Metabolism News and Research

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Metabolism is the means by which the body derives energy and synthesizes the other molecules it needs from the fats, carbohydrates and proteins we eat as food, by enzymatic reactions helped by minerals and vitamins.

RNA Regulatory Mechanism Involving Stress Granules Directly Regulates Alzheimer’s Development

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 10, entitled, "Stress granules sequester Alzheimer's disease-associated gene transcripts and regulate disease-related neuronal proteostasis."

2 Jun 2023

Antioxidant Enzymes Relocate to the Nucleus in Response to DNA Damage

In crisis, the nucleus calls antioxidant enzymes to the rescue. The nucleus being metabolically active is a profound paradigm shift with implications for cancer research.

2 Jun 2023

Study Characterizes the Properties of MAIT Cells in Mouse Lung

A population of unconventional white blood cells has recently captured the attention of immunologists and clinicians alike.

26 May 2023

New Platform for Production of Synthetic Nitrated Proteins in Bacteria

In this study, the researchers focused on para-nitro-L-phenylalanine (pN-Phe), a non-standard amino acid that is neither one of the twenty standard amino acids nor been observed in nature.

24 May 2023

Identifying Drugs to Put the Brakes On Accelerated Aging From HIV Infection, Treatment

Antiretroviral cocktails can make human immunodeficiency virus, or HIV, undetectable and untransmittable, but both the virus and its treatment can also accelerate aging of bone and muscle.

24 May 2023

Study Shows How Excess Dietary Sugar Worsens IBD Symptoms

Excess sugar hampers cells that renew the colon's lining in a mouse model of inflammatory bowel disease (IBD), according to a new study by University of Pittsburgh scientists.

23 May 2023

New Insight into the Dynamics of a Ribosomal Protein - RPL3L

A team of researchers have discovered that a mutation in a ribosomal protein found specifically in heart and skeletal muscle leads to impaired cardiac contractility in mice.

23 May 2023

Researchers Develop AI Method to Predict Small Molecule Substrates of Enzymes

Enzymes are the molecule factories in biological cells. However, which basic molecular building blocks they use to assemble target molecules is often unknown and difficult to measure.

23 May 2023

Researchers Examine the Role of TOR in LR Formation and its Interplay with Auxin Signaling

Along with sugar reallocation, a basic molecular mechanism within plants controls the formation of new lateral roots. An international team of plant biologists has demonstrated that it is based on the activity of a certain factor, the target of rapamycin (TOR) protein. A better understanding of the processes that regulate root branching at the molecular level could contribute to improving plant growth and therefore crop yields, according to research team leader Prof. Dr Alexis Maizel of the Centre for Organismal Studies at Heidelberg University.

23 May 2023

Untangling the Effects of Admixture on the Genomes of Modern Humans

The course of human history has been marked by complex patterns of migration, isolation, and admixture, the latter a term that refers to gene flow between individuals from different populations.

22 May 2023

Targeting Cellular Respiration for the Treatment of Glioblastoma

A new research perspective was published in Oncotarget's Volume 14 on May 4, 2023, entitled, "Targeting cellular respiration as a therapeutic strategy in glioblastoma."

22 May 2023

A High-Throughput Assay for Identifying and Validating ECHS1 Enzyme Genetic Variants

The enzyme variations of mitochondrial enoyl-CoA hydratase short-chain 1 (ECHS1) are dysfunctional. In Japan, they are mostly responsible for mitochondrial disease.

19 May 2023

Liver Cells Influence the Body's Internal Circadian Clock, Study Reveals

University of Queensland-led research has revealed liver cells influence the body's internal circadian clock, which was previously believed to be solely controlled by the brain.

18 May 2023

Researchers Use the Bionanoprobe to Explore Role of Zinc in Follicle Development

The discovery that zinc is involved in the fertilization process earlier than initially thought was made with the help of the Bionanoprobe, a cutting-edge instrument at Argonne.

18 May 2023

Increase in Certain Bacterial Species Indicates Intestinal Candida Fungi Overgrowth

The bacteria present in the intestine provide information about the quantities of fungi of the potentially disease-causing Candida genus.

15 May 2023

High-Throughput Technique Observes Differences in Hard and Non-Hard Seeds

Alfalfa (Medicago sativa), also known as the “King of Grass,” is a legume cultivated in various parts of the world for animal feed. It is highly valued in the feed business because of its high protein content and biomass output.

8 May 2023

The Efficiency of AI in Microbial Experiments

An artificial intelligence system facilitates robots to perform independent scientific experiments—as many as 10,000/day—possibly taking a big step ahead in the speed of discovery in fields from medicine to environmental science to agriculture.

5 May 2023

Analyzing the Complex Sequence of Events Involved in Beta-Arrestin Interactions

Proteins that work like air traffic controllers, controlling the flow of signals in and out of human cells, have been examined in unparalleled detail for the first time using modern microscope techniques.

5 May 2023

Understanding How Diet may Influence the Gut Microbiota Structure

We know that eating a healthy diet affects body weight, cholesterol levels, and heart health. A new study from the University of Illinois focuses on another component: the role of diet in supporting a healthy gastrointestinal microbiota.

5 May 2023

Immune Evasion Mechanism of TNBC Cells Discovered

Freiburg researchers discover a mechanism by which cancer cells escape the immune system.

5 May 2023

Metabolism News and Research

RNA Regulatory Mechanism Involving Stress Granules Directly Regulates Alzheimer’s Development

Antioxidant Enzymes Relocate to the Nucleus in Response to DNA Damage

Study Characterizes the Properties of MAIT Cells in Mouse Lung

New Platform for Production of Synthetic Nitrated Proteins in Bacteria

Identifying Drugs to Put the Brakes On Accelerated Aging From HIV Infection, Treatment

Study Shows How Excess Dietary Sugar Worsens IBD Symptoms

New Insight into the Dynamics of a Ribosomal Protein - RPL3L

Researchers Develop AI Method to Predict Small Molecule Substrates of Enzymes

Researchers Examine the Role of TOR in LR Formation and its Interplay with Auxin Signaling

Untangling the Effects of Admixture on the Genomes of Modern Humans

Targeting Cellular Respiration for the Treatment of Glioblastoma

A High-Throughput Assay for Identifying and Validating ECHS1 Enzyme Genetic Variants

Liver Cells Influence the Body's Internal Circadian Clock, Study Reveals

Researchers Use the Bionanoprobe to Explore Role of Zinc in Follicle Development

Increase in Certain Bacterial Species Indicates Intestinal Candida Fungi Overgrowth

High-Throughput Technique Observes Differences in Hard and Non-Hard Seeds

The Efficiency of AI in Microbial Experiments

Analyzing the Complex Sequence of Events Involved in Beta-Arrestin Interactions

Understanding How Diet may Influence the Gut Microbiota Structure

Immune Evasion Mechanism of TNBC Cells Discovered

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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