Cell Biology News and Research

Latest Cell Biology News and Research

Microbiotica Secures Approvals to Begin Clinical Studies in EU and UK for New Microbiome Medicines

Microbiotica, a biopharma company developing a pipeline of oral precision microbiome medicines called live biotherapeutic products (LBPs), is pleased to announce that it has received regulatory approvals to initiate clinical studies for its first two programmes in advanced melanoma (MELODY-1) and ulcerative colitis (COMPOSER-1) in selected EU countries and the UK. Both studies are due to start shortly, with initial data readouts expected by the end of 2025.

30 Aug 2024

RYBREVANT Receives EC Nod for Advanced Lung Cancer Treatment

Janssen-Cilag International NV, a Johnson & Johnson company, today announced that the European Commission (EC) has approved a Type II extension of indication for RYBREVANT®▼ (amivantamab) in combination with chemotherapy (carboplatin and pemetrexed), for the treatment of adults with advanced non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) Exon 19 deletions (ex19del) or Exon 21 L858R substitution (L858R) mutations, after failure of prior therapy including an EGFR tyrosine kinase inhibitor (TKI).

30 Aug 2024

Transforming Waste into Culinary Delights with Neurospora

Chef-turned-chemist Vayu Hill-Maini has a passion: to turn food waste into culinary treats using fungi.

30 Aug 2024

A Landmark Study Reveals the Widespread Existence of DNA i-Motifs

Innovative study of DNA's hidden structures may open up new approaches for treatment and diagnosis of diseases, including cancer.

30 Aug 2024

Bacterial Protein Utilizes DNA for Target Recognition and Plasmid Elimination

Scientists who have described in a new study the step-by-step details of a bacterial defense strategy see the mechanism as a promising platform for development of a new genome-editing method.

30 Aug 2024

Researchers on the Brink of a Scientific Breakthrough in Cancer Treatment

By figuring out how the body’s immune system targets diseased cells, a multinational team of scientists is on the cusp of a breakthrough in the fight against cancer.

29 Aug 2024

The Molecular Process That Causes MS and Autoimmune Diseases

A human immune system suppressor known as “regulatory T cells” was first identified more than 20 years ago by a research team working in the lab of Yale researcher David Hafler, who was at Harvard at the time.

29 Aug 2024

Study Reveals Unique DNA Replication Dynamics in Early Embryogenesis

Researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan have made a novel discovery that challenges long-held beliefs about DNA replication.

29 Aug 2024

Bifidobacterium in Maternal Gut Found to Alter Fetal Brain Growth

Bifidobacterium breve supplementation in pregnant mice alters fetal brain metabolism, highlighting its role in enhancing gestational health and development.

29 Aug 2024

High-Speed Atomic Force Microscopy Reveals Cofilin Binding Patterns in Actin Filaments

Researchers at Kanazawa University report in eLife on deciphering the actin structure-dependent preferential cooperative binding of cofilin.

29 Aug 2024

Single-Cell RNA Sequencing Reveals Cellular Changes in Early Alzheimer's Disease

An analysis of more than 1.6 million brain cells from older adults has captured the cellular changes that occur in the early stages of Alzheimer's disease, potentially revealing new routes for preventing the most common cause of dementia in older individuals.

29 Aug 2024

Illuminating Plant Defense Mechanisms Through Light-Activated Ion Channels

When it comes to survival, plants have a huge disadvantage compared to many other living organisms: they cannot simply change their location if predators or pathogens attack them or the environmental conditions change to their disadvantage.

29 Aug 2024

Bacterial Cells Pass on Non-Genetic Traits Across Generations

Bacterial cells can "remember" brief, temporary changes to their bodies and immediate surroundings, a new Northwestern University and University of Texas-Southwestern study has found.

29 Aug 2024

Sae2 Regulates Critical DNA Repair Functions in Yeast

DNA damage is a cellular phenomenon that introduces structural abnormalities in double-stranded DNA. External factors, such as radiation or chemical agents, as well as internal factors, such as blocked DNA replication, can generate double-strand breaks (DSBs) in DNA.

29 Aug 2024

The Influence of 'Silent' Mutations on Genetic Disorders

Genetic disorders -; like cystic fibrosis and Huntington's disease -; are considered incurable, with gene mutations occurring in essentially every cell of the body.

29 Aug 2024

New Map Reveals Hidden Interactions Between Receptors and Proteins

A single superfamily of receptors found on the surface of human cells is the target of one out of every three FDA-approved medications.

28 Aug 2024

Clock Genes Drive Evolutionary Split in Two Moth Species

Investigating moth speciation, this research highlights the impact of clock genes on behavior, providing a rare glimpse into evolutionary processes.

28 Aug 2024

Stem Cell Research Sheds Light on Rare Pediatric Condition

Scientists have identified mutations in the DENND5A gene that cause severe neurodevelopmental issues in infants, leading to improper brain cell division during development.

28 Aug 2024

RNA Interference Drugs Offer Faster, More Effective Alternative to Traditional Drug Discovery

Alnylam's RNA interference platform accelerates drug discovery by targeting RNA transcripts, addressing complex diseases with innovative therapeutic strategies.

28 Aug 2024

Cryo-EM Study Sheds Light on HSV Drug Resistance Mechanisms Through Protein Movement

All organisms -; from fungi to mammals -; have the capacity to evolve and adapt to their environments. But viruses are master shapeshifters with an ability to mutate greater than any other organism. As a result, they can evade treatments or acquire resistance to once-effective antiviral medications.

28 Aug 2024