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Discovering the Critical Role of Astrocytes in Neurodegenerative Diseases

AZoLifeSciences talks to Dr. Shane Liddelow about their research into discovering the critical role of astrocytes in neurodegenerative diseases like glaucoma.

From New York University (NYU) 29 Jul 2020

Research into metal-breathing bacteria could pave way for new generation of 'living sensors'

When the Shewanella oneidensis bacterium "breathes" in certain metal and sulfur compounds anaerobically, the way an aerobic organism would process oxygen, it produces materials that could be used to enhance electronics, electrochemical energy storage, and drug-delivery devices.

29 Jul 2020

Scientists map the genome of aphid-like pest that decimates vineyards

Following a decade-long effort, scientists have mapped out the genome of an aphid-like pest capable of decimating vineyards. In so doing, they have discovered how it spreads -- and potentially how to stop it.

29 Jul 2020

Deep learning algorithm can infer molecular alterations in cancer from histology images

Researchers at the University of Chicago Medicine Comprehensive Cancer Center, working with colleagues in Europe, created a deep learning algorithm that can infer molecular alterations directly from routine histology images across multiple common tumor types.

29 Jul 2020

Biologists identify a molecular mechanism that underlies phenotypic plasticity

Evolutionary and developmental biologist Craig Albertson and colleagues at the University of Massachusetts Amherst report that they have identified a molecular mechanism that allows an organism to change the way it looks depending on the environment it is exposed to, a process known as phenotypic plasticity.

29 Jul 2020

Scientists discover evolutionary lineage of SARS-CoV-2 virus

By reconstructing the evolutionary history of SARS-CoV-2, the virus that is responsible for the COVID-19 pandemic, an international research team of Chinese, European and U.S. scientists has discovered that the lineage that gave rise to the virus has been circulating in bats for decades and likely includes other viruses with the ability to infect humans.

29 Jul 2020

Researchers uncover a novel mechanism by which cancer cells adapt to stress

Collaborative Cancer Research UK-funded studies from University of Oxford researchers have uncovered a new mechanism by which cancer cells adapt to the stresses they encounter as they grow and respond to therapies.

29 Jul 2020

Human genome may explain the neonatal origins of immune and inflammatory diseases

A study published in the journal Nature Communications has pinpointed a number of areas of the human genome that may help explain the neonatal origins of chronic immune and inflammatory diseases of later life, including type 1 diabetes, rheumatoid arthritis and coeliac disease.

29 Jul 2020

Study sheds new light on core regulatory networks that govern cell types in vertebrates

The FANTOM Consortium has shed new light into the main regulatory networks that govern the types of cells found in different vertebrate species.

29 Jul 2020

New technology helps visualize entire genome at molecular resolution

Scientists from Harvard University, CNAG, and CRG have demonstrated a pioneering technology that helps observe hundreds of genomes under the microscope.

29 Jul 2020

Study pinpoints the miRNA that promotes hair follicle growth

A research team from North Carolina State University has discovered a microRNA, or miRNA, that could make hairs to grow again.

29 Jul 2020

Testing COVID-19 with FDA-approved drugs can improve outcomes for affected patients

A protein found in viruses that are responsible for causing SARS and COVID-19 infections is virtually identical.

29 Jul 2020

AI algorithm can identify patterns of mutations and prognosis from tumor images

Researchers at EMBL's European Bioinformatics Institute, the Wellcome Sanger Institute, Addenbrooke's Hospital in Cambridge, UK, and collaborators have developed an artificial intelligence algorithm that uses computer vision to analyse tissue samples from cancer patients.

28 Jul 2020

Researchers identify how airway cells work together in regeneration and aging

Researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have identified the process by which stem cells in the airways of the lungs switch between two distinct phases -- creating more of themselves and producing mature airway cells -- to regenerate lung tissue after an injury.

28 Jul 2020

Highly invasive tumor cells have 'longer' finger-like projections

Tiny finger-like projections called filopodia drive invasive behavior in a rare subset of lung cancer cells, researchers at Winship Cancer Institute of Emory University have found.

28 Jul 2020

A novel approach to identify cancer targets using 'synthetic lethality'

With advances in genome sequencing, cancer treatments have increasingly sought to leverage the idea of "synthetic lethality," exploiting cancer-specific genetic defects to identify targets that are uniquely essential to the survival of cancer cells.

28 Jul 2020

Virginia Tech scientists reveal molecular cause underlying rare genetic disorder

Virginia Tech scientists have revealed how a nonfunctioning version of an ordinary gene impairs brain structure and function. The findings help explain a genetic form of microcephaly -- a condition where babies' heads are small and grow more slowly than their peers.

28 Jul 2020

Community-based genetic screening has potential to identify individuals at risk for inherited diseases

In a new study published today in the journal Nature Medicine, researchers behind the Healthy Nevada Project® suggest that community-based genetic screening has the potential to efficiently identify individuals who may be at increased risk for three common inherited genetic conditions known to cause several forms of cancer and increased risk for heart disease or stroke.

28 Jul 2020

Novel label-free imaging method can differentiate between quiescent and activated T cells

T cells are the immune soldiers at the frontlines of the battle with infiltrating pathogens that seek to cause disease. A new study published in Nature Biomedical Engineering describes a novel label-free imaging technique that can differentiate active T cells from those off duty.

28 Jul 2020

EBV viral genome modifies the host epigenetic landscape to promote gastric cancer

The Epstein-Barr virus (EBV), one of the most common human viruses, is associated with about 8-10 per cent of stomach -- or gastric -- cancers, the third leading cause of cancer death globally.

28 Jul 2020

Life Science News

Discovering the Critical Role of Astrocytes in Neurodegenerative Diseases

Research into metal-breathing bacteria could pave way for new generation of 'living sensors'

Scientists map the genome of aphid-like pest that decimates vineyards

Deep learning algorithm can infer molecular alterations in cancer from histology images

Biologists identify a molecular mechanism that underlies phenotypic plasticity

Scientists discover evolutionary lineage of SARS-CoV-2 virus

Researchers uncover a novel mechanism by which cancer cells adapt to stress

Human genome may explain the neonatal origins of immune and inflammatory diseases

Study sheds new light on core regulatory networks that govern cell types in vertebrates

New technology helps visualize entire genome at molecular resolution

Study pinpoints the miRNA that promotes hair follicle growth

Testing COVID-19 with FDA-approved drugs can improve outcomes for affected patients

AI algorithm can identify patterns of mutations and prognosis from tumor images

Researchers identify how airway cells work together in regeneration and aging

Highly invasive tumor cells have 'longer' finger-like projections

A novel approach to identify cancer targets using 'synthetic lethality'

Virginia Tech scientists reveal molecular cause underlying rare genetic disorder

Community-based genetic screening has potential to identify individuals at risk for inherited diseases

Novel label-free imaging method can differentiate between quiescent and activated T cells

EBV viral genome modifies the host epigenetic landscape to promote gastric cancer

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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