Genetics and Genomics News and Research

Latest Genetics and Genomics News and Research

Hormone drugs may help disarm coronavirus spike protein and stop disease progression

Hormone drugs that reduce androgen levels may help disarm the coronavirus spike protein used to infect cells and stop the progression of severe COVID-19 disease, suggests a new preclinical study from researchers in the Abramson Cancer Center at the University of Pennsylvania and published online in Cell Press's iScience.

23 Mar 2021

Study reveals mechanism by which ibuprofen prevents RAC1B alternative splicing in colorectal cells

Oncotarget published "Ibuprofen disrupts a WNK1/GSK3β/SRPK1 protein complex required for expression of tumor-related splicing variant RAC1B in colorectal cells" which reported that although the molecular mechanism behind the antitumor properties of NSAIDs has been largely attributed to inhibition of cyclooxygenases , several studies have shown that the chemopreventive properties of ibuprofen also involve multiple COX-independent effects.

23 Mar 2021

“Hidden genetic defects” can cause a variety of illnesses in children

For the first time, scientists have gained a better understanding of the “hidden genetic defects” of the general population in Europe.

22 Mar 2021

New genetic engineering strategy largely reduces tau protein levels in Alzheimer’s animal model

A genetic engineering approach has helped scientists to drastically decrease the levels of tau protein.

22 Mar 2021

New technique based on AI can automate and streamline seed quality analysis

In Brazil, researchers affiliated with the Center for Nuclear Energy in Agriculture (CENA) and the Luiz de Queiroz College of Agriculture (ESALQ), both part of the University of São Paulo (USP), have developed a methodology based on artificial intelligence to automate and streamline seed quality analysis, a process required by law and currently done manually by analysts accredited with the Ministry of Agriculture.

22 Mar 2021

Low representation of minority groups in genomic databases may impact therapy selection

Low representation of minority groups in public genomic databases may affect therapy selection for Black patients with cancer, according to new Mayo Clinic research published in npj Precision Oncology.

22 Mar 2021

Study advances CAR T cell therapy targeted at cancer

Cancer immunotherapy involves the activation of cells in the patient’s own immune system to fight tumor cells.

19 Mar 2021

Rare genetic variants contribute to increased risk for lung cancer

In the United States, lung cancer is the main cause of cancer death in both male and female populations.

19 Mar 2021

Study identifies new biomarkers for the prognosis of gastric adenocarcinoma

A study headed by UCM reports that polymorphisms in gene TGFB1 and low plasma levels of protein TGFB1 serve as biomarkers for the gastric adenocarcinoma prognosis.

19 Mar 2021

New “genome scalpel” can rapidly trim microalgal genomes

A single-celled alga removes non-essential pieces by undergoing genome surgery.

18 Mar 2021

Immune receptor proteins can help treat autoimmune diseases

TARM1 is a receptor protein, whose function in the working of the immune system is not known yet. Now, in a new research work, Japanese researchers have analyzed mouse models to investigate the promising role of TARM1 protein in the pathogenesis of rheumatoid arthritis.

From Tokyo University of Science 18 Mar 2021

Study shows beneficial effects of gene therapy can be observed even after several decades

A new study shows that the advantageous effects of gene therapy can be observed several decades after the body clears the transplanted blood stem cells.

From University College London 18 Mar 2021

Study provides clues for designing more effective antiviral drugs

An international research team from the University of Turku based in Finland and PennState University based in the United States has solved an ancient puzzle of how living organisms differentiate between DNA and RNA building blocks at the time of gene expression, offering new possibilities for designing novel antiviral medications.

18 Mar 2021

New highly sensitive RNA detection method advances in situ transcriptomics

Human cells typically transcribe half of their roughly 20,000 genes into RNA molecules at any given time. Just like with proteins, the function of those RNA species not only relies on their abundance but also their precise localization within the 3D space of each cell.

18 Mar 2021

Mitigating the negative impacts of artificial light at night on wildlife

Artificial light at night (ALAN) is a major factor in global insect decline. In a paper published today in Insect Conservation and Diversity, Smithsonian Conservation Biology Institute (SCBI) scientists and partners found that using amber-colored filters to remove the blue spectra of light from "warm white" LED (light-emitting diode) lamps drastically reduces insect attraction to nocturnal lighting in a tropical forest.

18 Mar 2021

Scientists find a better way to identify cells and understand disease mechanisms

In researching the causes and potential treatments for degenerative conditions such as Alzheimer's or Parkinson's disease, neuroscientists frequently struggle to accurately identify cells needed to understand brain activity that gives rise to behavior changes such as declining memory or impaired balance and tremors.

18 Mar 2021

Researchers identify address codes in odorant receptor proteins for the first time

A team of scientists led by Dietmar Krautwurst from the Leibniz Institute for Food Systems Biology at the Technical University of Munich has now identified address codes in odorant receptor proteins for the first time.

18 Mar 2021

Scientists provide a complete phenotypic landscape of SCN2A-related disorders

Researchers from Children's Hospital of Philadelphia (CHOP) affiliated with the CHOP Epilepsy Neurogenetics Initiative (ENGIN) have compiled a complete genetic and clinical analysis of more than 400 individuals with SCN2A-related disorder, which has been linked to a variety of neurodevelopmental disorders, including epilepsy and autism.

18 Mar 2021

$1 million NSF grant effort to explore a natural process that saps plants' productivity

Plants were evolving for hundreds of millions of years before humans started cultivating them for food. So when the first farmers showed up some 12,000 years ago, plants had already picked up some inefficiencies -- that is, adaptations that helped the plants survive but also limited their productivity as crops.

17 Mar 2021

Decades of crop breeding prevents modern corn from recruiting nitrogen-fixing microbes

Corn didn't start out as the powerhouse crop it is today. No, for most of the thousands of years it was undergoing domestication and improvement, corn grew humbly within the limits of what the environment and smallholder farmers could provide.

17 Mar 2021

Genetics and Genomics News and Research

Latest Genetics and Genomics News and Research

Hormone drugs may help disarm coronavirus spike protein and stop disease progression

Study reveals mechanism by which ibuprofen prevents RAC1B alternative splicing in colorectal cells

“Hidden genetic defects” can cause a variety of illnesses in children

New genetic engineering strategy largely reduces tau protein levels in Alzheimer’s animal model

New technique based on AI can automate and streamline seed quality analysis

Low representation of minority groups in genomic databases may impact therapy selection

Study advances CAR T cell therapy targeted at cancer

Rare genetic variants contribute to increased risk for lung cancer

Study identifies new biomarkers for the prognosis of gastric adenocarcinoma

New “genome scalpel” can rapidly trim microalgal genomes

Immune receptor proteins can help treat autoimmune diseases

Study shows beneficial effects of gene therapy can be observed even after several decades

Study provides clues for designing more effective antiviral drugs

New highly sensitive RNA detection method advances in situ transcriptomics

Mitigating the negative impacts of artificial light at night on wildlife

Scientists find a better way to identify cells and understand disease mechanisms

Researchers identify address codes in odorant receptor proteins for the first time

Scientists provide a complete phenotypic landscape of SCN2A-related disorders

$1 million NSF grant effort to explore a natural process that saps plants' productivity

Decades of crop breeding prevents modern corn from recruiting nitrogen-fixing microbes

Genetics & Genomics - Second Edition eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

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Genetics and Genomics News and Research

Latest Genetics and Genomics News and Research

Genetics & Genomics - Second Edition eBook

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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