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Deep learning-based technique could boost drug development

When you take a medication, you want to know precisely what it does. Pharmaceutical companies go through extensive testing to ensure that you do.

6 Oct 2020

Researchers identify the cause for Parkinson's disease and potential treatments

In a seven-year research effort, an international team of scientists has clarified the cause for certain genetic forms of Parkinson's disease, and has identified potential pharmacological treatments.

14 Sep 2020

Allergic immune responses protect against bacterial infections

Allergy is one of the most common diseases in Europe, it is estimated that more than 150 million Europeans suffer from recurring allergies and by 2025 this could have increased to half of the entire European population.

10 Sep 2020

Researchers develop antibacterial agent to treat drug-resistant infections

Methicillin-resistant Staphylococcus aureus (MRSA) is the most lethal drug-resistant bacteria and is also one of the most common bacterial pathogens.

3 Sep 2020

Largely ignored 'housekeeping' gene plays unexpected role in neurological diseases

Within cells, molecules known as transfer RNAs, or "tRNAs," play an important but unglamorous workhorse role in keeping the genetic translation process moving along from codes of DNA to functional proteins.

27 Aug 2020

Eliminating tumors with engineered ‘off-the-shelf’ therapeutic T cells

Personalized cancer treatments are no longer just options of the future. In the past few years, researchers have made significant progress in 'teaching' the body's immune T cells to recognize and kill specific cancer cells, and human clinical trials have shown that this approach can successfully eliminate tumors

21 Aug 2020

'Genetic Code Kit' could transform how biology and biochemistry are taught

An open-source educational biotechnology called the "Genetic Code Kit" has been developed by California Polytechnic State University researchers to allow students to interact with the molecular process inside cells in new ways.

20 Aug 2020

Shielded stem cells can improve heart healing

Ghanta, R.K., et al. (2020) Immune-modulatory alginate protects mesenchymal stem cells for sustained delivery of reparative factors to ischemic myocardium. Biomaterials Science. doi.org/10.1039/D0BM00855A.

19 Aug 2020

A genetic link discovered to predict treatment response for patients with rare, aggressive cancer

A Singapore team led by clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS) discovered a genetic link to better predict treatment response for relapsed/refractory patients with natural- killer T-cell lymphoma (NKTCL), a highly aggressive form of blood cancer.

13 Aug 2020

Deep Learning On Cell Signaling Networks Establishes AI For Single-Cell Biology

Computer systems that emulate key aspects of human problem solving are commonly referred to as AI. This field has seen massive progress over the last years.

6 Aug 2020

Researchers develop new models to study molecular characteristics of lung and pancreatic cancers

Scientists at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) report today the development of new models to study molecular characteristics of tumors of the lung and pancreas.

5 Aug 2020

A New Way of Killing Tuberculosis

AZoLifeSciences speaks to Dr. Tim Blower about his research into tuberculosis, and how the discovery of a new toxin could lead to new anti-TB drugs.

From Durham University 5 Aug 2020

'Little brain' contains almost 80% of the cerebral cortex’s surface area

When we say someone has a quick mind, it may be in part thanks to our expanded cerebellum that distinguishes human brains from those of macaque monkeys, for example.

3 Aug 2020

Study shows genetic mutations allow MRSA to develop antibiotic resistance

Researchers have discovered that genetic mutations that occur in MRSA enable it to evolve and turn out to be more resistant to antibiotics like penicillin.

27 Jul 2020

Study shows the efficacy of plant-based diet on blood pressure

Consuming a plant-based diet can lower blood pressure even if small amounts of meat and dairy are consumed too, according to new research from the University of Warwick.

From The University of Warwick 27 Jul 2020

Study shows efficacy of L-Grb2 in preclinical models of ovarian and uterine cancer

The cover for issue 29 of Oncotarget features Figure 5, "In vivo effects of treatment with L-Grb2 in combination with anti-angiogenic therapy in an ovarian tumor model," by Lara, et al. which reported that adaptor proteins such as growth factor receptor-bound protein-2 play important roles in cancer cell signaling.

23 Jul 2020

New startup launched to overcome the challenge of delivering next-generation therapeutics

Harvard University's Office of Technology Development (OTD) and the Harvard T.H. Chan School of Public Health today announced the launch of Vesigen Therapeutics, a startup company that aims to overcome the challenge of delivering next-generation therapeutics, such as gene-editing complexes, RNA molecules, and other large proteins, to intracellular targets in specific tissues of interest.

23 Jul 2020

Researchers estimate the cost-effectiveness and health impact of BRCA testing

Screening entire populations for breast and ovarian cancer gene mutations could prevent millions more breast and ovarian cancer cases across the world compared to current clinical practice, according to an international study led by Queen Mary University of London.

20 Jul 2020

SARS-CoV-2 protein effectively shuts down host protein production, shows study

A detailed study of a SARS-Cov-2 protein, Nsp1, with a central role in weakening the host anti-viral immune response shows that it effectively shuts down production ofproteins in the host.

20 Jul 2020