Genetics and Genomics News and Research

Latest Genetics and Genomics News and Research

Study reports first-ever application of CRISPR-Cas12b system in plant genome engineering

Study reports first-ever application of CRISPR-Cas12b system in plant genome engineering

In a study reported recently in Nature Plants, Yiping Qi—assistant professor of Plant Science at the University of Maryland—has found a new CRISPR genome engineering system, called CRISPR-Cas12b, that is viable in plants for the first time.

10 Mar 2020

Study explores the impact of solute carriers on the activity and potency of cytotoxic drugs

Study explores the impact of solute carriers on the activity and potency of cytotoxic drugs

At the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, scientists have investigated how solute carriers (SLCs)—a large class of membrane transport proteins—affect the activity and potency of cytotoxic drugs, for example, those used to treat leukemia and other cancers.

10 Mar 2020

New study on viruses could help design engineered nano-shells used in drug delivery

New study on viruses could help design engineered nano-shells used in drug delivery

Viruses are small disease-causing parasites with the potential to infect all life forms. Although they have been analyzed well, there still exist several mysteries.

10 Mar 2020

New chromosome-level detectors developed to monitor cellular activity

New chromosome-level detectors developed to monitor cellular activity

For researchers investigating the regulatory processes in cells that are vital to all life, an innovative system that amplifies gene expression signals could be a turning point.

10 Mar 2020

Statistics used to find how genetics influence coffee intake

Statistics used to find how genetics influence coffee intake

Some people feel like drinking three cups of coffee in a day while others feel content with just one cup, and some others give up entirely. Why is it so?

9 Mar 2020

Nucleosomal DNA Dynamics Mediate Oct4 Pioneer Factor Binding

Nucleosomal DNA Dynamics Mediate Oct4 Pioneer Factor Binding

An international team of researchers has disproved the role of an essential protein, known as Oct4, in regulating gene expression.

22 Feb 2020

WDR74 modulates melanoma tumorigenesis and metastasis through the RPL5–MDM2–p53 pathway

WDR74 modulates melanoma tumorigenesis and metastasis through the RPL5–MDM2–p53 pathway

A team of scientists has discovered that the WDR74 protein plays a vital role in metastasis progression in lung cancer and melanoma primary tumors.

22 Feb 2020

New correlative, 3D, super resolution imaging platform reveals unexpected findings in mammalian cells

New correlative, 3D, super resolution imaging platform reveals unexpected findings in mammalian cells

Researchers have developed a platform for the 3D super-resolution imaging at the nanoscale level that has revealed unexpected findings in mammalian cells.

21 Feb 2020

Distinct loss-of-function variants cause shared clinical features in neuronal development disorders

Distinct loss-of-function variants cause shared clinical features in neuronal development disorders

Researchers have shown that mutations in four distinct genes that lead to Kleefstra syndrome.

20 Feb 2020

New single-cell isolation method could revolutionize live cell imaging

New single-cell isolation method could revolutionize live cell imaging

Researchers have proposed a new high-throughput, multigenerational time-lapse imaging platform, capable of single-cell screening.

20 Feb 2020

Understanding bipolar disorder and its potential future developments

Understanding bipolar disorder and its potential future developments

Bipolar disorder is estimated to affect around 1 to 4% of the population, but understanding the underlying genetics has proved a major challenge.

15 Feb 2020

Examining the genetics of cortical myelination in young adults using MRI

Examining the genetics of cortical myelination in young adults using MRI

The cerebrum is the largest part of the human brain, accounting for about two-thirds of its overall weight.

14 Feb 2020

Considering evolution of the cancer genome in metastatic disease

Considering evolution of the cancer genome in metastatic disease

Metastasis refers to the spread of cancer cells from primary tumors to distant sites that they then colonize to form a metastatic tumor.

13 Feb 2020

A new study finds a potential immunotherapeutic pan-target on cancer cells

A new study finds a potential immunotherapeutic pan-target on cancer cells

In a genome-wide CRISPR-Cas9 screen published in Nature Immunology in January 2020, a group of researchers described a potential universal target on cancer cells.

12 Feb 2020

Clinical lipidomics in understanding of lung cancer: Opportunity and challenge

Clinical lipidomics in understanding of lung cancer: Opportunity and challenge

A team of scientists has recently outlined the need to develop and standardize lipidomic measurements and baseline figures.

11 Feb 2020

An analysis of the effects GM crops have on agriculture

An analysis of the effects GM crops have on agriculture

Genetic modification (GM) of crops refers to the insertion of a DNA sequence (transgene) into a plant’s genome to confer new characteristics.

8 Feb 2020

Genetic variation in taste receptors could help inform food production

Genetic variation in taste receptors could help inform food production

Taste is a key factor in determining which food and drink items consumers buy.

7 Feb 2020

“Cellular agriculture” could address sustainability challenges in the manufacture of foods

“Cellular agriculture” could address sustainability challenges in the manufacture of foods

Conventional agricultural food production methods currently seem unlikely to be able to provide for the food requirements of the world’s increasing population.

6 Feb 2020

Potential biomarker for lung cancer prognosis revealed

Potential biomarker for lung cancer prognosis revealed

A recent study has revealed that the expression of long noncoding RNA LINC00426 is related to prognosis for non‐small cell lung cancer.

3 Feb 2020

Circular RNA profiles could serve as a biomarker of ovarian cancer

Circular RNA profiles could serve as a biomarker of ovarian cancer

A team has revealed the existence of viable biomarkers of ovarian cancer by investigating the profiles of circular RNA expression.

3 Feb 2020

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