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Study Identifies Three Distinct Subtypes of Clear Cell Renal Cell Carcinoma Using Radiomics and Transcriptomics

Using transcriptomics and radiomics data clustering and its association with molecular characteristics, clinical pathologies, and prognosis to define intrinsic subtypes of ccRCC.

24 Jun 2024

Christchurch Variant Offers Protection Against Early-Onset Alzheimer's

A scientific story that began with a discovery in just one extraordinary patient is now panning out.

21 Jun 2024

Tabulae Paralytica: Mapping Cellular Dynamics in Spinal Cord Injuries

Scientists at EPFL have achieved a significant research milestone in the field of spinal cord injuries-;mapping out the cellular and molecular dynamics of paralysis in unprecedented detail with their open-source project 'Tabulae Paralytica'.

20 Jun 2024

Multimodal Imaging Reveals Heterogeneity in Amyloid Plaques

Alzheimer's disease (AD), which affects millions of people globally, is still one of the most difficult and common neurodegenerative conditions.

19 Jun 2024

Specific Population of "Time Cells" Found to be Essential for Learning Complex Behaviors

A sense of time is fundamental to how we understand, recall, and interact with the world.

19 Jun 2024

Breakthrough Imaging Reveals the Dynamics of the Brain's Fast-Acting Kainate Receptor

New groundbreaking images of one of the brain's fastest-acting proteins are providing critical clues that may lead to the development of targeted therapies to treat epilepsy and other brain disorders.

18 Jun 2024

Johns Hopkins Scientists Engineer Synthetic Cells to Mimic Symmetry Breaking

In a feat aimed at understanding how cells move and creating new ways to shuttle drugs through the body, scientists at Johns Hopkins Medicine say they have built a minimal synthetic cell that follows an external chemical cue and demonstrates a governing principle of biology called "symmetry breaking."

14 Jun 2024

New Platform Enables Ultra-Detailed Imaging of Human Brain Tissue

Researchers reveal that a novel technology allows for the simultaneous capture at many scales of neuronal projection, synapse distribution, cellular architecture, and protein expression in large-scale human brain tissues.

14 Jun 2024

New mosTF Microscopy System Enhances Real-Time Brain Plasticity Research

The brain's ability to learn comes from "plasticity," in which neurons constantly edit and remodel the tiny connections called synapses that they make with other neurons to form circuits.

6 Jun 2024

Sphere Fluidics Launches Cyto-CellectPLUS to Accelerate Cell Line Development Workflows

Sphere Fluidics, a leading provider of innovative microfluidics-based solutions for single-cell analysis and isolation, today announced the launch of Cyto-Cellect®PLUS.

From Sphere Fluidics Limited 5 Jun 2024

New Microscopy Reveals Secrets of SARS-CoV-2 Replication

Recent research published in Nature Communications by a Stanford University team may provide more accuracy in drug development by examining at the nanoscale how the SARS-CoV-2 virus replicates in cells.

4 Jun 2024

Azoles Trigger Two Self-Destruction Pathways in Fungi

Scientists have shown that the most common class of antifungals used worldwide induces microorganisms to self-destruct.

4 Jun 2024

Study Uncovers Fungal Self-Destruct Mechanism

Scientists have discovered that the most widely-used class of antifungals in the world cause pathogens to self-destruct.

3 Jun 2024

Non-Destructive Test Identifies Potent Cartilage Repair Cells

Researchers from Critical Analytics for Manufacturing Personalized-medicine (CAMP) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, and collaborators from the National University of Singapore Tissue Engineering Programme (NUSTEP) have discovered a more efficient method for evaluating the ability of mesenchymal stromal cells (MSCs) to regenerate cartilage.

3 Jun 2024

Structural Insights into a Novel Gene-Editing Tool

Yutaro Shuto, Ryoya Nakagawa, and Osamu Nureki of the University of Tokyo conducted collaborative research to ascertain the spatial organization of different processes within a unique gene-editing instrument known as “prime editor.”

30 May 2024

Newly Discovered CD8-fit Cells Could Revolutionize Cancer Treatment

A team of cancer researchers, led by the University of Houston, has discovered a new subset of T cells that may improve the outcome for patients treated with T-cell therapies.

30 May 2024

Unlocking the Secrets of Selective Pollen Attraction in Flowers

A team of scientists from Nagoya University in Japan employed a sophisticated microscopic technology to study the internal reproductive mechanism of the Arabidopsis plant.

22 May 2024

Sartorius Expands Collaboration with NVIDIA to Advance AI-Powered Drug Discovery

The life science group Sartorius is expanding its multidisciplinary collaboration with NVIDIA to help enable the development of new and better therapies, combining Sartorius’ in-depth knowledge of life sciences and bioprocessing with NVIDIA’s AI-powered computing platforms and software.

20 May 2024

Unlocking the Secrets of Childhood Cancer Genetics

Scientists have revealed a fresh insight into the genetic pathway of childhood cancer, providing new potential for personalized treatment.

15 May 2024

Bristle Biogenesis of Platynereis dumerilii: Microvilli as Nature's 3D Printers

A new interdisciplinary study led by molecular biologist Florian Raible from the Max Perutz Labs at the University of Vienna provides exciting insights into the bristles of the marine annelid worm Platynereis dumerilii.

14 May 2024