Genomics

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Discovery of ALAS1's Secret Role Could Boost Cancer Therapy Development

In everyday life, when things turn out the opposite of what you expect, it's usually cause for frustration. In science, it's often the starting point for discovery.

23 Dec 2024

PlantRNA-FM: Bridging the Gap Between RNA Structure and Function

With PlantRNA-FM, researchers can systematically analyze plant RNA, uncovering functional motifs that play key roles in gene expression and stress responses.

23 Dec 2024

New Genetic Link to Autism Identified

New research published in The American Journal of Human Genetics has identified a previously unknown genetic link to autism spectrum disorder (ASD). The study found that variants in the DDX53 gene contribute to ASD, providing new insights into the genetic underpinnings of the condition.

20 Dec 2024

Engineering Yeast Promoters for Biologic Manufacturing

When introducing genes into yeast to make it produce drugs and other useful substances, it is also necessary to reliably switch the production on or off. A Kobe University team found three gene regulation design principles that provide a flexible guideline for the effective control of microbiological production.

19 Dec 2024

Single-Cell RNA Sequencing Sheds Light on Craniopharyngioma Tumor Subtypes

Craniopharyngiomas are brain tumors that negatively impact the hormonal function of the nearby pituitary.

17 Dec 2024

BOOSTER Gene: Unlocking New Potential in Photosynthesis and Crop Productivity

The BOOSTER gene enhances photosynthesis in plants, improving efficiency and productivity under varying light conditions, crucial for agricultural advancements.

17 Dec 2024

Targeting Cancer with Nanoparticle-Delivered Gene Therapy

Scientists are literally shining a laser on the energy centers of cancer cells in an attempt to harm these sources of power and cause widespread cancer cell death.

16 Dec 2024

Researchers Uncover Lamin A's Role in DNA Repair and Premature Aging Disease

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have discovered how a protein called lamin A helps repair the protective barrier around a cell's DNA.

16 Dec 2024

Scientists Discover New Twist in DNA Looping Mechanism

Scientists from the Kavli Institute of Delft University of Technology and the IMP Vienna Biocenter discovered a new property of the molecular motors that shape our chromosomes.

16 Dec 2024

New Genetic Insights into Craniofacial Defects and Embryonic Development

An international team of researchers has identified a key genetic mechanism that regulates the formation and migration of cranial neural crest cells, which are essential for developing facial structures.

16 Dec 2024

Ancient DNA Reveals Neandertal Gene Flow into Modern Humans

Ancient DNA research suggests that our non-African ancestors mixed with Neandertals about 50,000 years ago, resulting in one to two percent Neandertal DNA in non-African modern humans.

14 Dec 2024

New iFlpMosaics Toolkit Enhances Gene Research and Disease Insights

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has developed a comprehensive set of innovative genetic tools and mouse lines, called iFlpMosaics, designed to enhance the study of gene function and its implications in health and disease.

14 Dec 2024

New Look at the Last Universal Common Ancestor

Revising genetic code evolution, this research uncovers early amino acid recruitment patterns and sulfur's significance for understanding extraterrestrial life.

13 Dec 2024

New Study Links Ancient Human Remains from Zlatý kůň and Ranis in Genetic Findings

After modern humans left Africa, they met and interbred with Neandertals, resulting in around two to three percent Neandertal DNA that can be found in the genomes of all people outside Africa today. However, little is known about the genetics of these first pioneers in Europe and the timing of the Neandertal admixture with non-Africans.

13 Dec 2024

Study Reveals Genetic Basis of Sweetpotato Flesh Color Regulation

Sweetpotatoes are an agricultural powerhouse that feeds millions globally. However, their complex genetics make it challenging for breeders to understand and improve traits like yield, disease resistance, and nutritional content. A new study reveals insights into the significance of leveraging "allele dosages" in sweetpotato breeding practices.

13 Dec 2024

Ribosomal Fingerprints: A Novel Approach to Early Cancer Detection

Different types of cancer have unique molecular 'fingerprints' which are detectable in early stages of the disease and can be picked up with near-perfect accuracy by small, portable scanners in just a few hours, according to a study published today in the journal Molecular Cell.

11 Dec 2024