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Yourgene Health Becomes a PacBio Compatible Partner: Enabling PacBio Customers to Optimise Size Selection for Long-Read Sequencing Libraries

Yourgene Health (part of the Novacyt group of companies), a leading international molecular diagnostics group, and PacBio, a leading developer of high-quality, highly accurate sequencing solutions, today announced a collaboration to optimise size selection for long-read sequencing workflows.

From PacBio 20 Nov 2023

Scientists Discover New Class of Molecular Glue Degraders for Cancer Therapy

Cells contain molecular machinery that targets and disposes of unwanted proteins to maintain homeostasis.

17 Nov 2023

Gene Splicing Affects CD20 Expression and Response to Cancer Immunotherapy

Immunotherapies that target the CD20 antigen have revolutionized how patients with a variety of blood cancers and hematologic disorders have been treated.

17 Nov 2023

Study Uncovers Ancestry-Specific Genetic Factors in IBD

The advent of whole genome sequencing technology has prompted an explosion in research into how genetics are associated with disease risk.

17 Nov 2023

New Model Reveals How Cells Maintain Epigenetic Memory During Cell Division

Every cell in the human body contains the same genetic instructions, encoded in its DNA. However, out of about 30,000 genes, each cell expresses only those genes that it needs to become a nerve cell, immune cell, or any of the other hundreds of cell types in the body.

17 Nov 2023

Novel Biosensors Uncover Brain Activity

Researchers have employed novel biosensors to uncover neuropeptide activity in the brain, introducing innovative tools for examining the release, function, and regulation of these vital signaling molecules in vivo.

17 Nov 2023

Wilmot Researchers Uncover a "Genomic Tug of War" That Influences Decitabine's Effectiveness

Some patients with myelodysplastic syndromes, like acute myeloid leukemia, benefit from a chemotherapy drug called decitabine that stunts cancer growth. But many others are resistant to decatibine's effects or become resistant over time.

17 Nov 2023

Cycads and Dinosaurs: A Symbiotic Tale Unearthed

A recent study performed reveals that the surviving cycad species owe their persistence to symbiotic bacteria in their roots.

17 Nov 2023

The Link Between Tumor Cell Mutations and DNA-RNA Hybrids

New research indicates that chromatin and its regulatory factors play a crucial role in preventing the formation of DNA-RNA hybrids, which are linked to genomic instability and cancer.

17 Nov 2023

Unraveling the Mystery of L-Cry: A Distinctive Cryptochrome Protein

In a recent release in Nature Communications, a collaborative research group comprising Johannes Gutenberg University Mainz (JGU), the University of Cologne, and the University of Oldenburg has disclosed their discoveries regarding the operation of a distinctive cryptochrome protein (Cry).

16 Nov 2023

A Surprising Control Mechanism of Chlamydomonas Cell Division

Headed by James Umen, PhD, a team of international researchers at the Donald Danforth Plant Science Center has uncovered a surprising revelation about the single-celled green alga Chlamydomonas and its control over cell division.

16 Nov 2023

Understanding Phytoplankton Dynamics in Qinghai Lake

The rampant proliferation of filamentous algae has emerged as a worldwide issue, presenting significant obstacles to the effective control of prominent water reservoirs, such as Qinghai Lake in China, the largest lake on the Qinghai-Tibet plateau.

16 Nov 2023

Dinosaur Reproductive Strategies Uncovered Through Fossil Analysis

The last three decades have witnessed the discovery of several remarkably well-preserved dinosaur specimens related to reproduction, significantly advancing the understanding of dinosaur reproductive biology.

16 Nov 2023

More Genes Changed By Early Life Stress Than Head Injury

Researchers recently discovered a phenomenon as they delved into the investigation of whether early-life stress exacerbates the impact of a childhood head injury on health and behavior in later years.

16 Nov 2023

Tokyo Metropolitan University Decodes DNA Repair Mechanisms

Tokyo Metropolitan University researchers have uncovered crucial aspects of the DNA repair mechanism within human bodies.

16 Nov 2023

Northwestern University’s Deep Dive into Yucatán’s Underwater Labyrinth

Assisted by an adept underwater cave-diving team, scientists from Northwestern University have meticulously charted the most comprehensive map to date of microbial communities inhabiting the submerged mazes beneath Mexico’s Yucatán Peninsula.

16 Nov 2023

Revolutionizing Live Cell Imaging: Dye-Based Techniques for Rapid, Clear Insights

Researchers from CÚRAM at the University of Galway, in collaboration with their counterparts at the Centre for Molecular Nanometrology at the University of Strathclyde, have released findings that reveal the intricate mechanisms within cells.

16 Nov 2023

Novel Modeling Approach can Predict Dynamics and Functions of Microbial Communities

Microbial communities, or microbiomes, are essential for safeguarding human and environmental health through the most widely used biotechnological process on our planet: biological wastewater treatment.

15 Nov 2023

Circular Extrachromosomal DNA Linked to Medulloblastoma Relapse and Death

A study of newly created databases of medulloblastoma has found that patients with tumors containing circular extrachromosomal DNA-;loops of DNA found outside of regular chromosomes-;are twice as likely to relapse and three times as likely to die within five years of diagnosis.

15 Nov 2023