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DNA Sequence Variants Drive Link Between Methylation and Gene Expression

The relationship between DNA methylation and gene expression is driven by sequence variants, according to a recent study conducted by researchers at deCODE Genetics, an Amgen subsidiary.

25 Jul 2024

Researchers Discover Genes Key to Spitting Cobra Venom's Cytotoxicity

Functional genomics to dissect and understand the cytotoxicity of spitting cobra venom and define the genetic interactions between the venom and the target to develop a locally acting antidote.

25 Jul 2024

Macrolones Offer Promising Strategy for Combating Resistant Bacteria

New research from the University of Illinois Chicago suggests that a novel antibiotic that disrupts two distinct cellular targets would make it 100 million times harder for bacteria to evolve resistance.

24 Jul 2024

New Tool GeneMAP Unveils Key Insights into Cell Metabolism

There's a glaring gap in our knowledge of cell metabolism: in many cases, we still don't know exactly how nutrients are transported into the cell.

24 Jul 2024

New RNA Sequencing Dataset Reveals Genetic Diversity Across Global Populations

An open-access dataset of RNA sequences from lymphoblastoid cell lines of 731 individuals spanning 26 populations and five continental groups.

24 Jul 2024

RNA Technology Enables Precise Control of Gene Networks

Scientists have created a smart RNA that can control networks in response to different signals by converting guide RNAs, which normally direct enzymes. The scholarly community is paying close attention to this ground-breaking study.

23 Jul 2024

Cell Dynamics Drive Dramatic Shape Changes in Insect Development

A small leg might uncover significant insights into how closely related insect species can exhibit dramatic differences in body shape, according to a new study led by researchers at the University of Tokyo.

23 Jul 2024

Study Identifies Microproteins as Key Source of Tumor-Specific Antigens in Liver Cancer

If microproteins translated from noncanonical open reading frames (ncORFS) in long noncoding ribonucleic acids (RNAs) could be a potential source of tumor-specific antigens.

23 Jul 2024

Developing DNA Test to Eliminate Inherited Blindness in English Shepherd Dogs

Researchers at Cambridge have discovered the genetic mutation that causes English Shepherd Dogs to suffer from progressive retinal atrophy, an irreversible form of blindness.

22 Jul 2024

Genomic Insights into Prunus Species Evolution and Traits

The Prunus genus, encompassing apricots, peaches, plums, and mei, is vital due to its economic and nutritional value.

22 Jul 2024

UNC Charlotte Study: SARS-CoV-2 Variants BA.2.86 and JN.1 Show Minimal Immune Evasion

New research from UNC Charlotte's Center for Computational Intelligence to Predict Health and Environmental Risks (CIPHER) has found that the two recent and prevalent strains of the virus that cause COVID-19, SARS-CoV-2 variants BA.2.86 and JN.1, are not significantly better than their predecessor Omicron at evading immune responses and causing infections despite having a high number of mutations compared to Omicron.

22 Jul 2024

Rhythmic Gene Expression Regulates Root Nodule Formation in Legumes

Legumes thrive in low-nitrogen environments by partnering with rhizobia, soil bacteria that convert atmospheric nitrogen into ammonium, a usable form for the plants.

22 Jul 2024

How Tiny Freshwater Animals Utilize Bacterial DNA to Fight Fungal Infections

A group of small, freshwater animals protect themselves from infections using antibiotic recipes "stolen" from bacteria, according to new research by a team from the University of Oxford, the University of Stirling and the Marine Biological Laboratory (MBL), Woods Hole.

19 Jul 2024

Ginseng Genome Map Unlocks New Possibilities for Medicinal Applications

A landmark study has successfully decoded the complete ginseng genome, unveiling the genetic mechanisms that govern saponin biosynthesis. This detailed genetic map illuminates the evolutionary and metabolic pathways of Panax ginseng, a staple in traditional medicine.

19 Jul 2024

Global Gene Expression Data Improves Precision in Genetics

The majority of human genetics research has traditionally concentrated on individuals with European ancestry, a long-standing bias that may reduce the precision of scientific predictions for individuals from other populations.

18 Jul 2024

New Model Reveals Interplay Between Circadian Rhythms and Sleep-Wake Cycles in Gene Expression

A mathematical, driven, damped harmonic oscillator model to assess the varying contributions of circadian cues and sleep-wake processes on gene expression and the rhythmic transcriptome.

18 Jul 2024

Vps21 Pathway's Role in Morphological Transitions and Mating of Candida albicans

This study was led by Dr. Guanghua Huang (School of Life Sciences, Fudan University). The team discovered that the conserved Vps21 signaling pathway plays critical roles in the regulation of white-opaque switching and mating in Candida albicans, a major human fungal pathogen.

18 Jul 2024