Genomics

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Scientists Identify Crucial Mechanism for Maintaining Neuronal Identity in the Brain

A team of researchers from the Institute for Neurosciences, a joint center of the Spanish National Research Council (CSIC) and the Miguel Hernández University (UMH) of Elche, in collaboration with researchers from Columbia University (New York, USA), has identified a mechanism that regulates the production of two different proteins from the same gene.

24 Mar 2025

How Drug-Resistant Bacteria Use Antimicrobial Tools to Outcompete Others

A drug-resistant type of bacteria that has adapted to health care settings evolved in the past several years to weaponize an antimicrobial genetic tool, eliminating its cousins and replacing them as the dominate strain.

24 Mar 2025

UV Light Reshapes 3D Genome Structure, Altering DNA Repair and Gene Activity

Research shows UV radiation modifies 3D genome structure, affecting DNA damage response and gene activity, offering insights for cancer prevention strategies.

24 Mar 2025

Scientists Unlock the Mechanism Behind piRNA's Defense Against Jumping Genes

Adverse genetic mutations can cause harm and are due to various circumstances. "Jumping genes" are one cause of mutations, but cells try and combat them with a specialized RNA called piRNA.

22 Mar 2025

Programmable Embryoids Provide Insight into Early Development

The earliest days after fertilization, once a sperm cell meets an egg, are shrouded in scientific mystery.

22 Mar 2025

AGD Initiative Drives Progress in Drug Discovery with Sequencing of 250,000 Whole Genomes

Nashville Biosciences LLC (NashBio), a leading clinical and genomic data company and wholly owned subsidiary of Vanderbilt University Medical Center, and global DNA sequencing giant Illumina Inc. today announced that 250,000 whole genomes have been sequenced for the Alliance for Genomic Discovery (AGD) initiative.

22 Mar 2025

New Resource for Improving Pistachio Quality

California generates around $3 billion in economic value from the production of 99% of the country's pistachios. The absence of a high-quality DNA map, however, has contributed to the minor understudies of pistachios.

21 Mar 2025

A Next-Gen CRISPR Tool Just Dropped

Over the past 15 years, developments in the gene-editing technique known as CRISPR-Cas9 have produced significant new understandings of the functions that particular genes play in a variety of disorders.

21 Mar 2025

New Database Provides Insights into snoRNA Expression in Zebrafish

Small nucleolar RNAs (snoRNAs) are non-coding RNA molecules whose role in gene regulation and their association with certain diseases, such as inflammatory bowel disease (IBD) or colorectal cancer, has only recently become known.

20 Mar 2025

Pregnancy Triggers Small Intestine Growth in Mice

Researchers at the Francis Crick Institute have found that the small intestine grows in response to pregnancy in mice. This partially irreversible change may help mice support a pregnancy and prepare for a second.

20 Mar 2025

New Chromosome Identification System Revolutionizes Alfalfa Research

In a recent study, scientists have developed a revolutionary chromosome identification system for alfalfa, one of the world's most economically vital forage crops.

19 Mar 2025

Researchers Develop RNA "Barcoding" Tool to Track Genetic Exchange in Bacteria

In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive antibiotic resistance and even shape entire ecosystems.

19 Mar 2025

Rethinking Cancer: Moving Beyond Genetic Mutations to a Holistic View

It's time for researchers to reconsider the current paradigm of cancer as a genetic disease, argued Sui Huang from the Institute for Systems Biology, USA, and colleagues in a new essay published March 18th in the open-access journal PLOS Biology.

19 Mar 2025

Genetic Research Uncovers a Lost Chapter of Human Evolution

Utilizing sophisticated analyses grounded in complete genome sequences, researchers at the University of Cambridge have uncovered indications that modern humans emerged from a genetic mixing event involving two ancient populations that diverged approximately 1.5 million years ago.

19 Mar 2025

AI Revolutionizes Cell Analysis for Personalized Cancer Treatment

A groundbreaking artificial intelligence (AI)-driven neural network has been developed to swiftly analyze and interpret millions of cells from patient samples, enabling predictions of molecular alterations within tissues.

19 Mar 2025

Scientists Unlock Genetic Secrets of Wild Barley to Improve Crop Yields

An international team of scientists from Australia and China has unveiled the first chromosome-scale genome of a wild barley species, with their findings offering direct implications for more sustainable agriculture and significant yield improvements for Australian grain production.

17 Mar 2025