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Study Reveals Epigenetic Changes in Sperm from Non-Genetic Infertility Causes

How non-genetic factors can induce epigenetic modifications to the sperm and cause male infertility.

3 Jul 2024

Astrocyte Receptor Effects Differ Dramatically Between Sexes

Weill Cornell Medicine scientists have uncovered the first evidence that astrocyte receptors can trigger opposite effects on cognitive function in male and female preclinical models.

31 May 2024

Understanding Prostate Cancer Disparities Through Proteogenomics

Certain proteogenomic signatures in the prostate cancers of men of African and European ancestries were associated with higher risk of metastasis and/or recurrence of the disease, according to a study presented at the American Association for Cancer Research (AACR) Annual Meeting 2024, held April 5-10.

10 Apr 2024

First Whole Genome Sequencing of Male Breast Cancer Reveals Potential Treatment Targets

Male breast cancer has distinct alterations in the tumor genome that may suggest potential treatment targets, according to a study by Weill Cornell Medicine investigators.

5 Mar 2024

Large Study Finds 187 New Genetic Variants Linked to Prostate Cancer

A globe-spanning scientific team has compiled the most comprehensive list of genetic variants associated with prostate cancer risk -; 451 in all -; through a whole-genome analysis that ranks as the largest and most diverse investigation into prostate cancer genetics yet.

10 Nov 2023

Genes may be Responsible for Third of Complex Regional Pain Syndrome Cases

But the condition is less common in men, even though they are more likely to have the 4 genetic variations implicated in heightened risk, suggesting that there may be sex specific causes, say the researchers.

11 Oct 2023

New CAR T Strategy Offers a Dual-Targeting Mechanism to Fight Bone Metastatic Prostate Cancer

Prostate cancer frequently metastasizes to the bone and is incurable. Moffitt Cancer Center researchers are working to identify new treatment options for this subset of patients.

4 May 2023

Prime Target for Male Contraceptive Development Identified

As far as a highly effective, reversible, and non-hormonal male contraceptive for humans and animals is concerned, the discovery of a gene in multiple mammalian species could set the stage.

18 Apr 2023

Scientists Illuminate the Mechanism that Raises and Lowers PSMA Expression in Prostate Cancer

Like the better-known prostate-specific antigen (PSA), prostate-specific membrane antigen (PSMA) is a biomarker that can tell physicians much about a patient's metastatic prostate cancer.

11 Apr 2023

Novel Genes Could Serve as Predictive Biomarkers for PARP Inhibitor Response in Prostate Cancer

Prostate cancer tumors harboring BRCA1/2 mutations are exceptionally sensitive to PARP inhibitors, while genomic alterations in other DNA damage response (DDR) genes are less responsive.

5 Apr 2023

New combination therapy regimen may reduce prostate cancer progression or death by 37%

TALAPRO-2, a study led by Neeraj Agarwal, MD, FASCO, demonstrated that using TALZENNA, in combination with XTANDI, may reduce the risk of disease progression or death by 37%.

20 Mar 2023

An innovative strategy for on-demand contraception for men

An experimental contraceptive drug developed by Weill Cornell Medicine investigators temporarily stops sperm in their tracks and prevents pregnancies in preclinical models. The study, published in Nature Communications on Feb. 14, demonstrates that an on-demand male contraceptive is possible.

16 Feb 2023

Mental health benefits from urban greenness differ for men and women, study shows

Exposure to urban greenness leads to greater mental health benefits for women, although they are less likely to use these green spaces as frequently for reasons mainly related to safety concerns.

1 Aug 2022

Dads' close involvement during adolescence can have a lasting impact on sons' testosterone production

University of Notre Dame Associate Professor of Anthropology Lee Gettler and his collaborators have drawn on data collected over more than 30 years from almost 1,000 men in the Philippines to help shed light on the importance of adolescence and father-son experiences to sons' adult testosterone patterns.

2 Jun 2022

Trial assesses the impact of Mediterranean diet on depression symptoms in young men

Depression is a common mental health condition that affects approximately 1 million Australians each year. It is a significant risk factor for suicide, the leading cause of death in young adults.

10 May 2022

Genetic variants that predict higher blood levels of lipoprotein A linked with prostate cancer risk

A new analysis has uncovered a potential link between higher prostate cancer risk and genetic variants associated with higher bloodstream levels of the cholesterol-transporting molecule lipoprotein A.

28 Jan 2022

Study identifies two proteins as novel markers of aggressive prostate cancer

Prostate cancer is the most commonly diagnosed cancer in men and is among the top five causes of cancer-related death. In most cases, prostate cancer can be successfully treated but there is a group of patients who suffer an aggressive course and often fatal outcome.

23 Dec 2021