Cancer News and Research

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Cancer begins in your cells, which are the building blocks of your body. Normally, your body forms new cells as you need them, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should. These extra cells can form a mass called a tumor. Tumors can be benign or malignant. Benign tumors aren't cancer while malignant ones are. Cells from malignant tumors can invade nearby tissues. They can also break away and spread to other parts of the body.

Tumor DNA in DLBCL patient's stem cells or blood can predict risk of relapse after transplant

Many patients with diffuse large B-cell lymphoma (DLBCL) can be cured by a transplant using their own blood-forming stem cells, but as many as half eventually relapse. New research led by Dana-Farber Cancer Institute scientists suggests that patients whose blood or stem cell samples harbor tumor DNA are likely to relapse.

8 Dec 2020

Study: CAR T cell therapy is a safe, effective therapy for high-risk large B-cell lymphoma

A study led by researchers at The University of Texas MD Anderson Cancer Center found that axi-cel, an autologous anti-CD19 chimeric antigen receptor (CAR) T cell therapy, is a safe and effective first-line therapy for patients with high-risk large B-cell lymphoma (LBCL), a group with an urgent need for new and effective treatments.

8 Dec 2020

Mice infused with CD5-deleted CAR T cells showed significant reduction in tumor size

Knocking out a protein known to stifle T cell activation on CAR T cells using the CRISPR/Cas9 technology enhanced the engineered T cells' ability to eliminate blood cancers, according to new preclinical data from researchers in the Perelman School of Medicine at the University of Pennsylvania and Penn's Abramson Cancer Center.

8 Dec 2020

Researchers target pathogenic T cells that could lead to new immunotherapy treatments

According to a new study, a novel T cell genetically engineered by scientists from The University of Arizona Health Sciences can target and attack pathogenic T cells that are responsible for causing Type 1 diabetes. These latest findings may result in new immunotherapy therapies.

7 Dec 2020

CAR T-cell therapy reduced cancer cells in patients with advanced non-Hodgkin lymphoma

A CAR T-cell therapy known as axicabtagene ciloleucel (axi-cel) drove cancer cells to undetectable levels in nearly 80% of patients with advanced non-Hodgkin lymphoma (NHL) in a phase 2 clinical trial, Dana-Farber Cancer Institute investigators report at the virtual 62nd American Society of Hematology (ASH) Annual Meeting.

7 Dec 2020

Subcutaneous injection of teclistamab drug shows promise in treating aggressive multiple myeloma

A subcutaneous injection of the immune-boosting drug teclistamab was found to be safe and elicit responses in a majority of patients with relapsed or refractory multiple myeloma, according to findings from a multi-institutional phase I study being presented by Alfred L. Garfall, MD, an assistant professor of Medicine in the division of Hematology-Oncology in the Perelman School of Medicine at the University of Pennsylvania, at the annual American Society of Hematology & Exposition Meeting on Dec. 5 (abstract #180).

7 Dec 2020

Biochemist discovers hidden cellular machinery essential for higher-order life

In his first year of graduate school, Rice University biochemist Zachary Wright discovered something hidden inside a common piece of cellular machinery that's essential for all higher order life from yeast to humans.

7 Dec 2020

Scientists reveal health benefits of clonal hematopoiesis in allogeneic transplants

Clonal hematopoiesis (CH) is a recently identified condition in which mutations associated with blood cancers are detected in the blood of some healthy, usually older, individuals who don't have cancer. People with CH, while asymptomatic, have an elevated risk of developing blood cancers and other negative health outcomes, including heart attacks and strokes.

7 Dec 2020

Study explains new associations between Neanderthal DNA and autoimmune diseases

A researcher at the University of Tartu described new associations between Neanderthal DNA and autoimmune diseases, prostate cancer and type 2 diabetes.

4 Dec 2020

Single-walled nanotubes emit delayed secondary fluorescence when triggered by multistep process

That carbon nanotubes fluoresce is no longer a surprise. Finding a second level of fluorescence is surprising and potentially useful.

4 Dec 2020

Study may lead to novel organisms that are more efficient at converting plants into biofuels

A new study reveals how bacteria control the chemicals produced from consuming 'food.' The insight could lead to organisms that are more efficient at converting plants into biofuels.

4 Dec 2020

A Gene Mutation That Protects Against Disease

Researchers think they have found a fountain of youth, and it is unique to a few French Canadian families.

3 Dec 2020

Environmental and exogenous compounds can interact with therapeutic drugs, shows study

According to scientific estimations, humans are exposed to at least 10,000 to 100,000 environmental and exogenous compounds in an individual lifetime, which are mainly absorbed through our dietary.

3 Dec 2020

New breakthrough in microscopy and endoscopy may advance the field of precision medicine

A breakthrough in microscopy and endoscopy will soon revolutionize the study of the cellular origin of diseases, advancing the field of precision medicine.

3 Dec 2020

Gene editing technology can introduce diversity, improve nutrition of tomatoes

Whether tomatoes are fresh, cooked, juiced, or sun-dried, they are arguably one of the most multipurpose fruits on Earth.

2 Dec 2020

Study identifies a promising target for cancer treatment

If there is a positive aspect in cancer’s random biology, it is that the same characteristics that promote the growth of cancer cells usually present opportunities for destroying them.

2 Dec 2020

New patented technique reveals the energy status of cells

Scientists have developed a novel process that may help personalize anticancer treatments.

2 Dec 2020

Researchers identify key target that allows cancer cells to spread more efficiently

Cancer cells spread by switching on and off abilities to sense their surroundings, move, hide and grow new tumours, a new study has found.

2 Dec 2020

Study confirms that telomere shortening helps prevent cancer in humans

As time goes by, the tips of your chromosomes--called telomeres--become shorter. This process has long been viewed as an unwanted side-effect of aging, but a recent study shows it is in fact good for you.

2 Dec 2020

Study: Gut microbiota directly shapes the makeup of human immune system

In recent years, the microbiota -- the community of bacteria and other microorganisms that live on and in the human body -- has captured the attention of scientists and the public, in part because it's become easier to study. It has been linked to many aspects of human health.

1 Dec 2020

Cancer News and Research

Tumor DNA in DLBCL patient's stem cells or blood can predict risk of relapse after transplant

Study: CAR T cell therapy is a safe, effective therapy for high-risk large B-cell lymphoma

Mice infused with CD5-deleted CAR T cells showed significant reduction in tumor size

Researchers target pathogenic T cells that could lead to new immunotherapy treatments

CAR T-cell therapy reduced cancer cells in patients with advanced non-Hodgkin lymphoma

Subcutaneous injection of teclistamab drug shows promise in treating aggressive multiple myeloma

Biochemist discovers hidden cellular machinery essential for higher-order life

Scientists reveal health benefits of clonal hematopoiesis in allogeneic transplants

Study explains new associations between Neanderthal DNA and autoimmune diseases

Single-walled nanotubes emit delayed secondary fluorescence when triggered by multistep process

Study may lead to novel organisms that are more efficient at converting plants into biofuels

A Gene Mutation That Protects Against Disease

Environmental and exogenous compounds can interact with therapeutic drugs, shows study

New breakthrough in microscopy and endoscopy may advance the field of precision medicine

Gene editing technology can introduce diversity, improve nutrition of tomatoes

Study identifies a promising target for cancer treatment

New patented technique reveals the energy status of cells

Researchers identify key target that allows cancer cells to spread more efficiently

Study confirms that telomere shortening helps prevent cancer in humans

Study: Gut microbiota directly shapes the makeup of human immune system

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