Lab Automation and Bioinformatics News and Research

Latest Lab Automation and Bioinformatics News and Research

TRISCO Reveals 3D RNA Structures at Cellular Resolution

A novel microscopy technique created by researchers at the Karolinska Institutet and Karolinska University Hospital allows for in-depth, three-dimensional (3D) RNA analysis at the cellular level in complete, undamaged mouse brains.

22 Nov 2024

Immunotherapy Advances: CAR T Cells Targeting GD2 Offer Hope for Glioma Patients

Findings suggest GD2-specific CAR T-cell therapy is a viable option for H3K27M-mutant gliomas, with significant tumor shrinkage and clinical benefits observed.

22 Nov 2024

Scientists Map Microbiome of Rivers Across the U.S.

Rivers and streams serve as critical connectors across vast geographical landscapes, trickling out of tucked-away headwaters and snaking thousands of miles toward oceans and deep seas.

21 Nov 2024

Discovery of Large Tandem Duplications Opens New Avenues for Cancer Treatment

Cancer researchers at the University of Chicago and the University of California, San Francisco (UCSF) have discovered that mutations in certain genes can lead to the accumulation of DNA errors, resulting in a specific type of genetic change known as large tandem duplications (TDs) that can arise from the collision of two critical cellular processes: transcription and DNA replication.

21 Nov 2024

Scientists Use Cell Density to Control Tissue Formation

Genes aren't the sole driver instructing cells to build multicellular structures, tissues, and organs.

20 Nov 2024

Advanced Sequencing Uncovers Cause of Rare Mitochondrial Encephalopathy

Mitochondrial diseases are among the most prevalent hereditary metabolic disorders, known to occur in one out every 5000 births.

19 Nov 2024

Understanding Marine Worms’ Unique Ability to Regenerate Lost Body Parts

Many living organisms are able to regenerate damaged or lost tissue, but why some are particularly good at this and others are not is not fully understood.

19 Nov 2024

Study Reveals Key Role of Interleukin-38 in Skin Renewal

The mechanisms underlying skin renewal are still poorly understood. Interleukin-38 (IL-38), a protein involved in regulating inflammatory responses, could be a game changer.

19 Nov 2024

Study Reveals Key Role of Viscoelasticity in Cellular Response to Mechanical Signals

A study by CNIC, published in Science Advances, offers a new approach to understanding how cells respond to mechanical signals from their environment, redefining the comprehension of the relationship between cells and their physical surroundings.

18 Nov 2024

Magnesium-Focused Approach to Curbing Antibiotic Resistance

According to recent estimates, the number of fatal antibiotic-resistant illnesses is expected to increase significantly over the next 25 years.

18 Nov 2024

New Study Compares MALDI-TOF MS Assays for Detecting Carbapenemase Activity

Austrian researchers evaluate MALDI-TOF MS assays for carbapenemase detection, assessing their reliability and practicality in managing resistant infections.

18 Nov 2024

Scientists Capture Viral Infection Process Using Light Microscope

The COVID-19 pandemic led to heightened public interest in learning about viruses and how they can cause diseases.

15 Nov 2024

Unveiling the Clinical Significance of Microbial Load in Human Health

Scientists built a new machine-learning model to predict microbial load — the density of microorganisms in the guts — and used it to explain how microbial load plays an essential role in disease-microbiome relationships.

14 Nov 2024

Integrative Taxonomy Uncovers Cryptic Daisy Species

Sometimes plants are sufficiently similar to one another that the procedures used by 18th-century scientist Carl Linnaeus for distinguishing species are insufficient.

14 Nov 2024

Researchers Provide Genetic Diagnosis for 30 Long-Term Undiagnosed Cases

An international team of researchers has provided a genetic diagnosis for 30 individuals whose condition was undiagnosed for years despite extensive clinical or genetic testing.

11 Nov 2024

Using Machine Learning to Understand Gene Interactions

By examining changes in gene expression, researchers gain insights into how cells operate at a molecular level, which can contribute to a better understanding of the onset of various diseases.

8 Nov 2024

CRISPR Reveals Hidden Functions of Noncoding RNA

Genes contain instructions for protein production, with the central dogma of biology stating that this information flows from DNA to RNA to proteins.

8 Nov 2024

New GIFT Method Outshines GWAS in Genetic Breakthrough

Genomic Informational Field Theory (GIFT) enhances genetic association detection, outperforming GWAS in mapping complex traits and subtle genetic interactions.

8 Nov 2024

New Understanding of the Evolution of Multicellular Life

In 2017, the single-celled species Chromosphaera perkinsii was found in maritime sediments in Hawaii. More than a billion years ago, long before the first animals appeared on Earth, the earliest indications of its existence were found.

7 Nov 2024

Study Reveals How Plants Override Genetic Instructions Through DNA Duplication

Biologists at Washington University in St. Louis have discovered the origin of a curious duplication that gives plants multiple ways to override instructions that are coded into their DNA.

7 Nov 2024