Biochemistry

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Synthetic Condensates Turbocharge Protein Production in Bacteria

Biomedical engineers at Duke University have developed a novel synthetic method that enhances bacteria's ability to produce higher quantities of specific proteins, including those that would typically harm them, such as antibiotics.

12 Feb 2025

Study Reveals How Gut Bacteria Influence Brain Protein Modifications

Our guts are home to trillions of bacteria, and research over the last few decades has established how essential they are to our physiology – in health and disease.

11 Feb 2025

Understanding Plant Repair of Light-Damaged Photosystems

More than two billion years ago, cyanobacteria started to produce oxygen in the primarily toxic atmosphere of Earth.

11 Feb 2025

CN Bio Introduces PhysioMimix DILI Assay Kit to Enhance Drug Safety Testing

CN Bio, a leading provider of Organ-on-a-chip (OOC) Systems and solutions that accelerate drug discovery and development workflows, today announced the launch of its PhysioMimix® DILI assay kit: Human 24.

10 Feb 2025

New Study Expands Understanding of Protocell Formation on Early Earth

One leading theory on the origins of life on Earth proposes that simple chemical molecules gradually became more complex, ultimately forming protocells-primitive, non-living structures that were precursors of modern cells.

8 Feb 2025

New Synthesis Method Makes Ibogaine More Accessible for Research

Ibogaine, a psychoactive compound derived from plants, has garnered attention for its anti-addictive and anti-depressant properties.

7 Feb 2025

Engineering Living Materials with Tailored Properties

Researchers from Rice University have identified new sequence-structure-property relationships for tailoring engineered living materials (ELMs), allowing for more precise control over their structure and response to deformation forces such as stretching or compression.

6 Feb 2025

PairMap Method Reduces Drug Discovery Costs and Improves Binding Predictions

Drug discovery is a costly and time-intensive process, with binding free energy calculations between the potential drug molecule and the target being crucial for reducing drug discovery costs, streamlining the process and avoiding dead-end leads

5 Feb 2025

Genetic Map of Yerba Mate Offers Insight into Evolution of Caffeine Biosynthesis

Yerba mate, along with tea and coffee, is one of the world's most popular caffeinated beverages. Widely consumed in South America, this remarkable plant is rich in diverse, bioactive compounds that contribute many health benefits.

5 Feb 2025

New DNA Sequencing Method Revolutionizes Metabolite Measurement

Researchers at the University of Toronto have developed a novel approach to measure metabolites using DNA sequencing.

5 Feb 2025

Danish Protein Analysis to Revolutionize the Biopharma Industry’s Impurity Control

Since 2007, the contract laboratory Alphalyse A/S has developed and refined a new method of impurity analysis in biological pharmaceuticals based on mass spectrometry (MS).

3 Feb 2025

Novel Chemo-Optogenetic Systems Offer Spatiotemporal Precision

A research team at Umeå University has created advanced light-controlled tools that allow for precise regulation of proteins in real time within living cells.

31 Jan 2025

Temperature-Sensitive Protein Enables Non-Invasive Control of Cellular Behavior

Imagine being at a big marquee event at an arena, like the Super Bowl, with the roar of the crowd, the smell of hot dogs, and a sea of jerseys all merging into one chaotic blur.

30 Jan 2025

Coffee's Bitter Taste Linked to Genetics and Roasting Process

Why does coffee taste more bitter to some people than it does to others? Researchers at the Leibniz Institute for Food Systems Biology at the Technical University of Munich have now come closer to answering this question.

30 Jan 2025

High-Throughput Method Reveals the Effects of Active Substances on Cellular Metabolism

Researchers at the University of Basel are able to test in parallel the effects of over 1500 active substances on cell metabolism.

29 Jan 2025

New Lipids Dramatically Improve Gene Therapy and Vaccine Delivery

Every time a shuttle docks with the International Space Station (ISS), a precise and intricate process takes place between the shuttle’s docking system and its counterpart on the station

29 Jan 2025

Mitochondrial Calcium Imbalance Drives Neurodegeneration

Mitochondria are crucial organelles for cellular homeostasis, regulating processes such as ATP production, reactive oxygen species (ROS) management and Ca2+ signaling.

27 Jan 2025

Bacteria Can Degrade PFAS and Its Toxic Byproducts

In the quest to take the "forever" out of "forever chemicals," bacteria might be our ally.

24 Jan 2025

New Method for Engineering GPCRs Opens Pathways for Advanced Drug Development

Proteins are life's engines, powering processes like muscle movement, vision, and chemical reactions.

24 Jan 2025

Synthesizing Inaoside A from Edible Mushroom

Although natural compounds from plants and animals have long been utilized in drug development, the chemical potential of mushrooms is still poorly understood. Inaoside A, a substance obtained from the edible mushroom Laetiporus cremeiporus, has now been effectively synthesized for the first time by Japanese researchers.

24 Jan 2025