Cell Biology

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GET Model Unveils Gene Regulation with Unmatched Accuracy Across Cell Types

GET, a novel computational model, accurately predicts gene activity by analyzing chromatin accessibility and DNA sequences across diverse human cell types.

20 Jan 2025

Deep Sea Foraminifera Species Unveil Secrets of Life in Extreme Environments

Most life on Earth relies on the sun's energy for survival, but what about organisms in the deep sea that live beyond the reach of its rays? A new study led by Woods Hole Oceanographic Institution (WHOI), published in The ISME Journal, sheds light on how a species of foraminifera, single-celled organisms found in almost all marine habitats, thrives in a dark, oxygen-free environment.

17 Jan 2025

Researchers Develop Method to Produce Strigolactones Using Microbial Cell Factories

Sometimes just using a different tool makes the job a whole lot easier. A team of researchers co-led by the University of California San Diego has developed a method to produce a special class of plant hormones, known as strigolactones, at unprecedented levels using microbial cell factories.

17 Jan 2025

Scientists Discover Surprising Directional Flexibility in DNA-Shaping Motors

Scientists from Delft, Vienna, and Lausanne discovered that the protein machines that shape our DNA can switch direction.

17 Jan 2025

Study Unveils Surprising Cause of Brain Cell Death in Huntington's Disease

Scientists at the Broad Institute of MIT and Harvard, Harvard Medical School, and McLean Hospital have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells.

17 Jan 2025

Inflammasome Helps Block Malignancy in Blood Stem Cells

A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity, according to a preclinical study by Weill Cornell Medicine investigators.

17 Jan 2025

Researchers Develop Strategy to Boost Pharmaceutical Production in CHO Cells

An international team of researchers led by the University of California San Diego has developed a new strategy to enhance pharmaceutical production in Chinese hamster ovary (CHO) cells, which are commonly used to manufacture protein-based drugs for treating cancer, autoimmune diseases and much more.

16 Jan 2025

Researchers Develop Method to Visualize Nanocarriers at Single-Cell Level

How can we ensure that life-saving drugs or genetic therapies reach their intended target cells without causing harmful side effects? Researchers at Helmholtz Munich, Ludwig-Maximilians-Universität (LMU) and Technical University Munich (TUM) have taken an important step to answer this question.

16 Jan 2025

Study Reveals Key Ion Channel in Extracellular Vesicles for Cargo Transport

Scientists have revealed the secret to the structural integrity of tiny particles that transport cargo from cell to cell through blood vessels and bodily fluids: special proteins that keep their membranes intact as they negotiate shifting electrical impulses in different biological environments.

16 Jan 2025

Epigenetic Mechanism Controls Placental Blood Vessel Formation

If the development of blood vessels in the placenta is impaired, fetal growth retardation may result. Scientists from the German Cancer Research Center (DKFZ) and the Mannheim Medical Faculty of Heidelberg University discovered that the correct development of functioning blood vessels in the mouse placenta is controlled epigenetically: One of the enzymes that modify gene activity using methyl groups is responsible.

16 Jan 2025

Is Calcium Signaling the Bridge Between Unicellular and Multicellular Life?

Calcium-dependent signaling in S. rosetta uncovers mechanisms of cellular coordination, shedding light on the evolution of multicellularity and sensory systems.

16 Jan 2025

Terumo BCT and FUJIFILM Irvine Scientific Partner to Optimize T Cell Expansion Process

Terumo Blood and Cell Technologies (Terumo BCT), and FUJIFILM Irvine Scientific have announced a strategic collaboration to help accelerate T cell expansion using Fujifilm's PRIME-XV® T Cell Expansion Media on Terumo BCT’s Quantum Flex™ Cell Expansion System. By using systems that work together, this collaboration offers an optimized workflow solution with a ready-to-use process, aimed at reducing the barriers in scaling T cell expansion.

15 Jan 2025

DNA Stretching: Minimizing Thermal Fluctuations for Imaging

The majority of microscopes can only illuminate objects up to a specific size before the smallest details start to blend together.

15 Jan 2025

New Software Reveals Unprecedented Insights into Embryonic Heart Development

Researchers have created a new software program that offers previously unheard-of capabilities for viewing inside 3D pictures.

13 Jan 2025

Tokyo Researchers Develop Antibacterial Surfaces Safe for Cell Culture

Researchers from Tokyo Metropolitan University have created nanostructured alumina surfaces which are strongly antibacterial but can be used to culture cells.

13 Jan 2025

Study Reveals T Cells as Key Players in Complete Viral Infection Control

Scientists from Duke-NUS Medical School and the Singapore General Hospital have discovered that T cells-white blood cells that can destroy harmful pathogens-can completely prevent viral infection, to an extent previously thought only possible due to neutralizing antibodies.

13 Jan 2025

Shade Plants Harness Far-Red Light for Photosynthesis in a Surprising Way

Plants in the shade of other plants receive more light than scientists had previously believed. A team of researchers from Utrecht University and Wageningen University & Research (WUR) describe how, in a recent article in the scientific journal Plant Cell & Environment.

10 Jan 2025

Outer Ears Evolved From Fish Gills Through Unique Genetic Mechanism

The outer ear is unique to mammals, but its evolutionary origin has remained a mystery. According to a new study published in Nature from the USC Stem Cell lab of Gage Crump, this intricate coil of cartilage has a surprisingly ancient origin in the gills of fishes and marine invertebrates.

10 Jan 2025

Research Shows How Sleep Clears Brain Waste

A good night's sleep does more than just help you feel rested-it might literally clear your mind. A new study published January 8 in the Cell Press journal Cell shows how deep sleep may wash away waste buildup in the brain during waking hours, an essential process for maintaining brain health.

10 Jan 2025

Scientists Uncover Circuit Controlling Neuron Migration in Brain Development

The journey of a thousand miles begins with a single step, but for developing neurons, this first step relies on collaboration from multiple signaling pathways.

10 Jan 2025