recipes are no exception.

22 Mar 2025

LUC7 Proteins Play Key Role in RNA Splicing Control

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are cut out and the coding portions are spliced back together.

21 Feb 2025

New Approach to Cancer Treatment Through Nutrient Deprivation

Scientists had previously ignored the cooperative method by which cancer cells obtain nutrients from their surroundings, but it may be a promising target for cancer treatment.

20 Feb 2025

Could Pea-Derived Oligosaccharides Be a Faster, More Sustainable Option For Sour Beer Production?

Raffinose-family oligosaccharides from peas boost sour beer production, improving fermentation efficiency and sensory qualities in the brewing process.

17 Feb 2025

Scientists Discover Hidden Role of RNA Introns in Cellular Stress Response

Scientists have discovered that some tiny segments of RNA thought to be junk instead have a functional role in suppressing production of certain messenger RNAs and appear to help cells respond to oxidative stress.

12 Feb 2025

Mismatch Repair Genes Found to be Key Drivers of Huntington's Disease

A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and triggering downstream pathologies and motor impairment, shedding light on disease mechanisms and potential new ways to develop therapies.

12 Feb 2025

High-Resolution Images Reveal How Cells Discard Faulty Spliceosomes

A sophisticated molecular machine, the spliceosome, ensures the accurate assembly of genetic information from the genome into mature mRNA after it has been transcribed into mRNA precursors.

10 Feb 2025

Unraveling the Role of Cyclin B Docking in Regulating Cell Division

Cell division is essential for the survival of all living organisms, from the simplest yeast to complex human beings.

29 Jan 2025

Researchers Complete Synthetic Yeast Chromosome, Advancing Genome Engineering

This study details the design and optimization of synXVI, a synthetic yeast chromosome, overcoming growth challenges through innovative genomic strategies.

29 Jan 2025

New Consensus Paper Advances Nomenclature for Mitochondria Transfer and Transplantation

Most animal, plant and fungal cells contain organelles called mitochondria. These descendants of a primordial bacterial endosymbiont still preserve distinct genes and are known for their ability to create ATP as chemical energy.

28 Jan 2025

Breakthrough Achieved in Completing the Creation of First Synthetic Yeast Genome

Macquarie University researchers have worked with an international team of scientists to achieve a major milestone in synthetic biology by completing the creation of the final chromosome in the world's first synthetic yeast genome.

23 Jan 2025

New computational strategy enables design of drug-induced protein interactions

A novel geometric deep learning framework designs ligand-specific protein binders, enhancing therapeutic potential in cell therapies and synthetic biology.

22 Jan 2025

Researchers Develop Method to Produce Strigolactones Using Microbial Cell Factories

Sometimes just using a different tool makes the job a whole lot easier. A team of researchers co-led by the University of California San Diego has developed a method to produce a special class of plant hormones, known as strigolactones, at unprecedented levels using microbial cell factories.

17 Jan 2025