Genetics and Genomics News and Research

Latest Genetics and Genomics News and Research

Research Reveals Regulatory Role of Glucose-6-Phosphate Dehydrogenase in Mitophagy

Mitophagy is a selective form of autophagy via which the damaged mitochondria are cleared via the autophagy-lysosome pathway.

30 Dec 2024

Scientists Develop Non-Destructive Method to Study Fish Teeth

Can we examine the teeth of living fish and other vertebrates in detail, repeatedly over time, without harming them?

27 Dec 2024

AI-Designed Nanocages Mimic Intricate Structures of Viruses

Professor Sangmin Lee from POSTECH's Department of Chemical Engineering, in collaboration with 2024 Nobel Chemistry Laureate Professor David Baker from the University of Washington, has developed an innovative therapeutic platform by mimicking the intricate structures of viruses using artificial intelligence (AI).

26 Dec 2024

New Platform Simplifies Protein-Protein Interaction Measurements

A team led by researchers at the University of Toronto has created a platform, called SIMPL2, that revolutionizes the study of protein-protein interactions by simplifying detection while improving measurement accuracy.

26 Dec 2024

New Study Reveals DNA’s Role in Stabilizing Cellular Structures

In a discovery that could redefine how we understand cellular resilience and adaptability, scientists at Scripps Research have unlocked the secret interactions between a primordial inorganic polymer of phosphate known as polyphosphate (polyP), and two basic building blocks of life: DNA and the element magnesium.

26 Dec 2024

Fruit Flies Evolve New Defense Through Gene Transfer

In the continual arms race between parasites and their hosts, innovation was thought to be the key to a successful attack or defense that one-ups the competition.

26 Dec 2024

New Gene Editing Tool Targets Alzheimer's by Skipping Disease-Causing Gene Segments

A new gene editing tool that helps cellular machinery skip parts of genes responsible for diseases has been applied to reduce the formation of amyloid-beta plaque precursors in a mouse model of Alzheimer's disease, researchers at the University of Illinois Urbana-Champaign report.

24 Dec 2024

Plant Research Reveals Unexpected Function for Key Cellular Protein

A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA – the first step of the process by which an organism's genetic code expresses itself. The fundamental breakthrough was discovered in apple cells but is relevant to all living organisms made of nucleus-containing cells, including humans.

24 Dec 2024

New Treatment Targets Tumor Microenvironment to Fight Breast Cancer

"Build your enemy a golden bridge to retreat across" is a piece of advice offered by Sun Tzu in his ancient military treatise, The Art of War. It turns out that cancerous growths adopt this strategy in their battle against the immune system.

24 Dec 2024

Digital Twin Technology Reverses Colon Cancer in Study by KAIST Researchers

Despite the development of numerous cancer treatment technologies, the common goal of current cancer therapies is to eliminate cancer cells. This approach, however, faces fundamental limitations, including cancer cells developing resistance and returning, as well as severe side effects from the destruction of healthy cells.

24 Dec 2024

New Synthetic Biology Tool Improves Genetic Circuit Integration and Functionality

The research team led by Professor Jongmin Kim from the Department of Life Sciences at POSTECH, along with graduate students Hyunseop Goh and Seungdo Choi, has successfully developed the 'Synthetic Translational Coupling Element (SynTCE),' significantly enhancing the precision and integration density of genetic circuits in synthetic biology.

23 Dec 2024

Discovery of ALAS1's Secret Role Could Boost Cancer Therapy Development

In everyday life, when things turn out the opposite of what you expect, it's usually cause for frustration. In science, it's often the starting point for discovery.

23 Dec 2024

PlantRNA-FM: Bridging the Gap Between RNA Structure and Function

With PlantRNA-FM, researchers can systematically analyze plant RNA, uncovering functional motifs that play key roles in gene expression and stress responses.

23 Dec 2024

New Genetic Link to Autism Identified

New research published in The American Journal of Human Genetics has identified a previously unknown genetic link to autism spectrum disorder (ASD). The study found that variants in the DDX53 gene contribute to ASD, providing new insights into the genetic underpinnings of the condition.

20 Dec 2024

New Insights into Pseudomonas syringae Toxin’s Impact on Non-Flowering Plants

The capacity of bacteria to spread disease across the Plant Kingdom may be much more widespread than previously suspected, according to new analysis.

20 Dec 2024

Engineering Yeast Promoters for Biologic Manufacturing

When introducing genes into yeast to make it produce drugs and other useful substances, it is also necessary to reliably switch the production on or off. A Kobe University team found three gene regulation design principles that provide a flexible guideline for the effective control of microbiological production.

19 Dec 2024

Neural Stem Cells Found to Rejuvenate the Aging Brain

Much like plants in a thriving forest, certain cells in the brain create a nurturing environment, enhancing the health and resilience of their neighbors, while others promote stress and damage, akin to a noxious weed in an ecosystem.

19 Dec 2024

Scientists Mimic Fungal Process to Create Novel Medicines

Since the unintentional 1928 discovery of penicillin by Alexander Fleming, fungi have been a treasure trove of medicinal compounds for almost a century.

19 Dec 2024

New Virus Found to Alter Cell Machinery in Eukaryotic Cells

Julie Thomy, lead author of the study and postdoctoral researcher in the Daniel K. Inouye Center for Microbial Oceanography: Research and Education (C-MORE) and Department of Oceanography in the UH Mānoa School of Ocean and Earth Science and Technology (SOEST)

18 Dec 2024

Space Experiment Reveals Surprising Brain Cell Behavior

Microgravity exposure accelerates brain cell development in organoids, revealing potential implications for neurodegenerative disease research and space health.

18 Dec 2024