Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

RNA-edited regions in brain shed light on neurodevelopment and disease

Numerous sites in the brain where RNA is altered over the course of a person’s lifespan through a process known as adenosine-to-inosine (A-to-I) editing have been identified by Mount Sinai researchers.

3 Nov 2022

New tool advances potential means to deliver gene therapy

Researchers from Johns Hopkins Medicine claim to have successfully “slid” genetic instructions into a cell and produced essential proteins that were lacking from those cells using a cell’s normal process for creating proteins.

1 Nov 2022

Gene governing cell division could shield against Alzheimer’s

According to a recent study by researchers at the University of Colorado Anschutz Medical Campus, the overexpression of a gene linked to cell division and the structure and function of neurons could prevent and protect against cognitive deterioration in both mice and people with Alzheimer’s disease (AD).

28 Oct 2022

NATA accreditation for BGI Australia to perform whole exome sequencing

The National Association of Testing Authorities (NATA) has accredited BGI Australia’s lab to conduct clinical Whole Exome Sequencing in Australia, opening the door for the multinational life sciences company to offer clinical sequencing services for locating potential disease-causing genetic changes.

25 Oct 2022

The influence of fatty acid metabolism on plant immunity

Most people do not realize that fatty acids can be found in a nutritious salad. Although fatty acids, lipids, and fats may seem unappealing, they are essential to human life and to the plants that are consumed.

17 Oct 2022

Fungus can be used for biological control of banana borers and Fusarium wilt

The banana borer Cosmopolites sordidus and the disease Fusarium wilt, caused by the soil-borne fungus Fusarium oxysporum, are among the most harmful pests that threaten the livelihoods of banana growers, who face major challenges in attempting to control them.

29 Sep 2022

The exchange of nutrients between the mother and fetus mirrored by ‘placenta-on-a-chip’

Plasmodium falciparum infections can result in placental malaria, which can have serious consequences for both mother and child. Nearly 200,000 newborn fatalities annually from placental malaria, primarily as a result of low birth weight, as well as 10,000 maternal deaths.

27 Sep 2022

The master regulator behind the fungal infection of wheat identified

The most damaging fungal disease of wheat farmed in temperate regions worldwide, Septoria tritici blotch, is brought on by the fungus Zymoseptoria tritici.

From University of Exeter 27 Sep 2022

WEHI receives $2.5 million fund to develop personalized cancer treatments

With a $2.5 million fund received from the Medical Research Future Fund (MRFF), a new genomics project led by WEHI will develop precision medicine and customized cancer therapy for Australians.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 27 Sep 2022

New study supports bradykinin storm theory of COVID-19's viral pathogenesis

A new paper published in Nature Communications adds further evidence to the bradykinin storm theory of COVID-19's viral pathogenesis -; a theory that was posited two years ago by a team of researchers at the Department of Energy's Oak Ridge National Laboratory.

19 Sep 2022

Biotrophic fungus uses host auxin signaling pathway for its own purposes

Ustilago maydis attacks and reproduces in the aerial parts of the corn plant. At the location of the infection, massive tumor-like tissue growths frequently develop. The size of these galls can exceed that of a child’s skull.

12 Aug 2022

Researchers identify the molecular route that leads to autoimmune disease inflammation

Mitochondria are self-contained organelles that reside inside cells and are tasked with producing the chemical energy required to power vital tasks necessary for life and wellbeing. They have their own mini-chromosome and DNA.

From UC San Diego 14 Jul 2022

Challenges in Drug Discovery; Where are we now, and where are we going?

As part of our SLAS Europe 2022 coverage, we speak to Steve Rees, Vice-President of Discovery Biology at AstraZeneca, about the challenges currently faced by the drug discovery sector.

From Society for Laboratory Automation and Screening (SLAS) 8 Jul 2022

Researchers get funding to develop a vaccine against ALS disease

DZNE and Intravacc B.V., have received a grant from the European Union of € 2.5 million to further create a prototype ALS vaccine.

8 Jul 2022

Study highlights retrotransposition in CRISPR gene therapy clinical trials

Worldwide clinical studies for gene therapy utilizing CRISPR/Cas9 gene editing are now underway for a number of disorders. A study from Boston Children’s Hospital that was released in Nature Communications on June 27th, 2022, alerts readers to a possible CRISPR editing risk that has not yet been identified.

8 Jul 2022

Online version algorithm helps to detect ramp sequences of RNA, study finds

The significance of detecting and comprehending how variations between tissues and cells influence gene expression without altering the underlying genetic code is discussed in a recent study by University of Kentucky researchers.

1 Jul 2022

Researchers get deep insights into the functionality of human genome

Scientists from Weill Cornell Medicine and the New York Genome Center, in partnership with Oxford Nanopore Technologies, have introduced a new method for assessing the three-dimensional structure of the human genome, as well as how the genome folds, on a large scale.

27 Jun 2022

Research sheds light on innovative techniques to improve drugs for diseases

In a paper that was just published in Science, scientists from Sweden’s Karolinska Institutet and SciLifeLab explain how they were able to enhance a protein’s capacity to repair oxidative DNA damage while also giving the protein a new role.

27 Jun 2022

Study reveals that gene variant regulates protein level to prevent blood clots in the lungs

The probability of blood clots in the lungs of very sick COVID-19 patients is influenced by a gene variant in the natural immune system. This is demonstrated in a new study published in Nature Immunology by researchers from Uppsala University and Karolinska Institutet.

1 Jun 2022

New technique can reduce the incidence of leafroll disease in vineyards

Removing not only a diseased grapevine but the two vines on either side of it can reduce the incidence of leafroll disease, a long-standing bane of vineyards around the world, Cornell University researchers have found.

20 May 2022