Biochemistry

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Foodborne titanium dioxide nanoparticles impact gut microbiota in mice

A common food additive, recently banned in France but allowed in the U.S. and many other countries, was found to significantly alter gut microbiota in mice, causing inflammation in the colon and changes in protein expression in the liver, according to research led by a University of Massachusetts Amherst food scientist.

26 Jun 2020

New approach spurs production of antibiotic or antiparasitic compounds in bacteria

Researchers have developed a method to spur the production of new antibiotic or antiparasitic compounds hiding in the genomes of actinobacteria, which are the source of drugs such as actinomycin and streptomycin and are known to harbor other untapped chemical riches.

26 Jun 2020

Simplified artificial cell sheds light on the dynamics of cellular symmetry

Symmetry and asymmetry are fundamental properties of nature. Seen from above, butterflies have left-right symmetry, while male fiddler crabs show dramatic asymmetry.

26 Jun 2020

Feed additive shows promise to mitigate enteric methane emissions in dairy cows

The enteric methane mitigation potential of 3-nitrooxypropanol (3-NOP) has been confirmed in previous studies. 3-NOP is highly soluble and rapidly metabolized in the rumen.

25 Jun 2020

A metabolic enzyme could be a potential drug target for B cell lymphomas

Scientists at the Sloan Kettering Institute have found that increased activity of a normal metabolic enzyme can lead to cancer.

25 Jun 2020

Researchers discover new druggable pathway linked with tuberous sclerosis

Tuberous sclerosis complex (TSC) is a neurological disorder causing non-cancerous tumors, called cortical tubers, to grow throughout the brain and body, as well as other conditions like epilepsy and autism.

25 Jun 2020

Study shows how the innate immune system fights off toxin-producing bacteria

The innate immune system is the main line of defense against infections caused by microorganisms.

24 Jun 2020

Researchers discover unknown enzyme activity towards human endogenous substrates

Scientists have identified an enzymatic activity towards common drugs as well as significant human endogenous substrates, that was previously not known.

24 Jun 2020

University of Kentucky collaborates with Atomwise to explore potential COVID-19 therapies

The University of Kentucky announced a research collaboration with Atomwise, an industry leader in using artificial intelligence (AI) for small molecule discovery, to explore potential COVID-19 therapies.

24 Jun 2020

Blocking a pair of sugar-transporting proteins slows lung tumor growth

Blocking a pair of sugar-transporting proteins may be a useful treatment approach for lung cancer, suggests a new study in mice and human cells published today in eLife.

24 Jun 2020

Five-minute urine test measures quality of people's diets

Scientists have completed large-scale tests on a new type of five-minute urine test that measures the health of a person's diet, and produces an individual's unique urine 'fingerprint'.

23 Jun 2020

White Paper: Separation and characterization of viruses and antibodies

Postnova Analytics have published an informative new white paper that details how multi-detector Asymmetrical Field Flow Fractionation (AF4) and Electrical AF4 (EAF4) techniques are transforming the separation and characterization of viruses and antibodies.

From Postnova Analytics 23 Jun 2020

Study sheds light on DNA sculpting properties of enigmatic protein

Sometimes, when something is broken, the first step to fixing it is to break it even more. In a recent example, scientists seeking to understand the mechanism of a DNA-repairing enzyme have discovered that the molecule performs its functions by first marking and then further breaking damaged DNA.

22 Jun 2020