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A gene is a unit of heredity in a living organism. It normally resides on a stretch of DNA that codes for a type of protein or for an RNA chain that has a function in the organism. All living things depend on genes, as they specify all proteins and functional RNA chains.

New “genome scalpel” can rapidly trim microalgal genomes

A single-celled alga removes non-essential pieces by undergoing genome surgery.

18 Mar 2021

Study shows beneficial effects of gene therapy can be observed even after several decades

A new study shows that the advantageous effects of gene therapy can be observed several decades after the body clears the transplanted blood stem cells.

From University College London 18 Mar 2021

Study provides clues for designing more effective antiviral drugs

An international research team from the University of Turku based in Finland and PennState University based in the United States has solved an ancient puzzle of how living organisms differentiate between DNA and RNA building blocks at the time of gene expression, offering new possibilities for designing novel antiviral medications.

18 Mar 2021

New highly sensitive RNA detection method advances in situ transcriptomics

Human cells typically transcribe half of their roughly 20,000 genes into RNA molecules at any given time. Just like with proteins, the function of those RNA species not only relies on their abundance but also their precise localization within the 3D space of each cell.

18 Mar 2021

Mitigating the negative impacts of artificial light at night on wildlife

Artificial light at night (ALAN) is a major factor in global insect decline. In a paper published today in Insect Conservation and Diversity, Smithsonian Conservation Biology Institute (SCBI) scientists and partners found that using amber-colored filters to remove the blue spectra of light from "warm white" LED (light-emitting diode) lamps drastically reduces insect attraction to nocturnal lighting in a tropical forest.

18 Mar 2021

Scientists provide a complete phenotypic landscape of SCN2A-related disorders

Researchers from Children's Hospital of Philadelphia (CHOP) affiliated with the CHOP Epilepsy Neurogenetics Initiative (ENGIN) have compiled a complete genetic and clinical analysis of more than 400 individuals with SCN2A-related disorder, which has been linked to a variety of neurodevelopmental disorders, including epilepsy and autism.

18 Mar 2021

Genetic flaw shows promise for treating eye disease

A genetic flaw may hold the key to delay or prevent the onset of a serious eye disorder that can result in blindness and vision loss.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 17 Mar 2021

Study shows how human viruses are better adapted to infect certain tissues

The world’s first systematic study has explained how SARS-CoV-2 and other human viruses are more adapted to infect specific types of tissues..

17 Mar 2021

High-resolution map of yeast genome can shed light on development responses in higher organisms

A new study explains an effort to create the most detailed and high-resolution map of gene regulation and chromosome architecture in yeast organisms.

15 Mar 2021

ADAR1 protein offers a potential therapeutic target for cancer

A research team has discovered a new role of ADAR1 and found that the ADAR1p110 isoform controls genome stability at the ends of chromosomes.

15 Mar 2021

Cryogenic electron microscopy helps visualize 3D structure of complex responsible for gene regulation

A research team has looked inside a human cell to visualize a multi-subunit machine that is responsible for controlling the expression of genes.

15 Mar 2021

New gene editor could help treat genetic disorders caused by single-nucleotide mutations

Scientists have created a CRISPR-based gene editor named C-to-G Base Editor (CGBE) that can correct mutations responsible for genetic disorders.

15 Mar 2021

Optimized nano-micelles can induce efficient genome editing in mouse brain

A research team has reported that improved nano-micelles can trigger efficient genome editing in the mouse brain.

15 Mar 2021

Revealing clues about the immune system through ancient DNA

AZoLifeSciences speaks to Dr. Gaspard Kerner about tuberculosis, and how ancient DNA could help us to further understand the immune system.

From Institut Pasteur 12 Mar 2021

Study reveals mechanisms behind the activation of MRN complex

Researchers from the Tokyo Institute of Technology have revealed mechanisms behind the stimulation of the MRN complex—the DNA scissors of the cells.

11 Mar 2021

Study reveals mechanism that regulates genes on sex chromosomes

In the human population, males have one X and one Y chromosomes and females have two X chromosomes. As a result, somatic cells have unique mechanisms that maintain the same gene expression levels on the X chromosome between both genders.

10 Mar 2021

RNA-editing events can reveal the genetic basis of many human diseases

Scientists from CHOP have detected RNA-editing events that affect the expression of genes and the phenotypic manifestation of that specific expression.

10 Mar 2021

Study offers fresh insights into infection process during spaceflight

Astronauts face many challenges to their health, due to the exceptional conditions of spaceflight. Among these are a variety of infectious microbes that can attack their suppressed immune systems.

10 Mar 2021

Comprehensive mutation map helps better understand the biological processes underlying Alzheimer's

A study published in the journal eLife made all the possible mutations in the amyloid beta peptide and tested how they influence its aggregation into plaques, a pathological hallmark of Alzheimer's disease.

10 Mar 2021

Study identifies genes responsible for peach's tolerance to stress

A Boyce Thompson Institute-led team has identified genes enabling peaches and their wild relatives to tolerate stressful conditions -- findings that could help the domesticated peach adapt to climate change.

10 Mar 2021