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Virtual clinical trials could transform the development of new drugs

New cutting-edge research undertaken at the University of Leicester could revolutionize the way new drugs are developed and the way patients are cared for, through a pioneering new approach using virtual clinical trials.

8 Mar 2021

Promising drug targets identified for aggressive forms of cancers

Scientists have largely been producing transcriptomic data in an attempt to find clues about modified cellular pathways that may be fueling cancer behavior.

5 Mar 2021

Three new COVID-19 variants can evade antibodies that act against original virus

New research at Washington University School of Medicine in St. Louis indicates that three new, fast-spreading variants of the virus that cause COVID-19 can evade antibodies that work against the original form of the virus that sparked the pandemic.

5 Mar 2021

Engineered safety switch reduces CAR-T immunotherapy-related side effects

UNC Lineberger Comprehensive Cancer Center researchers have successfully used an experimental safety switch, incorporated as part of a chimeric antigen receptor T-cell (CAR-T) therapy, a type of immunotherapy, to reduce the severity of treatment side effects that sometimes occur.

5 Mar 2021

SARS-CoV-2 can make itself unrecognizable to immune response by T-killer cells through mutations

The body's immune response plays a crucial role in the course of a SARS-CoV-2 infection. In addition to antibodies, the so-called T-killer cells, are also responsible for detecting viruses in the body and eliminating them.

5 Mar 2021

New ways proposed to overcome barriers in COVID-19 response

An international research team is calling for better consolidation of bioinformatics, viral genetics, and public health to allow for better pandemic responses.

5 Mar 2021

Study shows causal relationship between neonatal antibody production and mother's microbiota

A healthy system of gut bacteria, or microbiota, is crucial to health: Gut bacteria not only aid with digestion, but also play an important role in the body's immune response. Infants, however, are not born with full-fledged gut microbiota, which makes it difficult for them to fight off intestinal infections.

4 Mar 2021

New software tool enables swift analysis of datasets generated from single-cell sequencing

A new software tool allows researchers to quickly query datasets generated from single-cell sequencing. Users can identify which cell types any combination of genes are active in.

4 Mar 2021

Study reveals new mechanism through which cells build “mini-muscles”

Research teams have revealed how the motor protein, called myosin, which is responsible for causing the contraction of skeletal muscles, also functions in non-muscle cells.

3 Mar 2021

Ultrasonic cleaning can clean food more effectively than current washing methods

New research has demonstrated that mild streams of water transporting sound and tiny air bubbles can remove bacteria from salad leaves more effectively.

3 Mar 2021

Researchers find effective combination of therapies for managing mitochondrial disease

Researchers have demonstrated how one combination of therapies may be beneficial for patients with mitochondrial respiratory chain disorders.

3 Mar 2021

New technique reveals the tricks that cancer cells use to avoid immunotherapies

By harnessing the immune system against cancer, immunotherapies have revolutionized the way some types of cancer are treated. But most patients--across cancer types--do not respond, and in most cases, scientists are at a loss as to why.

2 Mar 2021

Scientists gain new insights into ribosome formation to identify potential drug targets

Ribosome formation is viewed as a promising potential target for new antibacterial agents. Researchers from Charité - Universitätsmedizin Berlin have gained new insights into this multifaceted process.

2 Mar 2021

Researchers use science to take the guesswork out of cheese manufacturing

Making cheese leaves a lot to chance as a batch could be ripened for months or even years before a problem is discovered, which could send a prized batch of cheddar to be sold off cheap as an ingredient for processed cheese.

2 Mar 2021

UChicago-based team shares new details about Genomic Data Commons

The National Cancer Institute's Genomic Data Commons (GDC), launched in 2016 by then-Vice President Joseph Biden and hosted at the University of Chicago, has become one of the largest and most widely used resources in cancer genomics, with more than 3.3 petabytes of data from more than 65 projects and over 84,000 anonymized patient cases, serving more than 50,000 unique users each month.

1 Mar 2021

Researchers identify gene variant associated with childhood asthma

Researchers at Henry Ford Health System, as part of a national asthma collaborative, have identified a gene variant associated with childhood asthma that underscores the importance of including diverse patient populations in research studies.

1 Mar 2021

Increased levels of OAS1 protein may reduce the severity of COVID-19

Researchers at the Lady Davis Institute (LDI) at the Jewish General Hospital have discovered that increased levels of the protein OAS1 are associated with reduced mortality and less severe disease requiring ventilation among patients with COVID-19.

1 Mar 2021

Absence of TRIM37 protein boosts genetic instability in patients with Mulibrey syndrome

Researchers from the Andalusian Centre for Molecular Biology and Regenerative Medicine (CABIMER), in collaboration with the Swiss Institute for Experimental Cancer Research (ISREC) have studied the mechanisms behind the higher tendency of people with Mulibrey syndrome to develop tumors.

1 Mar 2021

Researchers sequence 64 human genomes at high resolution

After the successful conclusion of the “Human Genome Project”, an international research team has sequenced a total of 64 human genomes at high resolution.

26 Feb 2021

Multidisciplinary approaches for data management in omics research

Bioinformatics, and by extension omic sciences - the collective disciplines that are dependent on the use of extensive datasets of biological information - present a challenge of data management for researchers all over the world.

25 Feb 2021

Medicine News and Research

Virtual clinical trials could transform the development of new drugs

Promising drug targets identified for aggressive forms of cancers

Three new COVID-19 variants can evade antibodies that act against original virus

Engineered safety switch reduces CAR-T immunotherapy-related side effects

SARS-CoV-2 can make itself unrecognizable to immune response by T-killer cells through mutations

New ways proposed to overcome barriers in COVID-19 response

Study shows causal relationship between neonatal antibody production and mother's microbiota

New software tool enables swift analysis of datasets generated from single-cell sequencing

Study reveals new mechanism through which cells build “mini-muscles”

Ultrasonic cleaning can clean food more effectively than current washing methods

Researchers find effective combination of therapies for managing mitochondrial disease

New technique reveals the tricks that cancer cells use to avoid immunotherapies

Scientists gain new insights into ribosome formation to identify potential drug targets

Researchers use science to take the guesswork out of cheese manufacturing

UChicago-based team shares new details about Genomic Data Commons

Researchers identify gene variant associated with childhood asthma

Increased levels of OAS1 protein may reduce the severity of COVID-19

Absence of TRIM37 protein boosts genetic instability in patients with Mulibrey syndrome

Researchers sequence 64 human genomes at high resolution

Multidisciplinary approaches for data management in omics research

Driving Support for Pharmaceutical Testing Through Continuous Innovation

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Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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