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Domestication Drives Convergent Plant-Microbial Partnerships Across Continents

The communities of microorganisms connected to plants can change as a result of human domestication of crops, according to recent research headed by the University of Oxford.

17 Jan 2024

Implications of the KMAP Ocean Gene Catalog 1.0

The greatest investigation of ocean DNA reveals the diverse world of ocean bacteria. The KMAP Global Ocean Gene Catalog 1.0, an open-source database containing over 317 million gene groups, has the potential to stimulate biotechnology innovation and reveal the function of marine microbes in reducing global warming and preserving human and environmental health.

17 Jan 2024

Investigating the Functional Mechanisms of RNA Replicase

It has long been a mystery how the complex molecular machinery of life sprang from modest beginnings.

17 Jan 2024

Herts Awarded Its Biggest Ever Research Grant to Develop Biodetection Technologies Against Harmful, Airborne Pathogens

The University of Hertfordshire has been awarded £13.5million – its biggest ever research grant – to expand and progress its sector-leading, research-led development of biodetection technologies against harmful, airborne pathogens.

17 Jan 2024

‘Mini-Placentas’ Help Scientists Study the Causes of Pre-eclampsia and Pregnancy Disorders

Scientists have grown ‘mini-placentas’ in the lab and used them to see how the placenta develops and interacts with the inner lining of the womb – findings that could help scientists better understand and, in future, potentially treat pre-eclampsia.

17 Jan 2024

Uncovering the Role of Faulty Signalling in Immune Cell Development

An autoimmune disease occurs when the body’s own cells are attacked by the immune system in addition to external pathogens.

16 Jan 2024

The Role of Temperature and Land Cover in Shaping Arthropod Biodiversity

People rarely pay much attention to spiders and insects other than when humans swat them away. But as a hard exoskeleton and jointed legs identify arthropods, they are vital to maintaining the ecosystems upon which humans depend. Arthropods comprise an astounding 84% of all known animal species.

16 Jan 2024

The Crucial Role of Nucleolus Organizing Regions in Chestnut Genetics

The nucleolus organizing region (NOR), a crucial area of the genome, indicates that the chromosomes of Chinese and American chestnuts are not as comparable as previously thought.

16 Jan 2024

Genome-Wide Study Identifies Gene Pair Crucial for Regulating Blood Vessel Disease in the Lungs

University of Pittsburgh Schools of Medicine researchers uncovered a fundamental mechanism that controls the body's response to limited oxygen and regulates blood vessel disease of the lung.

16 Jan 2024

Mosaic Turner Syndrome Identified in 2500-Year-Old Briton: Ancient DNA Reveals Hidden History

Researchers at the Francis Crick Institute, working with University of Oxford, University of York and Oxford Archaeology, have developed a new technique to measure the number of chromosomes in ancient genomes more precisely, using it to identify the first prehistoric person with mosaic Turner syndrome (characterized by one X chromosome instead of two [XX]), who lived about 2500 years ago.

16 Jan 2024

Algal Blooms May Pose More Health Risks Than Previously Thought

Florida's 156-mile-long Indian River Lagoon (IRL) borders five different counties and has five inlets that connect the lagoon with the Atlantic Ocean.

16 Jan 2024

Honeybees Directly Provide Nutrients to Gut Bacteria

Bacteria have adapted to all terrestrial environments. Some have evolved to survive in the gut of animals, where they play an important role for their host; they provide energy by degrading indigestible food, they train and regulate the immune system, they protect against invasion by pathogenic bacteria, and they synthesize neuroactive molecules that regulate the behavior and cognition of their host.

16 Jan 2024

Using a Data-Driven Approach to Accelerate the Design Process for New Drugs

Researchers have developed a platform that combines automated experiments with AI to predict how chemicals will react with one another, which could accelerate the design process for new drugs.

16 Jan 2024

Genome Analysis Exposes How Fungal Infections Evade Drugs

Global fungal infections, which affect one billion people and cause 1.5 million deaths each year, are on the rise due to the increasing number of medical treatments that heighten vulnerability.

16 Jan 2024

Messenger RNA Therapy Could be Used to Correct Rare Liver Genetic Disease

By exploiting the technology used in Covid-19 vaccines, a team led by UCL, King's College London and Moderna scientists has created an effective therapy for a rare disease, in a study in mice, demonstrating the technology's potential therapeutic use in people.

16 Jan 2024

Breakthrough 3D Vascular Sheet Mimics Atherosclerosis for High-Throughput Drug Screening

A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, University of Alabama at Birmingham researchers report in the journal Biomaterials.

16 Jan 2024