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High-dose green tea extract may create liver damage in people with certain genetic variations

Long-term use of high-dose green tea extract may provide some protection against cancer, cardiovascular disease, obesity and type 2 diabetes, but it also may create liver damage in a small minority of the population.

2 Dec 2022

Figuring out how immune cells prevent cognitive decline

Could Alzheimer’s disease and other types of cognitive decline be caused by the underproduction of immune cells that are poorly understood? It might, according to a Rutgers study published in Nature Immunology, and increasing these cells could undo the harm.

From Rutgers University 1 Dec 2022

Newly developed tool helps snip out faulty genes in a safe manner

Scientists from the Massachusetts Institute of Technology (MIT) have come up with a new tool that has the potential to detach faulty genes and exchange them with new ones in a highly safe and effective way.

From Massachusetts Institute of Technology (MIT) 25 Nov 2022

Launch of stem cells into space to investigate stem cell aging

Lab tests on astronaut Scott Kelly’s blood cells after he returned from a year-long stay aboard the International Space Station (ISS) showed telomeric and pre-leukemic changes.

From UC San Diego 24 Nov 2022

Applying “programmable molecular scissors” to combat COVID-19 infection

As an approach that could be used to create a new class of antiviral drugs, synthetic biology was used by Cambridge scientists to artificially create enzymes programmed to attack the genetic code of SARS-CoV-2 and eliminate the virus.

17 Nov 2022

Treatment using CRISPR alleviates swelling attacks in hereditary angioedema patients

Hereditary angioedema (HAE) is a rare, genetic disorder characterized by severe, recurring, and unpredictable swelling attacks in various organs and tissues of the body, which can be painful, debilitating, and life-threatening.

11 Nov 2022

Puffer fish use non-toxic version of a powerful neurotoxin to communicate with each other

A delicacy in Japanese cuisine, puffer fish (fugu) also contain a lethal toxin. Improperly prepared puffer fish can cause the person eating it to experience food poisoning and a swift death.

11 Nov 2022

Regulating cholesterol production with novel protein

Everyone must have heard about cholesterol and how important it is to eat heart-healthy meals to keep it under control.

From The University of New South Wales (UNSW) 8 Nov 2022

Georgia Tech researchers develop a new biomaterial that could cure Type 1 diabetes

Insulin injections to treat Type 1 diabetes could become a thing of the past, but finding the cure faces many challenges.

4 Nov 2022

Rare and protective loss-of-function mutations offer possible NAFLD drug targets

A significant genome-wide association study on the nonalcoholic fatty liver disease (NAFLD) has just been published in Nature Genetics by researchers from Amgen subsidiary deCODE Genetics.

26 Oct 2022

A remarkable finding reorients attempts to cure liver disease

A long-running debate in gastroenterology has been settled by WEHI researchers who have shown that prevalent liver diseases are not caused by inflammatory cell death as previously believed.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 7 Oct 2022

Research team outlines three-step technique that lets human body defend against Hep B

A team from the University of Geneva (UNIGE) has unraveled the precise operation of this defensive mechanism after finding a crucial protein complex that is active when our body is infected by the virus, paving the path for novel treatment targets.

5 Oct 2022

The strategy used by metastatic cancer cells to invade the liver identified

The alternative pathway for liver metastasis has been revealed by a team of researchers.

5 Oct 2022

Using in vivo self-assembled siRNA as part of combination therapy for ulcerative colitis

There is still a large unmet medical need for the treatment of ulcerative colitis, despite recent improvements in the understanding of the pathogenic mechanisms of ulcerative colitis.

30 Sep 2022

Hemp byproducts can be included in lamb diets without major detrimental health effects

An Oregon State University study found that spent hemp biomass – the main byproduct of the cannabinoid (CBD) extraction process of hemp – can be included in lamb diets without any major detrimental effects to the health of the animals or their meat quality.

23 Sep 2022

Spatial transcriptomic data highlights the features of the axolotl brain

The first spatiotemporal cellular atlas of axolotl (Ambystoma mexicanum) brain growth and regeneration, created by a multi-institute research team under the direction of BGI-Research, reveals how brain damage may recover itself.

8 Sep 2022

Chromatin displays different dynamics in cells during organ-formation

Recent research from the School of Medicine has illuminated the development of the liver, lungs, and digestive system. This result may have significant ramifications for the comprehension of cancer.

30 Aug 2022

Study explains the dynamics underlying liver damage

The immune system may attack the liver when fat builds up there. The chemical that triggers these responses has been discovered by Weill Cornell Medicine researchers in a recent study, and this information helps to explain the dynamics of liver damage that can accompany type 2 diabetes and obesity.

23 Aug 2022

New method identifies human gut microbes that contribute to inflammatory diseases

Researchers at Cedars-Sinai have created a way to determine the human gut microorganisms that are most likely to cause a variety of inflammatory disorders, including obesity, liver disease, inflammatory bowel disease, cancer, and several neurological conditions.

22 Aug 2022

Extract from the roots of Rhodiola rosea may be effective for managing type 2 diabetes

A team of researchers led by the University of California, Irvine has discovered that treatment with an extract from the roots of the Rhodiola rosea plant might be effective for helping manage type 2 diabetes, showing promise as a safe and effective non-pharmaceutical alternative.

16 Aug 2022