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'Training’ the innate immunity may improve the success of immunotherapy

Immunotherapies, such as checkpoint inhibitor drugs, have made worlds of difference for the treatment of cancer. Most clinicians and scientists understand these drugs to act on what's known as the adaptive immune system, the T cells and B cells that respond to specific threats to the body.

30 Oct 2020

Research projects receive BTCA awards to develop new drugs

Five research projects with exceptional promise to deliver new life-changing and health-altering therapies have received the inaugural Blavatnik Therapeutics Challenge Awards (BTCA) at Harvard Medical School.

From Harvard Medical School 30 Oct 2020

Severe ulcerative colitis linked to newly-discovered strain of oral bacteria

Severe ulcerative colitis - a form of inflammatory bowel disease (IBD) - has been linked to a newly-discovered strain of oral bacteria, a study led by UNSW Sydney has found.

From The University of New South Wales (UNSW) 30 Oct 2020

Novel process turns waste materials into nutritional supplements

The shells of crustaceans and wood waste such as branches pruned from trees usually end up in landfills. These waste materials are given a new lease of life to become nutritional supplements and medicine, with the help of a novel process developed by researchers from the National University of Singapore (NUS).

30 Oct 2020

Researchers describe how drug use change specific brain cells responsible for motivation

In the October 28, 2020 issue of the Journal of Neuroscience, researchers from the Medical University of South Carolina and the National Institutes of Health describe how reminders of drug use can change specific brain cells responsible for motivation, increasing the desire to seek drugs.

30 Oct 2020

Scientists discover link between two signaling pathways crucial to growth of colon cancer

In breakthrough colon cancer research, scientists at ChristianaCare's Helen F. Graham Cancer Center & Research Institute have discovered a link between two key signaling pathways crucial to the development and growth of colon cancer. The study is published today in the journal PLOS ONE.

29 Oct 2020

Individuals infected with mild-to-moderate COVID 19 mount a robust antibody response

The vast majority of individuals infected with mild-to-moderate COVID 19 mount a robust antibody response that is relatively stable for at least five months, according to research conducted at the Icahn School of Medicine at Mount Sinai and published October 28, in the journal Science.

29 Oct 2020

Researchers are decoding the genetics of agricultural pests

The University of Cincinnati is decoding the genetics of agricultural pests in projects that could help boost crop and livestock production to feed millions more people around the world.

29 Oct 2020

Scientists develop controllable system for mimicking biochemical reaction cascades in cells

Researchers at the University of Basel have developed a precisely controllable system for mimicking biochemical reaction cascades in cells. Using microfluidic technology, they produce miniature polymeric reaction containers equipped with the desired properties.

29 Oct 2020

Genetic predispositions affect the efficacy of COVID-19 drugs

A paper recently uploaded to bioRxiv* aimed to utilize genome-wide CRISPR screening to identify genes involved in modulating the activity of COVID-19 drugs.

29 Oct 2020

Study shows genetic analysis with RNA sequencing can increase diagnostic yield

In the world of rare genetic diseases, exome and genome sequencing are two powerful tools used to make a diagnosis.

28 Oct 2020

Specific metabolites can predict COVID-19 mortality

A new study from Lawson Health Research Institute, Western University and University of Alberta suggests that COVID-19 affects the human body's blood concentration levels of specific metabolites - small molecules broken down in the human body through the process of metabolism.

28 Oct 2020

Researchers develop new sensors to detect gene activity

A team of researchers have developed genetic sensors that are capable of detecting the activity of genes, instead of only the genes themselves.

From The University of Warwick 27 Oct 2020

Proviral and antiviral genes may help develop new therapies for COVID-19

Scientists have screened an unlimited number of cells exposed to the COVID-19 virus and detected genes that appear to close the door on the virus.

27 Oct 2020

Anti-inflammatory mediator could play key role in wound healing

"Wound healing is one of the most complex biological processes," writes Professor Kazumitsu Sugiura and Dr Kenta Saito from Fujita Health University, Japan, in their article recently published in Nature's Scientific Reports.

27 Oct 2020

Dual-chip system for monitoring heart toxicity from breast cancer drugs

Breast cancer is the most commonly occurring cancer for women around the world, and much effort has been spent in the development of therapies to treat this disease.

27 Oct 2020

Researchers discover new ways to block the colonization and spread of tumor cells

What role do the lymphatic vessels play in the metastasis of cancer cells? Scientists from the German Cancer Research Center and the Mannheim Medical Faculty of the University of Heidelberg developed a method to investigate this question in mice.

27 Oct 2020

Scientists develop human airway stem cells to accelerate research on COVID-19, influenza

For the first time, researchers have successfully created airway basal stem cells in vitro from induced pluripotent stem cells by reprogramming blood cells taken from patients.

27 Oct 2020

Study shows potential avenues of COVID-19 vulnerability in patients with diabetic kidney disease

People with diabetes -- especially the 20 to 40 percent with diabetic kidney disease -- are among the most at risk for serious complications and death from COVID-19.

27 Oct 2020

Targeting DEL-1 molecule could be an effective way to treat autoimmune disease

Immune response is a balancing act: Too much can lead to inflammatory or autoimmune disease; too little could lead to a serious infection. Regulatory T cells, or Tregs, are important players in striking this balance, acting as "brakes" on the immune response so it doesn't go overboard.

27 Oct 2020

Medicine News and Research

'Training’ the innate immunity may improve the success of immunotherapy

Research projects receive BTCA awards to develop new drugs

Severe ulcerative colitis linked to newly-discovered strain of oral bacteria

Novel process turns waste materials into nutritional supplements

Researchers describe how drug use change specific brain cells responsible for motivation

Scientists discover link between two signaling pathways crucial to growth of colon cancer

Individuals infected with mild-to-moderate COVID 19 mount a robust antibody response

Researchers are decoding the genetics of agricultural pests

Scientists develop controllable system for mimicking biochemical reaction cascades in cells

Genetic predispositions affect the efficacy of COVID-19 drugs

Study shows genetic analysis with RNA sequencing can increase diagnostic yield

Specific metabolites can predict COVID-19 mortality

Researchers develop new sensors to detect gene activity

Proviral and antiviral genes may help develop new therapies for COVID-19

Anti-inflammatory mediator could play key role in wound healing

Dual-chip system for monitoring heart toxicity from breast cancer drugs

Researchers discover new ways to block the colonization and spread of tumor cells

Scientists develop human airway stem cells to accelerate research on COVID-19, influenza

Study shows potential avenues of COVID-19 vulnerability in patients with diabetic kidney disease

Targeting DEL-1 molecule could be an effective way to treat autoimmune disease

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