Antigen News and Research

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Study uncovers how the immune system generates effective antibodies

An in-depth Garvan study of how the immune system generates effective antibodies provides new insights for vaccine design.

25 Aug 2020

Lasting nature of IBD linked to long-lived immune cell that causes persistent inflammation

Inflammatory bowel disease (IBD) is a group of intestinal disorders affecting an estimated six to eight million people worldwide.

25 Aug 2020

Researchers add a component to make cancer vaccine more effective

Jefferson researchers developing a cancer vaccine to prevent recurrences of gastric, pancreatic, esophageal and colon cancers have added a component that would make the vaccine more effective.

25 Aug 2020

Female reproductive tract capable of mediating post-mating sexual selection

The female reproductive tract has the final say in human mate choice, according to new research from the University of Eastern Finland.

20 Aug 2020

New method targets hidden HIV viral reservoirs during antiretroviral therapy

Scientists at The Wistar Institute may have discovered a new way of identifying and targeting hidden HIV viral reservoirs during treatment with antiretroviral therapy (ART).

10 Aug 2020

How tumor cells evade the immune defense

A new study by the University of Bonn and research institutions in Australia and Switzerland now shows the strategies tumor cells use to evade this attack.

6 Aug 2020

Researchers develop CAR-T cell therapy based on TCR signal transduction

The T cell receptor (TCR) is a key receptor that is responsible for detecting tumor antigens in T cells.

4 Aug 2020

A safer treatment harnesses the body's cancer-fighting T cells to fight multiple myeloma

A treatment for multiple myeloma that harnesses the body's cancer-fighting T cells was safe in humans and showed preliminary signs of effectiveness, according to a clinical trial involving 23 patients with relapsed or treatment-resistant disease.

30 Jul 2020

Clinical trial shows CAR-T cell therapy can be used for treating Hodgkin lymphoma

CAR-T cell therapy, which attacks cancer cells using a person's reprogrammed immune cells, has been used to treat Hodgkin lymphoma with remarkable success for the first time, according to the results of an early phase clinical trial led by researchers at UNC Lineberger Comprehensive Cancer Center and Baylor College of Medicine in Houston.

24 Jul 2020

New approach is more effective in treating certain blood cancers

Some of the most promising advances in cancer treatment have centered on immunotherapies that rev up a patient's immune system to attack cancer.

24 Jul 2020

Study shows neo-self antibody as major cause of recurrent pregnancy loss

A research group centered around Kobe University Graduate School of Medicine's Professor YAMADA Hideto and Associate Professor TANIMURA Kenji (Department of Obstetrics and Gynecology), and Professor ARASE Hisashi et al. of Osaka University's Research Institute for Microbial Diseases have revealed for the first time in the world the high frequency of a novel autoantibody in women suffering from recurrent pregnancy loss.

23 Jul 2020

A novel technique to control and visualize functions of living cells

A research group composed of Professor Takayuki Shibata and his colleagues at Department of Mechanical Engineering, Toyohashi University of Technology has given greater functionalities to atomic force microscopy (AFM).

23 Jul 2020

Study shows how T cells become cancer-killing cells

Within the immune system, the T lymphocytes operate to kill cancer cells or infected cells.

21 Jul 2020

Modified mRNAs improve efficiency of protein synthesis

Since mRNAs play a key role in protein synthesis in vivo, the use of mRNAs as medicines and for in vitro protein synthesis has been desired.

17 Jul 2020

New, promising CAR T cell therapy results in exceptional patient recovery

In a clinical trial evaluating a novel immunotherapy option for cancer treatment, a child with rhabdomyosarcoma, a form of muscle cancer, that had spread to the bone marrow, showed no detectable cancer following treatment with chimeric antigen receptor (CAR) T cells that were engineered to target the HER2 protein on the surface of cancerthe cells.

16 Jul 2020

New radiopharmaceutical offers precise diagnosis and treatment of prostate cancer in preclinical studies

Researchers have developed a new pair of agents that show exceptional effectiveness for precision diagnosis and treatment of prostate cancer in preclinical studies.

14 Jul 2020

Early exposure to vaccine-derived antigens can have dramatic effect on antibody diversity

University of Alabama at Birmingham researchers have added fresh evidence that early exposure to vaccine-, bacterial- or microbiota-derived antigens has a dramatic effect on the diversity of antibodies an adult mammal will have to fight future infections by pathogens.

14 Jul 2020

Antigen News and Research

Study uncovers how the immune system generates effective antibodies

Lasting nature of IBD linked to long-lived immune cell that causes persistent inflammation

Researchers add a component to make cancer vaccine more effective

Female reproductive tract capable of mediating post-mating sexual selection

New method targets hidden HIV viral reservoirs during antiretroviral therapy

How tumor cells evade the immune defense

Researchers develop CAR-T cell therapy based on TCR signal transduction

A safer treatment harnesses the body's cancer-fighting T cells to fight multiple myeloma

Clinical trial shows CAR-T cell therapy can be used for treating Hodgkin lymphoma

New approach is more effective in treating certain blood cancers

Study shows neo-self antibody as major cause of recurrent pregnancy loss

A novel technique to control and visualize functions of living cells

Study shows how T cells become cancer-killing cells

Modified mRNAs improve efficiency of protein synthesis

New, promising CAR T cell therapy results in exceptional patient recovery

New radiopharmaceutical offers precise diagnosis and treatment of prostate cancer in preclinical studies

Early exposure to vaccine-derived antigens can have dramatic effect on antibody diversity

Researchers develop new immunotherapy that prevents reoccurrence of breast cancer

Study confirms the efficacy of PSMA PET/CT in detection and management of recurrent prostate cancer

New technology generates immune response by delivering antigens to APCs in the spleen

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