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Cells Harvested From Urine May Have Diagnostic Potential for Kidney Disease

Genes expressed in human cells harvested from urine are remarkably similar to those of the kidney itself, suggesting they could be an important non-invasive source of information on the kidney.

20 Mar 2024

New Biomarker Offers Early Detection of ALS and FTD

Two progressively degenerative diseases, amyotrophic lateral sclerosis (ALS, commonly known as Lou Gehrig's disease) and frontotemporal dementia (FTD, recently in the news with the diagnoses of actor Bruce Willis and talk show host Wendy Williams), are linked by more than the fact that they both damage nerve cells critical to normal functioning -; the former affecting nerves in the brain and spinal cord leading to loss of movement, the latter eroding the brain regions controlling personality, behavior and language.

19 Mar 2024

Machine Learning Reveals Cancer-Causing DNA Repeats

It has been difficult to identify and characterize repeats of DNA sequences, also known as “junk DNA” or “dark matter,” that are found in chromosomes and may be involved in cancer or other diseases.

14 Mar 2024

Scientists Design Proteins to Reach Hidden Cellular Targets

Drug developers have long faced challenges in reaching targets embedded within the cell membrane because of the membrane's complex biochemical properties. Chemists at Scripps Research have now shown that novel, specially made proteins are capable of effectively reaching these “intramembrane” targets.

14 Mar 2024

Breakthrough: Transgenic Cow Produces Human Insulin in Milk

An unassuming brown bovine from the south of Brazil has made history as the first transgenic cow capable of producing human insulin in her milk.

14 Mar 2024

Dual-Target CAR T Cell Therapy Shows Promise Against Recurrent Glioblastoma

Targeting two brain tumor-associated proteins-;rather than one-;with CAR T cell therapy shows promise as a strategy for reducing solid tumor growth in patients with recurrent glioblastoma (GBM), an aggressive form of brain cancer, according to early results from the first six patients treated in an ongoing Phase I clinical trial led by researchers from the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine's Abramson Cancer Center.

14 Mar 2024

Study Reveals Key Role of STAP-1 in Immune Function

A recent study has illuminated the significance of the protein STAP-1 in activating specific immune cells.

13 Mar 2024

Study Reveals Unique Bacterial Fingerprints and Their Impact on Health

The trillions of bacteria that call your body home -; collectively known as the microbiome -; appear to be unique to you, like a fingerprint.

13 Mar 2024

Biological Glue Provides Clues About Cardiovascular Diseases

University of Virginia School of Medicine scientists have found important answers about strokes, heart attacks and cardiovascular diseases by probing the biological glue our bodies create to protect us from those deadly dangers.

12 Mar 2024

The Role of Vitamin A in the Pathogenesis of Psychiatric Disorders

A group of researchers in Newcastle has been investigating the part that vitamin A plays in the pathogenesis of psychiatric disorders.

12 Mar 2024

Study Reveals STAP-1 Protein's Role in Immune Disorders

A new study highlights a potential therapeutic target for immune-related disorders, such as multiple sclerosis and asthma.

12 Mar 2024

Reducing Iron May Reverse Stem Cell Aging

It is fascinating to learn how researchers at the Albert Einstein College of Medicine and the National Cancer Institute-designated Montefiore Einstein Comprehensive Cancer Center (MECCC) have discovered a way to prevent or even reverse the function of hematopoietic (blood-forming) stem cells (HSCs) as they age.

11 Mar 2024

Blood-Based Markers Unveil Secrets of Biological Aging

University of Pittsburgh researchers have uncovered blood-based markers linked with healthy and rapid aging, allowing them to predict a person's biological age -; how fast a person's cells and organs age regardless of their birthdate.

11 Mar 2024

Eight Voices of Progress: AZoNetwork #InspiresInclusion for International Women's Day 2024

Each year on March 8th, International Women's Day (IWD) shines a spotlight on the monumental achievements of women around the globe. For 2024, the theme #InspireInclusion invites us to embrace diversity and champion the inclusion of women in all spheres of life.

8 Mar 2024

Strategies to Counter Postnatal Growth Retardation in Piglets

The metabolic basis of postnatal growth retardation (PGR) in piglets is not yet clear, but it is characterized by poor production performance, low feed conversion rate, and a high mortality rate.

4 Mar 2024

SOX17 Gene Identified as Critical for Immune Evasion in Early-Stage Colon Cancer

One of the immune system's primary roles is to detect and kill cells that have acquired cancerous mutations.

29 Feb 2024

New "Tissue-in-a-CUBE" Offers Alternative to Animal Testing in Drug Development

A research team at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan has succeeded in establishing a model of the blood-brain barrier using modularized tissue derived from human cells.

29 Feb 2024

UMass Amherst Study Shows Promise in Retraining Immune Cells for Targeting Aplastic Anemia

Researchers at the University of Massachusetts Amherst recently released a first-of-its-kind study that focuses on the rare autoimmune disorder aplastic anemia to understand how a subset of cells might be trained to correct the overzealous immune response that can lead to fatal autoimmune disorders.

28 Feb 2024

Tandem Repeat Expansions Linked to Cardiomyopathy Risk, Reveals Study

In the first study to use whole genome sequencing to examine tandem repeat expansions in heart conditions, scientists at The Hospital for Sick Children (SickKids) have laid the groundwork for early detection of and future precision therapies for cardiomyopathy.

28 Feb 2024

Newborn T Cells Excel in Immune Response Compared to Adults

Scientists have long believed that a newborn's immune system was an immature version of an adult's, but new research from Cornell University shows that newborns' T cells – white blood cells that protect from disease – outperform those of adults at fighting off numerous infections.

26 Feb 2024