Cell Biology News and Research

Latest Cell Biology News and Research

New study pinpoints key source of T cell "exhaustion"

Custom-made to attack cancer cells, CAR T-cell therapies have opened a new era in the treatment of human cancers, particularly, in hematologic malignancies.

21 Mar 2023

T cell-driven changes in the gut may affect brain function associated with depression

In experiments with mice and humans, a team led by Johns Hopkins Medicine researchers says it has identified a particular intestinal immune cell that impacts the gut microbiome, which in turn may affect brain functions linked to stress-induced disorders such as depression.

21 Mar 2023

Keeping lymph nodes in the body can boost the efficacy of cancer immunotherapy

Cancer treatment routinely involves taking out lymph nodes near the tumor in case they contain metastatic cancer cells.

21 Mar 2023

Blunted inflammatory response could make obese patients more susceptible to severe COVID-19

Individuals who are obese may be more susceptible to severe COVID-19 because of a poorer inflammatory immune response, say Cambridge scientists.

21 Mar 2023

Stickiness of influenza virus may determine the frequency of co-infection

Influenza viruses have an enormous impact in the U.S., with an estimated 25 million illnesses and 18,000 deaths in the 2022-23 flu season alone.

21 Mar 2023

DNA drugs help restore the normal processing of protein-encoding RNA

A protein named TDP-43 has been lost from its normal location in the nucleus of the cell in virtually all persons having amyotrophic lateral sclerosis (ALS) and in up to half of all cases of frontotemporal dementia and Alzheimer’s disease (AD).

From UC San Diego 20 Mar 2023

Macrophages likely to be a potential target for ER+ breast cancer

Most immunotherapies that aim to increase T cell activity are ineffective in treating estrogen receptor-positive (ER+) breast cancer. A new study of invasive ER+ breast cancers led by researchers at the University of Pittsburgh School of Medicine implies that targeting a different type of immune cell called macrophages may be a more effective approach.

From University of Pittsburgh 20 Mar 2023

Perspectives on nucleolar DNA damage response in the fight against cancer

Cancer, which affects so many people each year, relies on proteins to proliferate throughout the body. Scientists are damaging the disease’s protein factories as part of a new tactic to combat the widespread disease.

20 Mar 2023

The protein synthesis mechanism in the Giardia parasite

Cryo-electron microscopy was employed by Uppsala University researchers to reveal information on the protein synthesis mechanism in the parasite Giardia intestinalis, which causes diarrhea. The new findings could help in the development of specific medicines to combat Giardia and other protozoan parasites.

20 Mar 2023

Amide-to-ester substitutions can enhance the membrane permeability of cyclic hexapeptides

Cyclic peptides often exhibit low membrane permeability which can be significantly improved via amide-to-ester substitutions-;as demonstrated by researchers from Tokyo Institute of Technology.

20 Mar 2023

Study discovers the ability of certain blood immune cells to proliferate

The ability of a cell to divide, to proliferate, is essential for life and gives rise to the formation of complex organisms from a single cell.

20 Mar 2023

Immune landscape in invasive ER+ breast cancers reveals a macrophage-driven microenvironment

Most immunotherapies, which aim to boost T cell activity, work poorly in treating estrogen receptor-positive (ER+) breast cancer.

20 Mar 2023

Decreased viral infection severity in females linked to extra copy of epigenetic regulator

It has long been known that viral infections can be more severe in males than females, but the question as to why has remained a mystery – until possibly now.

20 Mar 2023

Delaying paralysis in ALS by using designer DNA drug

In virtually all persons with amyotrophic lateral sclerosis (ALS) and in up to half of all cases of Alzheimer's disease (AD) and frontotemporal dementia, a protein called TDP-43 is lost from its normal location in the nucleus of the cell.

20 Mar 2023

Neoadjuvant dual immunotherapy and chemotherapy improve outcomes in patients with resectable NSCLC

In a Phase II trial led by researchers from The University of Texas MD Anderson Cancer Center, adding ipilimumab to a neoadjuvant, or pre-surgical, combination of nivolumab plus platinum-based chemotherapy, resulted in a major pathologic response (MPR) in half of all treated patients with early-stage, resectable non-small cell lung cancer (NSCLC).

20 Mar 2023

Using a programmable control switch to deliver therapeutic RNA molecules to target cells

Using an RNA sensor, MIT engineers have designed a new way to trigger cells to turn on a synthetic gene.

17 Mar 2023

Genomic analysis shows Ashaninka people are not as homogeneous as previously reported

The Ashaninka are the most numerous Indigenous people living in the rainforests of Peru and Brazil where they inhabit a crucial area between the Andes and sources of the Amazon River. And yet, despite the size of the population and their importance in the past and present, their genetic history has remained understudied.

17 Mar 2023

Losing a productive type of beta cell may contribute to the development of diabetes

Multiple types of beta cells produce insulin in the pancreas, helping to balance blood sugar levels. Losing a particularly productive type of beta cell may contribute to the development of diabetes, according to a new study by Weill Cornell Medicine investigators.

17 Mar 2023

Potential approach to improve solid tumor T cell therapy

Researchers at the Perelman School of Medicine at the University of Pennsylvania have been working on a preclinical study that focuses on a new strategy that uses a “one-two punch” to assist T cells in attacking solid tumors.

17 Mar 2023

The impact of genome doubling on the development of cancer

Since a single cell has 2–3 m of DNA, the only method to store it is in tight coils. The answer is chromatin, a DNA-protein complex that is wrapped around histone proteins.

17 Mar 2023

Cell Biology News and Research

Latest Cell Biology News and Research

New study pinpoints key source of T cell "exhaustion"

T cell-driven changes in the gut may affect brain function associated with depression

Keeping lymph nodes in the body can boost the efficacy of cancer immunotherapy

Blunted inflammatory response could make obese patients more susceptible to severe COVID-19

Stickiness of influenza virus may determine the frequency of co-infection

DNA drugs help restore the normal processing of protein-encoding RNA

Macrophages likely to be a potential target for ER+ breast cancer

Perspectives on nucleolar DNA damage response in the fight against cancer

The protein synthesis mechanism in the Giardia parasite

Amide-to-ester substitutions can enhance the membrane permeability of cyclic hexapeptides

Study discovers the ability of certain blood immune cells to proliferate

Immune landscape in invasive ER+ breast cancers reveals a macrophage-driven microenvironment

Decreased viral infection severity in females linked to extra copy of epigenetic regulator

Delaying paralysis in ALS by using designer DNA drug

Neoadjuvant dual immunotherapy and chemotherapy improve outcomes in patients with resectable NSCLC

Using a programmable control switch to deliver therapeutic RNA molecules to target cells

Genomic analysis shows Ashaninka people are not as homogeneous as previously reported

Losing a productive type of beta cell may contribute to the development of diabetes

Potential approach to improve solid tumor T cell therapy

The impact of genome doubling on the development of cancer

Stem Cells eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Cell Biology News and Research

Latest Cell Biology News and Research

Stem Cells eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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