Molecular & Structural Biology

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Versatile Molecule with a New Role in Genome Maintenance

A multi-institutional team of researchers from the Georgia Institute of Technology has uncovered a hitherto unidentified function for RNA.

22 Nov 2024

Ancient DNA Unlocks Secrets of European Genetic Adaptation

Leveraging a unique statistical analysis and applying it to ancient DNA extracted from human skeletal remains, a team of researchers from The University of Texas at Austin and the University of California, Los Angeles has revealed new insights into how ancient Europeans adapted to their environments over 7,000 years of European history.

21 Nov 2024

Study Reveals Key Role of Interleukin-38 in Skin Renewal

The mechanisms underlying skin renewal are still poorly understood. Interleukin-38 (IL-38), a protein involved in regulating inflammatory responses, could be a game changer.

19 Nov 2024

Mouse Aging Proteomic Atlas Provides Insight into Age-Related Protein Shifts

With the worldwide population aging at an unprecedented rate, the prevention of age-related diseases has become a prominent issue.

18 Nov 2024

Magnesium-Focused Approach to Curbing Antibiotic Resistance

According to recent estimates, the number of fatal antibiotic-resistant illnesses is expected to increase significantly over the next 25 years.

18 Nov 2024

Comprehensive Proteomic Atlas of Aging in Mice

Preventing age-related illnesses has become a major concern as the global population ages at a never-before-seen rate.

15 Nov 2024

New Insights into the Molecular Basis of Mitochondrial Diseases

A significant finding about the energy production process of human cells has been made by researchers at the Karolinska Institute's Department of Cell and Molecular Biology.

11 Nov 2024

CRISPR Reveals Hidden Functions of Noncoding RNA

Genes contain instructions for protein production, with the central dogma of biology stating that this information flows from DNA to RNA to proteins.

8 Nov 2024

Integrating Multiple Scales to Understand Brain Function

A long-standing goal of neuroscience is to understand how molecules and cellular structures on a microscale give rise to communication between brain regions at the macroscale. A study published in Nature Neuroscience now identifies, for the first time, hundreds of brain proteins that explain inter-individual differences in functional connectivity and structural covariation in the human brain.

1 Nov 2024

Study Reveals How Cells Rearrange Cytoskeletal Structures During Division

A living cell is a bustling metropolis, with countless molecules and proteins navigating crowded spaces in every direction.

30 Oct 2024

Encrypted Peptides Offer Hope Against Antibiotic-Resistant Infections

Researchers have discovered a new class of antimicrobial compounds called encrypted peptides, which could boost the immune system's toolkit to combat infection and counteract the growing problem of antibiotic-resistant bacteria.

29 Oct 2024

Unveiling the Molecular Mechanisms of CRISPR-Cas10's Cellular Shutdown

CRISPR-Cas9 can elegantly and precisely cut away any desired region of DNA and has long been compared to a type of genetic scissors.

29 Oct 2024

3D Structure of Artificial Photosynthetic Antenna Protein Complex Revealed

Humans can do plenty, but plants have an ability we don't: they make energy straight from sunlight, a superpower called photosynthesis. Yet new research shows that scientists are closing that gap.

29 Oct 2024

F-Actin Accumulation Impairs Brain Function in Aging Fruit Flies

Humans aren't the only ones who grow forgetful as they age -; fruit flies do, too. But because fruit flies have a lifespan of only about two months, they can be a useful model for understanding the cognitive decline that comes with aging.

29 Oct 2024

Novel Mechanism for GRB2-SOS1-Mediated Liquid-Liquid Phase Separation

Researchers at Tokyo Metropolitan University have discovered new details about how the proteins GRB2 and SOS1 in cells transmit signals from membrane receptors to nuclei.

28 Oct 2024

Predicting Disease-Causing Protein Interactions with PIONEER

Researchers at Cornell University and Cleveland Clinic developed an open-access computational platform and online database that helps identify targetable interactions between proteins for therapeutic purposes.

25 Oct 2024

Cryo-EM Technology Paves the Way for Major Biological Discovery

Ben Orlando's research talk at MSU's Department of Biochemistry and Molecular Biology in 2019 laid the groundwork for a team effort that had been developing for decades.

25 Oct 2024

New Insights into How TRIM25 Fights RNA Viruses

Human bodies are attacked every single second of every day. The invading agents include bacteria, viruses, parasites, and toxins both living and non-living things that could impair how well bodies work.

25 Oct 2024

Structural Insights into Bacteriophages Open Doors for New Therapeutics

The viruses that infect bacteria are the most abundant biological entities on the planet. For example, a recent simple study of 92 showerheads and 36 toothbrushes from American bathrooms found more than 600 types of bacterial viruses, commonly called bacteriophages or phages.

23 Oct 2024

A Novel Regulator of RNA Processing in Alzheimer's Disease

A research team from the University of Barcelona's Institute of Neurosciences described a novel molecular mechanism that modifies the process of protein synthesis and impacts RNA processing in Alzheimer's patients' brains.

21 Oct 2024