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Mechanical Manipulation of Stem Cells Promises New Treatments

New stem cell therapies may result from a novel method that McGill researchers have created for mechanically modifying stem cells, which has not yet reached its full therapeutic potential.

14 Aug 2024

Lipid Accumulation Linked to Senescence in Dopaminergic Neurons

A new research perspective was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 14 on July 19, 2024, entitled, "Lipid accumulation drives cellular senescence in dopaminergic neurons."

14 Aug 2024

Study Reveals Mechanisms Behind Lineage Restriction in Cell Development

A team of researchers from multiple institutions including the University of Chicago and VectorBuilder, has made a significant breakthrough in the understanding of lineage restriction, a biological phenomenon foundational to multicellular lifeforms as it secures the functional identities of the myriad cell types in the body.

14 Aug 2024

IU Scientists Map Breast Cells to Explore Cancer Origins and Genetic Ancestry Impact

Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have completed the most extensive mapping of healthy breast cells to date.

14 Aug 2024

Driving Support for Pharmaceutical Testing Through Continuous Innovation

In this interview, Kyle James from ERWEKA highlights the company's commitment to supporting pharmaceutical sciences through advanced equipment and continuous innovation.

From ERWEKA 14 Aug 2024

Deep-Learning Model Identifies Parkinson's Disease-Specific Neuroanatomical Features

A deep-learning-based contrastive approach to examine magnetic resonance imaging (MRI) scans from Parkinson’s disease patients.

14 Aug 2024

Brain's Co-Rippling Activity Sheds Light on Consciousness

For many years, researchers have been concentrating on how the brain organizes information into hierarchical structures, with distinct regions of the brain designated for distinct functions.

13 Aug 2024

New Breast Cell Atlas Enhances Understanding of Cancer Origins

Scientists at the Melvin and Bren Simon Comprehensive Cancer Center at Indiana University have finished the largest mapping of healthy breast cells to date.

13 Aug 2024

Novel Technique to Study Ubiquitination

Once human proteins are synthesized, they go through some chemical changes. These adjustments control their stability, functionality, and structure.

13 Aug 2024

Light-Activated Macrophages Show Increased Appetite for Cancer Cells

The body has a veritable army constantly on guard to keep us safe from microscopic threats from infections to cancer.

13 Aug 2024

New Insights into How Cell Nuclei Shape Tissue Architecture During Development

In work conducted both at UC Santa Barbara and the Physics of Life Excellence Cluster of TU Dresden, biophysicist Otger Campàs and his research group have found that cell nuclei control the architecture and mechanics of eye and brain tissues during embryonic development.

13 Aug 2024

Discovery of Efficient Glycosyltransferases for Pterocarpan Glycoside Biosynthesis

A research team has identified two highly efficient glycosyltransferases, AmGT28 and AmGT44, from Astragalus membranaceus, which convert medicarpin to medicarpin 3-O-glucoside and show a preference for pterocarpans over isoflavonoids.

13 Aug 2024

Advancing Genome Visualization with CRISPR/Cas9 Technology in Live Cells

Understanding the spatiotemporal organization of the genome in the nucleus is crucial for advancing our knowledge of chromatin structure and its functional dynamics in both normal and diseased states.

13 Aug 2024

New AI Model Predicts Protein-DNA Binding Specificity with High Accuracy

A new artificial intelligence model developed by USC researchers and published in Nature Methods can predict how different proteins may bind to DNA with accuracy across different types of protein, a technological advance that promises to reduce the time required to develop new drugs and other medical treatments.

12 Aug 2024

Scientists Discover a New Mechanism for Epithelial Tissue Development

How three-dimensional tissue forms emerge during animal development is one of the fundamental questions in biology and biophysics that remains unanswered.

12 Aug 2024

A Breakthrough in the Synthesis of Potent Bioactive Molecules

There are many chemical compounds with amazing medical capabilities found in the natural world. One famous example is penicillin, which was unintentionally found in the Penicillium mold. This discovery demonstrated the potential of natural substances in medicine and transformed the treatment of bacterial illnesses.

12 Aug 2024

Microbes Shape the Taste of France's PDO Cheeses

Around 46 regional cheeses in France are designated as having protected designation of origin (PDO) status. The terroirs, or diverse regional landscapes, of France influence the microbiological diversity of PDO cheeses, creating their distinct flavors.

12 Aug 2024